Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice.
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The role of infections in autoimmune diseaseSevere anaphylactic reactions to glutamic acid decarboxylase (GAD) self peptides in NOD mice that spontaneously develop autoimmune type 1 diabetes mellitusThe Potential for Microalgae as Bioreactors to Produce PharmaceuticalsEnterovirus and type 1 diabetes: What is the matter?Bioluminescence imaging reveals dynamics of beta cell loss in the non-obese diabetic (NOD) mouse modelStructure of a human insulin peptide-HLA-DQ8 complex and susceptibility to type 1 diabetesImogen 38: a novel 38-kD islet mitochondrial autoantigen recognized by T cells from a newly diagnosed type 1 diabetic patientAmino acid residues 24-31 but not palmitoylation of cysteines 30 and 45 are required for membrane anchoring of glutamic acid decarboxylase, GAD65Phosphorylation of serine residues 3, 6, 10, and 13 distinguishes membrane anchored from soluble glutamic acid decarboxylase 65 and is restricted to glutamic acid decarboxylase 65alphaSlc11a1 enhances the autoimmune diabetogenic T-cell response by altering processing and presentation of pancreatic islet antigensOpinion: Satisfaction (not) guaranteed: re-evaluating the use of animal models of type 1 diabetesTRPV1: A Potential Drug Target for Treating Various Diseases.A diabetes-associated T-cell autoantigen maps to a telomeric locus on mouse chromosome 6.Site-directed mutagenesis of K396R of the 65 kDa glutamic acid decarboxylase active site obliterates enzyme activity but not antibody binding.A novel expression platform for the production of diabetes-associated autoantigen human glutamic acid decarboxylase (hGAD65).Glutamic acid decarboxylase-derived epitopes with specific domains expand CD4(+)CD25(+) regulatory T cells.Peptide-based molecular analyses of HLA class II-associated susceptibility to autoimmune diseases.Protection of nonobese diabetic mice from diabetes by intranasal or subcutaneous administration of insulin peptide B-(9-23)Stiff-man syndrome: from the bedside to the bench.Tumor necrosis factor-alpha and the progression of diabetes in non-obese diabetic mice.Transgenes and knockout mutations in animal models of type 1 diabetes and multiple sclerosis.Molecular pathway alterations in CD4 T-cells of nonobese diabetic (NOD) mice in the preinsulitis phase of autoimmune diabetes.Molecular mechanisms of T-cell receptor and costimulatory molecule ligation/blockade in autoimmune disease therapy.Immunotherapy of type 1 diabetes: where are we and where should we be going?Endogenous presentation of self myelin epitopes by CNS-resident APCs in Theiler's virus-infected miceRole of heat shock proteins in protection from and pathogenesis of infectious diseases.Analysis of structure and function relationships of an autoantigenic peptide of insulin bound to H-2K(d) that stimulates CD8 T cells in insulin-dependent diabetes mellitusRestricted islet-cell reactive T cell repertoire of early pancreatic islet infiltrates in NOD mice.The role of TNF-alpha in the pathogenesis of type 1 diabetes in the nonobese diabetic mouse: analysis of dendritic cell maturationCellular immunity to a determinant common to glutamate decarboxylase and coxsackie virus in insulin-dependent diabetesStrategies for preventing type I diabetes mellitusClinical implications of the stress responseSensitization to self (virus) antigen by in situ expression of murine interferon-gamma.Insulin immunization of nonobese diabetic mice induces a protective insulitis characterized by diminished intraislet interferon-gamma transcription.In vivo activity and in vitro specificity of CD4+ Th1 and Th2 cells derived from the spleens of diabetic NOD mice.Epitope spreading: protection from pathogens, but propagation of autoimmunity?Central nervous system destruction mediated by glutamic acid decarboxylase-specific CD4+ T cells.Prevention of type I diabetes transfer by glutamic acid decarboxylase 65 peptide 206-220-specific T cellsA role of Hsp60 in autoimmune diabetes: analysis in a transgenic model.Antigen-based vs. systemic immunomodulation in type 1 diabetes: the pros and cons.
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P2860
Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh-hant
name
Immune response to glutamic ac ...... is in non-obese diabetic mice.
@en
Immune response to glutamic ac ...... is in non-obese diabetic mice.
@nl
type
label
Immune response to glutamic ac ...... is in non-obese diabetic mice.
@en
Immune response to glutamic ac ...... is in non-obese diabetic mice.
@nl
prefLabel
Immune response to glutamic ac ...... is in non-obese diabetic mice.
@en
Immune response to glutamic ac ...... is in non-obese diabetic mice.
@nl
P2093
P356
P1433
P1476
Immune response to glutamic ac ...... is in non-obese diabetic mice.
@en
P2093
P2888
P356
10.1038/366072A0
P407
P577
1993-11-01T00:00:00Z
P6179
1034078560