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Systems biology and biomarkers of early effects for occupational exposure limit settingRevisiting Cohen et al. 2015, Cohen et al. 2014 and Waalkes et al. 2014: a bayesian re-analysis of tumor incidencesThe next generation of risk assessment multiyear study - highlights of findings, applications to risk assessment, and future directionsLoss of Hif-2α Rescues the Hif-1α Deletion Phenotype of Neonatal Respiratory Distress In MiceNon-additive hepatic gene expression elicited by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and 2,2',4,4',5,5'-hexachlorobiphenyl (PCB153) co-treatment in C57BL/6 miceSystematic Omics Analysis Review (SOAR) tool to support risk assessmento,p'-DDT elicits PXR/CAR-, not ER-, mediated responses in the immature ovariectomized rat liverGene expression analysis points to hemostasis in livers of rats cotreated with lipopolysaccharide and ranitidineA Market-Basket Approach to Predict the Acute Aquatic Toxicity of Munitions and Energetic MaterialsBurst and principal components analyses of MEA data for 16 chemicals describe at least three effects classes.What do the data show? Knowledge map development for comprehensive environmental assessment.Can data science inform environmental justice and community risk screening for type 2 diabetes?The need for standards, not guidelines, in biological data reporting and sharing.Using In Vitro High-Throughput Screening Data for Predicting Benzo[k]Fluoranthene Human Health Hazards.Toward a checklist for exchange and interpretation of data from a toxicology study.Automated quantitative dose-response modeling and point of departure determination for large toxicogenomic and high-throughput screening data sets.In vivo-in vitro toxicogenomic comparison of TCDD-elicited gene expression in Hepa1c1c7 mouse hepatoma cells and C57BL/6 hepatic tissueComparative temporal and dose-dependent morphological and transcriptional uterine effects elicited by tamoxifen and ethynylestradiol in immature, ovariectomized mice.Tamoxifen-elicited uterotrophy: cross-species and cross-ligand analysis of the gene expression programEffects of TCDD on the expression of nuclear encoded mitochondrial genesGenome-wide computational analysis of dioxin response element location and distribution in the human, mouse, and rat genomes.Differences in TCDD-elicited gene expression profiles in human HepG2, mouse Hepa1c1c7 and rat H4IIE hepatoma cellsOxidative stress is important in the pathogenesis of liver injury induced by sulindac and lipopolysaccharide cotreatmentA framework for the next generation of risk science.MIPHENO: data normalization for high throughput metabolite analysis.Automated dose-response analysis and comparative toxicogenomic evaluation of the hepatic effects elicited by TCDD, TCDF, and PCB126 in C57BL/6 mice.Hypoxia-inducible factor-1α regulates the expression of genes in hypoxic hepatic stellate cells important for collagen deposition and angiogenesis.Identification and characterization of genes susceptible to transcriptional cross-talk between the hypoxia and dioxin signaling cascadesComparative metabolomic and genomic analyses of TCDD-elicited metabolic disruption in mouse and rat liverClearing the standards landscape: the semantics of terminology and their impact on toxicogenomics.The minimum information required for reporting a molecular interaction experiment (MIMIx).Species-specific regulation of PXR/CAR/ER-target genes in the mouse and rat liver elicited by o, p'-DDTPhenobarbital elicits unique, early changes in the expression of hepatic genes that affect critical pathways in tumor-prone B6C3F1 mice.The constitutive active/androstane receptor facilitates unique phenobarbital-induced expression changes of genes involved in key pathways in precancerous liver and liver tumorsComparative analysis of AhR-mediated TCDD-elicited gene expression in human liver adult stem cells.Estrogen receptor-dependent regulation of CYP2B6 in human breast cancer cells.Comparative analysis of dioxin response elements in human, mouse and rat genomic sequences.PCB153-elicited hepatic responses in the immature, ovariectomized C57BL/6 mice: comparative toxicogenomic effects of dioxin and non-dioxin-like ligands.dbZach toxicogenomic information management system.dbZach: A MIAME-compliant toxicogenomic supportive relational database.
P50
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P50
description
onderzoeker
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researcher
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հետազոտող
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Lyle D. Burgoon
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Lyle D. Burgoon
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Lyle D. Burgoon
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Lyle D. Burgoon
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Lyle D. Burgoon
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Lyle D. Burgoon
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Lyle D. Burgoon
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Lyle D. Burgoon
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Lyle D. Burgoon
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Lyle D. Burgoon
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Lyle D. Burgoon
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Lyle D. Burgoon
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Lyle D. Burgoon
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Lyle D. Burgoon
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P106
P1153
54790504200
P31
P496
0000-0003-4977-5352