about
Activating transcription factor 3 gene expression suggests that tissue stress plays a role in leiomyoma developmentHuman myometrium and leiomyomas express gonadotropin-releasing hormone 2 and gonadotropin-releasing hormone 2 receptorGonadotropin-releasing hormone agonist increases expression of osmotic response genes in leiomyoma cells.Liarozole inhibits transforming growth factor-β3--mediated extracellular matrix formation in human three-dimensional leiomyoma cultures.Alternative therapies in management of leiomyomas.Novel, orally active selective progesterone receptor modulator CP8947 inhibits leiomyoma cell proliferation without adversely affecting endometrium or myometrium.Retinoic acid treatment of human leiomyoma cells transformed the cell phenotype to one strongly resembling myometrial cells.Mechanical homeostasis is altered in uterine leiomyoma.Gonadotropin-releasing hormone analogues inhibit leiomyoma extracellular matrix despite presence of gonadal hormones.Development and validation of a three-dimensional in vitro model for uterine leiomyoma and patient-matched myometrium.Myometrial cells undergo fibrotic transformation under the influence of transforming growth factor beta-3.Why leiomyomas are called fibroids: the central role of extracellular matrix in symptomatic women.Inhibition of colonic aberrant crypt foci by curcumin in rats is affected by age.Effects of commercial anthocyanin-rich extracts on colonic cancer and nontumorigenic colonic cell growth.Curcumin, a nutritional supplement with antineoplastic activity, enhances leiomyoma cell apoptosis and decreases fibronectin expression.Leiomyoma fibrosis inhibited by liarozole, a retinoic acid metabolic blocking agent.Gonadotropin-releasing hormone (GnRH) agonist leuprolide acetate and GnRH antagonist cetrorelix acetate directly inhibit leiomyoma extracellular matrix production.Anthocyanin-rich extracts inhibit multiple biomarkers of colon cancer in rats.Novel method to characterize primary cultures of leiomyoma and myometrium with the use of confirmatory biomarker gene arrays.Rapid method for identification of chemopreventive compounds using multiplex RT-PCR for cyclooxygenase mRNA expression.
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description
hulumtuese
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Minnie Malik
@ast
Minnie Malik
@en
Minnie Malik
@es
Minnie Malik
@nl
Minnie Malik
@sl
type
label
Minnie Malik
@ast
Minnie Malik
@en
Minnie Malik
@es
Minnie Malik
@nl
Minnie Malik
@sl
prefLabel
Minnie Malik
@ast
Minnie Malik
@en
Minnie Malik
@es
Minnie Malik
@nl
Minnie Malik
@sl
P106
P21
P31
P496
0000-0003-1129-6575