about
Radiosynthesis and first preclinical evaluation of the novel norepinephrine transporter pet-ligand [(11)C]ME@HAPTHIDifferential modulation of the default mode network via serotonin-1A receptors[¹⁸F]FE@SNAP-A new PET tracer for the melanin concentrating hormone receptor 1 (MCHR1): microfluidic and vessel-based approaches[(18)F]FE@SNAP-a specific PET tracer for melanin-concentrating hormone receptor 1 imaging?Pilot PET Study to Assess the Functional Interplay Between ABCB1 and ABCG2 at the Human Blood-Brain BarrierPreparation and First Preclinical Evaluation of [(18)F]FE@SNAP: A Potential PET Tracer for the Melanin-Concentrating Hormone Receptor-1 (MCHR1)Effects of Selective Serotonin Reuptake Inhibitors on Interregional Relation of Serotonin Transporter Availability in Major Depression.The influence of the rs6295 gene polymorphism on serotonin-1A receptor distribution investigated with PET in patients with major depression applying machine learning.Effect of P-glycoprotein inhibition at the blood-brain barrier on brain distribution of (R)-[11 C]verapamil in elderly vs. young subjects.Simple and rapid quantification of serotonin transporter binding using [11C]DASB bolus plus constant infusion.Association of Protein Distribution and Gene Expression Revealed by PET and Post-Mortem Quantification in the Serotonergic System of the Human Brain.Whole-Body Distribution and Radiation Dosimetry of 11C-Elacridar and 11C-Tariquidar in Humans.Approaching complete inhibition of P-glycoprotein at the human blood-brain barrier: an (R)-[11C]verapamil PET study.In vivo evaluation of radiotracers targeting the melanin-concentrating hormone receptor 1: [11C]SNAP-7941 and [18F]FE@SNAP reveal specific uptake in the ventricular system.Interaction of 11C-tariquidar and 11C-elacridar with P-glycoprotein and breast cancer resistance protein at the human blood-brain barrier.Reliable set-up for in-loop ¹¹C-carboxylations using Grignard reactions for the preparation of [carbonyl-¹¹C]WAY-100635 and [¹¹C]-(+)-PHNO.Radiosynthesis of [11C]SNAP-7941--the first PET-tracer for the melanin concentrating hormone receptor 1 (MCHR1).Parameter evaluation and fully-automated radiosynthesis of [(11)C]harmine for imaging of MAO-A for clinical trials.Cerebral serotonin transporter asymmetry in females, males and male-to-female transsexuals measured by PET in vivo.Syntheses of precursors and reference compounds of the melanin-concentrating hormone receptor 1 (MCHR1) tracers [¹¹C]SNAP-7941 and [¹⁸F]FE@SNAP for positron emission tomography.Regional differences in SERT occupancy after acute and prolonged SSRI intake investigated by brain PET.Simple and rapid preparation of [11C]DASB with high quality and reliability for routine applications.Prediction of SSRI treatment response in major depression based on serotonin transporter interplay between median raphe nucleus and projection areas.Influence of OATPs on Hepatic Disposition of Erlotinib Measured With Positron Emission Tomography.Preclinical in vitro &in vivo evaluation of [(11)C]SNAP-7941 - the first PET tracer for the melanin concentrating hormone receptor 1.Speed matters to raise molar radioactivity: Fast HPLC shortens the quality control of C-11 PET-tracers.Altered interregional molecular associations of the serotonin transporter in attention deficit/hyperactivity disorder assessed with PET.Microfluidic 68Ga-labeling: a proof of principle study.A new method measuring the interaction of radiotracers with the human P-glycoprotein (P-gp) transporter.Optimization of the radiosynthesis of the Alzheimer tracer 2-(4-N-[11C]methylaminophenyl)-6-hydroxybenzothiazole ([11C]PIB).Parcellation of the Human Cerebral Cortex Based on Molecular Targets in the Serotonin System Quantified by Positron Emission Tomography In vivoMolar activity - The keystone in C-radiochemistry: An explorative study using the gas phase methodBrain monoamine oxidase A in seasonal affective disorder and treatment with bright light therapyOptimization of the Automated Synthesis of [11C]mHED—Administered and Apparent Molar ActivitiesSNAPshots of the MCHR1: a Comparison Between the PET-Tracers [18F]FE@SNAP and [11C]SNAP-7941Comparative autoradiographic in vitro investigation of melanin concentrating hormone receptor 1 ligands in the central nervous systemOptimization of [11C]DASB-synthesis: Vessel-based and flow-through microreactor methodsMicrofluidic preparation of [18F]FE@SUPPY and [18F]FE@SUPPY:2 — comparison with conventional radiosynthesesAn Overview of PET Radiochemistry, Part 1: The Covalent Labels 18F, 11C, and 13NToward the Optimization of (+)-[11C]PHNO Synthesis: Time Reduction and Process Validation
P50
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P50
description
physician
@en
wetenschapper
@nl
name
Cecile Philippe
@ast
Cecile Philippe
@en
Cecile Philippe
@es
Cecile Philippe
@nl
Cecile Philippe
@sl
type
label
Cecile Philippe
@ast
Cecile Philippe
@en
Cecile Philippe
@es
Cecile Philippe
@nl
Cecile Philippe
@sl
prefLabel
Cecile Philippe
@ast
Cecile Philippe
@en
Cecile Philippe
@es
Cecile Philippe
@nl
Cecile Philippe
@sl
P106
P1153
34768928200
P31
P496
0000-0002-7203-7174