Identification of a peptide inhibitor for the histone methyltransferase WHSC1.

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High-throughput screening with nucleosome substrate identifies small-molecule inhibitors of the human histone lysine methyltransferase NSD2

P2860

Q58977715-5B39A0AD-7463-4401-B26B-E51B30DAA678

P2860

Identification of a peptide inhibitor for the histone methyltransferase WHSC1.

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2018 nî lūn-bûn

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2018年の論文

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name

Identification of a peptide inhibitor for the histone methyltransferase WHSC1.

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Identification of a peptide inhibitor for the histone methyltransferase WHSC1.

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Item

label

Identification of a peptide inhibitor for the histone methyltransferase WHSC1.

@en

Identification of a peptide inhibitor for the histone methyltransferase WHSC1.

@nl

prefLabel

Identification of a peptide inhibitor for the histone methyltransferase WHSC1.

@en

Identification of a peptide inhibitor for the histone methyltransferase WHSC1.

@nl

P1476

Identification of a peptide inhibitor for the histone methyltransferase WHSC1.

@en

P2093

Darren M Harvey

http://www.w3.org/2001/XMLSchema#string

Dipti Sadalge

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John W Lampe

http://www.w3.org/2001/XMLSchema#string

Kenneth W Duncan

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Kerren K Swinger

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Kevin W Kuntz

http://www.w3.org/2001/XMLSchema#string

Lorna H Mitchell

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Margaret Porter Scott

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P Ann Boriack-Sjodin

http://www.w3.org/2001/XMLSchema#string

Richard Chesworth

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P2860

WHSC1, a 90 kb SET domain-containing gene, expressed in early development and homologous to a Drosophila dysmorphy gene maps in the Wolf-Hirschhorn syndrome critical region and is fused to IgH in t(4;14) multiple myeloma

The structure of NSD1 reveals an autoregulatory mechanism underlying histone H3K36 methylation

Crystal structure of the human histone methyltransferase ASH1L catalytic domain and its implications for the regulatory mechanism

A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells

Structural basis for G9a-like protein lysine methyltransferase inhibition by BIX-01294

Discovery of a 2,4-Diamino-7-aminoalkoxyquinazoline as a Potent and Selective Inhibitor of Histone Lysine Methyltransferase G9a

Chemogenetic analysis of human protein methyltransferases

Structural basis of substrate methylation and inhibition of SMYD2

Selective Inhibitors of Histone Methyltransferase DOT1L: Design, Synthesis, and Crystallographic Studies

Potent inhibition of DOT1L as treatment of MLL-fusion leukemia

P304

e0197082

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scholarly article

P356

10.1371/JOURNAL.PONE.0197082

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P407

English

P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Michael J Morrison

P577

2018-05-09T00:00:00Z

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P698

29742153

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P932

5942779

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Identification of a peptide inhibitor for the histone methyltransferase WHSC1.

about

P2860

P2860

Identification of a peptide inhibitor for the histone methyltransferase WHSC1.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P932