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The PGD2 pathway, independently of FGF9, amplifies SOX9 activity in Sertoli cells during male sexual differentiationTestis cord differentiation after the sex determination stage is independent of Sox9 but fails in the combined absence of Sox9 and Sox8The SLE variant Ala71Thr of BLK severely decreases protein abundance and binding to BANK1 through impairment of the SH3 domain function.Concordance of increased B1 cell subset and lupus phenotypes in mice and humans is dependent on BLK expression levels.The mercaptopyruvate sulfurtransferase of Trichomonas vaginalis links cysteine catabolism to the production of thioredoxin persulfide.Copy number variation of two separate regulatory regions upstream of SOX9 causes isolated 46,XY or 46,XX disorder of sex development.Sox9 and Sox8 are required for basal lamina integrity of testis cords and for suppression of FOXL2 during embryonic testis development in mice.Dicer is required for Sertoli cell function and survival.Mutations of the SRY-responsive enhancer of SOX9 are uncommon in XY gonadal dysgenesisBANK1 interacts with TRAF6 and MyD88 in innate immune signaling in B cells
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P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
I Georg
@ast
I Georg
@en
I Georg
@es
I Georg
@nl
I Georg
@sl
type
label
I Georg
@ast
I Georg
@en
I Georg
@es
I Georg
@nl
I Georg
@sl
prefLabel
I Georg
@ast
I Georg
@en
I Georg
@es
I Georg
@nl
I Georg
@sl
P106
P21
P31
P496
0000-0002-1256-5805