about
The lectin domains of polypeptide GalNAc-transferases exhibit carbohydrate-binding specificity for GalNAc: lectin binding to GalNAc-glycopeptide substrates is required for high density GalNAc-O-glycosylation.O-linked glycosylation of the mucin domain of the herpes simplex virus type 1-specific glycoprotein gC-1 is temporally regulated in a seed-and-spread mannerA glycogene mutation map for discovery of diseases of glycosylation.Involvement of O-glycosylation defining oncofetal fibronectin in epithelial-mesenchymal transition processThe Breast Cancer-Associated Glycoforms of MUC1, MUC1-Tn and sialyl-Tn, Are Expressed in COSMC Wild-Type Cells and Bind the C-Type Lectin MGL.Probing the O-glycoproteome of gastric cancer cell lines for biomarker discovery.Probing isoform-specific functions of polypeptide GalNAc-transferases using zinc finger nuclease glycoengineered SimpleCellsPrecision mapping of the human O-GalNAc glycoproteome through SimpleCell technology.Site-specific O-glycosylation on the MUC2 mucin protein inhibits cleavage by the Porphyromonas gingivalis secreted cysteine protease (RgpB).Autoantibodies to MUC1 glycopeptides cannot be used as a screening assay for early detection of breast, ovarian, lung or pancreatic cancerMucins and associated glycan signatures in colon adenoma-carcinoma sequence: Prospective pathological implication(s) for early diagnosis of colon cancer.Identification of new cancer biomarkers based on aberrant mucin glycoforms by in situ proximity ligation.Engineered CAR T Cells Targeting the Cancer-Associated Tn-Glycoform of the Membrane Mucin MUC1 Control AdenocarcinomaGeneration and characterization of a monoclonal antibody to the cytoplasmic tail of MUC16.Microarray Glycoprofiling of CA125 improves differential diagnosis of ovarian cancer.Mining the O-glycoproteome using zinc-finger nuclease-glycoengineered SimpleCell lines.Engineering mammalian mucin-type O-glycosylation in plants.Loss of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3 and reduced O-glycosylation in colon carcinoma cells selected for hepatic metastasis.Chemoenzymatically synthesized multimeric Tn/STn MUC1 glycopeptides elicit cancer-specific anti-MUC1 antibody responses and override tolerance.A novel monoclonal antibody to a defined peptide epitope in MUC16.Detection of glyco-mucin profiles improves specificity of MUC16 and MUC1 biomarkers in ovarian serous tumours.Simple mucin-type carbohydrate antigens in pleomorphic adenomas.Reduced sulfation of muc5b is linked to xerostomia in patients with Sjögren syndrome.De novo expression of human polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6) in colon adenocarcinoma inhibits the differentiation of colonic epithelium.GLYCAN-DIRECTED CAR-T CELLS.Characterization of binding epitopes of CA125 monoclonal antibodies.ST6GalNAc-I controls expression of sialyl-Tn antigen in gastrointestinal tissues.Egghead and brainiac are essential for glycosphingolipid biosynthesis in vivo.Rescue of Drosophila Melanogaster l(2)35Aa lethality is only mediated by polypeptide GalNAc-transferase pgant35A, but not by the evolutionary conserved human ortholog GalNAc-transferase-T11.Decreased salivary sulphotransferase activity correlated with inflammation and autoimmunity parameters in Sjogren's syndrome patients.Asthma induction in mice leads to appearance of alpha2-3- and alpha2-6-linked sialic acid residues in respiratory goblet-like cells.Aberrantly glycosylated MUC1 is expressed on the surface of breast cancer cells and a target for antibody-dependent cell-mediated cytotoxicitySeromic profiling of colorectal cancer patients with novel glycopeptide microarrayLoss of a novel mucin-like epithelial glycoprotein in oral and cervical squamous cell carcinomasToward stable genetic engineering of human O-glycosylation in plantsTumor-Associated Tn-MUC1 Glycoform Is Internalized through the Macrophage Galactose-Type C-Type Lectin and Delivered to the HLA Class I and II Compartments in Dendritic CellsMucins and Truncated -Glycans Unveil Phenotypic Discrepancies between Serous Ovarian Cancer Cell Lines and Primary TumoursExpression of Mucin-1 in multiple myeloma and its precursors: correlation with glycosylation and subcellular localizationAltered Expression of Epithelial Cell Surface Glycoconjugates and Intermediate Filaments at the Margins of Mucosal WoundsThe Thomsen-Friedenreich (T) simple mucin-type carbohydrate antigen in salivary gland carcinomas
P50
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P50
description
hulumtuese
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Ulla Mandel
@ast
Ulla Mandel
@en
Ulla Mandel
@es
Ulla Mandel
@nl
Ulla Mandel
@sl
type
label
Ulla Mandel
@ast
Ulla Mandel
@en
Ulla Mandel
@es
Ulla Mandel
@nl
Ulla Mandel
@sl
prefLabel
Ulla Mandel
@ast
Ulla Mandel
@en
Ulla Mandel
@es
Ulla Mandel
@nl
Ulla Mandel
@sl
P106
P21
P31
P496
0000-0001-7012-9836