about
CHEK2 mutations affecting kinase activity together with mutations in TP53 indicate a functional pathway associated with resistance to epirubicin in primary breast cancerSignatures of mutational processes in human cancerInverse regulation of EGFR/HER1 and HER2-4 in normal and malignant human breast tissue.Chemosensitivity and p53; new tricks by an old dogRecent data on intratumor estrogens in breast cancer.Predictive and prognostic impact of TP53 mutations and MDM2 promoter genotype in primary breast cancer patients treated with epirubicin or paclitaxel.Identification and characterization of retinoblastoma gene mutations disturbing apoptosis in human breast cancersLandscape of somatic mutations in 560 breast cancer whole-genome sequences.Association of a germline copy number polymorphism of APOBEC3A and APOBEC3B with burden of putative APOBEC-dependent mutations in breast cancerMDM2 promoter SNP344T>A (rs1196333) status does not affect cancer risk.Effect of the MDM2 promoter polymorphisms SNP309T>G and SNP285G>C on the risk of ovarian cancer in BRCA1 mutation carriers.Population distribution and ancestry of the cancer protective MDM2 SNP285 (rs117039649).TP53 status predicts long-term survival in locally advanced breast cancer after primary chemotherapy.Alterations of the retinoblastoma gene in metastatic breast cancerPerformance comparison of three BRAF V600E detection methods in malignant melanoma and colorectal cancer specimens.Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes.Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells.MDM2 promoter SNP285 and SNP309; phylogeny and impact on cancer riskEffects of the MDM2 promoter SNP285 and SNP309 on Sp1 transcription factor binding and cancer risk.Estrogens Correlate with PELP1 Expression in ER Positive Breast CancerSubclonal diversification of primary breast cancer revealed by multiregion sequencing.Intra-patient Inter-metastatic Genetic Heterogeneity in Colorectal Cancer as a Key Determinant of Survival after Curative Liver Resection.Low expression levels of ATM may substitute for CHEK2 /TP53 mutations predicting resistance towards anthracycline and mitomycin chemotherapy in breast cancer.MDM2 promoter polymorphism del1518 (rs3730485) and its impact on endometrial and ovarian cancer riskImpact of the MDM2 splice-variants MDM2-A, MDM2-B and MDM2-C on cytotoxic stress response in breast cancer cellsBreast cancer prognostication and prediction in the postgenomic era.The MDM4 SNP34091 (rs4245739) C-allele is associated with increased risk of ovarian-but not endometrial cancerMDM2 promoter SNP55 (rs2870820) affects risk of colon cancer but not breast-, lung-, or prostate cancer.Prevalence of the CHEK2 R95* germline mutationCXXC5 (retinoid-inducible nuclear factor, RINF) is a potential therapeutic target in high-risk human acute myeloid leukemiaBreast cancer genome and transcriptome integration implicates specific mutational signatures with immune cell infiltration.Associations between the MDM2 promoter P1 polymorphism del1518 (rs3730485) and incidence of cancer of the breast, lung, colon and prostate.Low BRAF and NRAS expression levels are associated with clinical benefit from DTIC therapy and prognosis in metastatic melanomaImpact of KRAS, BRAF, PIK3CA, TP53 status and intraindividual mutation heterogeneity on outcome after liver resection for colorectal cancer metastasesMDM4 SNP34091 (rs4245739) and its effect on breast-, colon-, lung-, and prostate cancer risk.Exploring breast cancer estrogen disposition: the basis for endocrine manipulation.P53 and its molecular basis to chemoresistance in breast cancer.Mapping genetic alterations causing chemoresistance in cancer: identifying the roads by tracking the drivers.The Functional Roles of the MDM2 Splice Variants P2-MDM2-10 and MDM2-∆5 in Breast Cancer CellsGenomic Evolution of Breast Cancer Metastasis and Relapse.
P50
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Noors onderzoeker
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հետազոտող
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Stian Knappskog
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Stian Knappskog
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Stian Knappskog
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Stian Knappskog
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Stian Knappskog
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Stian Knappskog
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Stian Knappskog
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Stian Knappskog
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Stian Knappskog
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Stian Knappskog
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Stian Knappskog
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Stian Knappskog
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Stian Knappskog
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Stian Knappskog
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Stian Knappskog
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Stian Knappskog
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Stian Knappskog
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Stian Knappskog
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Stian Knappskog
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Stian Knappskog
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Stian Knappskog
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Stian Knappskog
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Stian Knappskog
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Stian Knappskog
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Stian Knappskog
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0000-0002-4153-1655