Improved skeletal muscle oxidative enzyme activity and restoration of PGC-1α and PPARβ/δ gene expression upon rosiglitazone treatment in obese patients with type 2 diabetes mellitus
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Oxidative stress in the pathogenesis of atherothrombosis associated with anti-phospholipid syndrome and systemic lupus erythematosus: new therapeutic approachesA combination of nutriments improves mitochondrial biogenesis and function in skeletal muscle of type 2 diabetic Goto-Kakizaki ratsUCP4 overexpression improves fatty acid oxidation and insulin sensitivity in L6 myocytesRestoration of muscle mitochondrial function and metabolic flexibility in type 2 diabetes by exercise training is paralleled by increased myocellular fat storage and improved insulin sensitivityPioglitazone treatment restores in vivo muscle oxidative capacity in a rat model of diabetes.Pioglitazone enhances mitochondrial biogenesis and ribosomal protein biosynthesis in skeletal muscle in polycystic ovary syndrome.Anti-inflammatory effect of rosiglitazone is not reflected in expression of NFkappaB-related genes in peripheral blood mononuclear cells of patients with type 2 diabetes mellitus.Deficiency of electron transport chain in human skeletal muscle mitochondria in type 2 diabetes mellitus and obesity.Mitochondrial dysfunction in diabetes: from molecular mechanisms to functional significance and therapeutic opportunities.Alterations in skeletal muscle indicators of mitochondrial structure and biogenesis in patients with type 2 diabetes and heart failure: effects of epicatechin rich cocoa.The role of mitochondria in the pathophysiology of skeletal muscle insulin resistance.Insulin Treatment Attenuates Decline of Muscle Mass in Japanese Patients with Type 2 Diabetes.Skeletal muscle mitochondrial and metabolic responses to a high-fat diet in female rats bred for high and low aerobic capacity.Regulation of mitochondrial biogenesisDevelopment of Therapeutics That Induce Mitochondrial Biogenesis for the Treatment of Acute and Chronic Degenerative Diseases.Hyperglycemia predicts persistently lower muscle strength with aging.Pioglitazone leads to an inactivation and disassembly of complex I of the mitochondrial respiratory chainMicroarray analysis suggests that burn injury results in mitochondrial dysfunction in human skeletal muscle.Adipocyte mitochondrial genes and the forkhead factor FOXC2 are decreased in type 2 diabetes patients and normalized in response to rosiglitazoneMitochondrial dysregulation in the pathogenesis of diabetes: potential for mitochondrial biogenesis-mediated interventions.Rosiglitazone Restores Endothelial Dysfunction in a Rat Model of Metabolic Syndrome through PPARγ- and PPARδ-Dependent Phosphorylation of Akt and eNOS.Differential healing after sirolimus, paclitaxel, and bare metal stent placement in combination with peroxisome proliferator-activator receptor gamma agonists: requirement for mTOR/Akt2 in PPARgamma activationEarly Life Stress Induced by Limited Nesting Material Produces Metabolic Resilience in Response to a High-Fat and High-Sugar Diet in Male Rats.E2F transcription factor-1 deficiency reduces pathophysiology in the mouse model of Duchenne muscular dystrophy through increased muscle oxidative metabolism.Role of TRIB3 in regulation of insulin sensitivity and nutrient metabolism during short-term fasting and nutrient excessMitochondrial biogenesis in epithelial cancer cells promotes breast cancer tumor growth and confers autophagy resistance.PGC-1alpha integrates insulin signaling, mitochondrial regulation, and bioenergetic function in skeletal muscleThe role of muscle insulin resistance in the pathogenesis of atherogenic dyslipidemia and nonalcoholic fatty liver disease associated with the metabolic syndrome.Rat Urinary Bladder Carcinogenesis by Dual-Acting PPARalpha + gamma AgonistsMuscle development and obesity: Is there a relationship?The effect of exercise training combined with PPARγ agonist on skeletal muscle glucose uptake and insulin sensitivity in induced diabetic obese Zucker rats.Inactivation of GSK-3beta by metallothionein prevents diabetes-related changes in cardiac energy metabolism, inflammation, nitrosative damage, and remodelingPGC-1alpha in aging and anti-aging interventions.E2F transcription factor-1 regulates oxidative metabolism.PGC-1alpha, SIRT1 and AMPK, an energy sensing network that controls energy expenditure.The transcriptional coactivator PGC-1alpha mediates exercise-induced angiogenesis in skeletal muscle.Metabolomic and Lipidomic Analysis of the Heart of Peroxisome Proliferator-Activated Receptor-γ Coactivator 1-β Knock Out Mice on a High Fat Diet.Genetic models of PGC-1 and glucose metabolism and homeostasisPerspectives and potential applications of mitochondria-targeted antioxidants in cardiometabolic diseases and type 2 diabetes.Sarcopenia and frailty in older patients with diabetes mellitus.
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Improved skeletal muscle oxidative enzyme activity and restoration of PGC-1α and PPARβ/δ gene expression upon rosiglitazone treatment in obese patients with type 2 diabetes mellitus
description
article
@en
im Februar 2007 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована в лютому 2007
@uk
ലേഖനം
@ml
name
Improved skeletal muscle oxida ...... with type 2 diabetes mellitus
@en
Improved skeletal muscle oxida ...... with type 2 diabetes mellitus
@nl
type
label
Improved skeletal muscle oxida ...... with type 2 diabetes mellitus
@en
Improved skeletal muscle oxida ...... with type 2 diabetes mellitus
@nl
prefLabel
Improved skeletal muscle oxida ...... with type 2 diabetes mellitus
@en
Improved skeletal muscle oxida ...... with type 2 diabetes mellitus
@nl
P2093
P921
P356
P1476
Improved skeletal muscle oxida ...... with type 2 diabetes mellitus
@en
P2093
M K C Hesselink
P2888
P304
P356
10.1038/SJ.IJO.0803567
P407
P577
2007-02-20T00:00:00Z
P5875
P6179
1008167071