about
Respiratory syncytial virus infects and abortively replicates in the lungs in spite of preexisting immunityThe cotton rat provides a useful small-animal model for the study of influenza virus pathogenesis.Evaluation of the potential effects of AS03-adjuvanted A(H1N1)pdm09 vaccine administration on the central nervous system of non-primed and A(H1N1)pdm09-primed cotton ratsThe anti-tumor agent, 5,6-dimethylxanthenone-4-acetic acid (DMXAA), induces IFN-beta-mediated antiviral activity in vitro and in vivo.Receptor characterization and susceptibility of cotton rats to avian and 2009 pandemic influenza virus strainsInactivation of respiratory syncytial virus by zinc finger reactive compounds.New insights for development of a safe and protective RSV vaccinePROPHYLACTIC ANTIBODY TREATMENT AND INTRAMUSCULAR IMMUNIZATION REDUCE INFECTIOUS HUMAN RHINOVIRUS 16 LOAD IN THE LOWER RESPIRATORY TRACT OF CHALLENGED COTTON RATS.Agents that increase AAM differentiation blunt RSV-mediated lung pathology.A live RSV vaccine with engineered thermostability is immunogenic in cotton rats despite high attenuationTranscription factor TFIIB and the vitamin D receptor cooperatively activate ligand-dependent transcription.Novel drugs targeting Toll-like receptors for antiviral therapy.Modeling Human Respiratory Viral Infections in the Cotton Rat (Sigmodon hispidus).The histone acetylase PCAF is a nuclear receptor coactivator.Efficacy of the Herpes Simplex Virus 2 (HSV-2) Glycoprotein D/AS04 Vaccine against Genital HSV-2 and HSV-1 Infection and Disease in the Cotton Rat Sigmodon hispidus Model.Cotton rat immune responses to virus-like particles containing the pre-fusion form of respiratory syncytial virus fusion protein.A Recombinant Respiratory Syncytial Virus Vaccine Candidate Attenuated by a Low-Fusion F Protein Is Immunogenic and Protective against Challenge in Cotton RatsExpression of Human CD4 and chemokine receptors in cotton rat cells confers permissiveness for productive HIV infection.Early diagnosis of toxoplasmic encephalitis in AIDS patients by dot blot hybridization analysis.Enterovirus D-68 Infection, Prophylaxis, and Vaccination in a Novel Permissive Animal Model, the Cotton Rat (Sigmodon hispidus).Novel strategies for targeting innate immune responses to influenza.Maternal transfer of RSV immunity in cotton rats vaccinated during pregnancy.TLR4 antagonist FP7 inhibits LPS-induced cytokine production and glycolytic reprogramming in dendritic cells, and protects mice from lethal influenza infection.A recombinant anchorless respiratory syncytial virus (RSV) fusion (F) protein/monophosphoryl lipid A (MPL) vaccine protects against RSV-induced replication and lung pathology.Role of the lipoxygenase pathway in RSV-induced alternatively activated macrophages leading to resolution of lung pathology.Preclinical assessment of safety of maternal vaccination against respiratory syncytial virus (RSV) in cotton rats.Epigenetic Mechanisms Governing Innate Inflammatory Responses.Methods for monitoring dynamics of pulmonary RSV replication by viral culture and by real-time reverse transcription-PCR in vivo: Detection of abortive viral replication.The antiviral potential of interferon-induced cotton rat Mx proteins against orthomyxovirus (influenza), rhabdovirus, and bunyavirus.Pathogenesis of human metapneumovirus lung infection in BALB/c mice and cotton ratsThe cotton rat model of respiratory viral infectionsTreatment with novel RSV Ig RI-002 controls viral replication and reduces pulmonary damage in immunocompromised Sigmodon hispidus.The cotton rat Sigmodon hispidus model of respiratory syncytial virus infection.Human metapneumovirus: enhanced pulmonary disease in cotton rats immunized with formalin-inactivated virus vaccine and challenged.Mutations in the 1,25-dihydroxyvitamin D3 receptor identifying C-terminal amino acids required for transcriptional activation that are functionally dissociated from hormone binding, heterodimeric DNA binding, and interaction with basal transcriptionInduction of type I interferons and interferon-inducible Mx genes during respiratory syncytial virus infection and reinfection in cotton rats.A cotton rat model of human parainfluenza 3 laryngotracheitis: virus growth, pathology, and therapy.Characterization of late tuberculosis infection in Sigmodon hispidus.Co-infection of the cotton rat (Sigmodon hispidus) with Staphylococcus aureus and influenza A virus results in synergistic disease.The TLR4 agonist, monophosphoryl lipid A, attenuates the cytokine storm associated with respiratory syncytial virus vaccine-enhanced disease.
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description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Jorge C Blanco
@ast
Jorge C Blanco
@en
Jorge C Blanco
@es
Jorge C Blanco
@nl
Jorge C Blanco
@sl
type
label
Jorge C Blanco
@ast
Jorge C Blanco
@en
Jorge C Blanco
@es
Jorge C Blanco
@nl
Jorge C Blanco
@sl
prefLabel
Jorge C Blanco
@ast
Jorge C Blanco
@en
Jorge C Blanco
@es
Jorge C Blanco
@nl
Jorge C Blanco
@sl
P106
P21
P31
P496
0000-0002-6173-0213