KRAS mutant allele-specific expression knockdown in pancreatic cancer model with systemically delivered bi-shRNA KRAS lipoplex.

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KRAS mutant allele-specific expression knockdown in pancreatic cancer model with systemically delivered bi-shRNA KRAS lipoplex.

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2018 nî lūn-bûn

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2018年の論文

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年學術文章

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KRAS mutant allele-specific ex ...... ivered bi-shRNA KRAS lipoplex.

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KRAS mutant allele-specific ex ...... ivered bi-shRNA KRAS lipoplex.

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KRAS mutant allele-specific ex ...... ivered bi-shRNA KRAS lipoplex.

@en

KRAS mutant allele-specific ex ...... ivered bi-shRNA KRAS lipoplex.

@nl

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KRAS mutant allele-specific ex ...... ivered bi-shRNA KRAS lipoplex.

@en

KRAS mutant allele-specific ex ...... ivered bi-shRNA KRAS lipoplex.

@nl

P1476

KRAS mutant allele-specific ex ...... ivered bi-shRNA KRAS lipoplex.

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P2093

Christopher M Jay

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Donald D Rao

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Francis C Brunicardi

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Luisa Manning

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Neil Senzer

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Xiuquan Luo

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Zhaohui Wang

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P2860

Hallmarks of Cancer: The Next Generation

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

K-Ras protein as a drug target

A MAPK-Driven Feedback Loop Suppresses Rac Activity to Promote RhoA-Driven Cancer Cell Invasion

Negative feedback regulation of the ERK1/2 MAPK pathway

Systematic quantification of negative feedback mechanisms in the extracellular signal-regulated kinase (ERK) signaling network.

Designing siRNA that distinguish between genes that differ by a single nucleotide

Analysis of siRNA specificity on targets with double-nucleotide mismatches

Enhancement of allele discrimination by introduction of nucleotide mismatches into siRNA in allele-specific gene silencing by RNAi.

A gene expression signature of RAS pathway dependence predicts response to PI3K and RAS pathway inhibitors and expands the population of RAS pathway activated tumors.

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e0193644

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scholarly article

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10.1371/JOURNAL.PONE.0193644

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English

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P478

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P50

William A Maltese

John Nemunaitis

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2018-05-31T00:00:00Z

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29851957

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P932

5979018

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