about
The centriolar satellite protein Cep131 is important for genome stabilityCcdc13 is a novel human centriolar satellite protein required for ciliogenesis and genome stabilityCK2 phospho-dependent binding of R2TP complex to TEL2 is essential for mTOR and SMG1 stabilityRTEL1 maintains genomic stability by suppressing homologous recombinationCiliogenesis and the DNA damage response: a stressful relationshipMRNIP/C5orf45 Interacts with the MRN Complex and Contributes to the DNA Damage ResponseDownregulation of homologous recombination DNA repair genes by HDAC inhibition in prostate cancer is mediated through the E2F1 transcription factorNovel therapeutic strategies in prostate cancer management using gene therapy in combination with radiation therapy.The leukemia-associated Rho guanine nucleotide exchange factor LARG is required for efficient replication stress signaling.Low-dose hyper-radiosensitivity: a consequence of ineffective cell cycle arrest of radiation-damaged G2-phase cells.Enhanced radiation response through directed molecular targeting approaches.The life and death of DNA-PK.DOG-1 is the Caenorhabditis elegans BRIP1/FANCJ homologue and functions in interstrand cross-link repairLow-dose hyper-radiosensitivity: past, present, and future.FANCD2 re-expression is associated with glioma grade and chemical inhibition of the Fanconi Anaemia pathway sensitises gliomas to chemotherapeutic agents.FANCM: fork pause, rewind and play.FANCM and FAAP24 function in ATR-mediated checkpoint signaling independently of the Fanconi anemia core complex.Transition in survival from low-dose hyper-radiosensitivity to increased radioresistance is independent of activation of ATM Ser1981 activity.Evasion of early cellular response mechanisms following low level radiation-induced DNA damage.Expression of the DNA-PK binding protein E4-34K fails to confer radiation sensitivity to mammalian cells.Preventing nonhomologous end joining suppresses DNA repair defects of Fanconi anemia.The 'Ins and Outs' of Early Preclinical Models for Brain Tumor Research: Are They Valuable and Have We Been Doing It Wrong?C. elegans FANCD2 responds to replication stress and functions in interstrand cross-link repairEML4-ALK V3 oncogenic fusion proteins promote microtubule stabilization and accelerated migration through NEK9 and NEK7
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description
onderzoeker
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researcher
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հետազոտող
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Spencer J. Collis
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Spencer J. Collis
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Spencer J. Collis
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Spencer J. Collis
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Spencer J. Collis
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Spencer J. Collis
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Spencer J. Collis
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Spencer J. Collis
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Spencer J. Collis
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Spencer J. Collis
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Spencer J. Collis
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Spencer J. Collis
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Spencer J. Collis
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Spencer J. Collis
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Spencer J. Collis
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P106
P1153
7003553594
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P496
0000-0002-7874-1891