Live-cell single-molecule dynamics of PcG proteins imposed by the DIPG H3.3K27M mutation.

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H3.3K27M mutant proteins reprogram epigenome by sequestering the PRC2 complex to poised enhancers.Multiple modes of PRC2 inhibition elicit global chromatin alterations in H3K27M pediatric glioma

P2860

Q55447974-D5495EC2-2BD8-466B-9611-1549193231C6 Q58587915-D60C91C4-D792-439D-A0DE-E878B5E0F06A

P2860

Live-cell single-molecule dynamics of PcG proteins imposed by the DIPG H3.3K27M mutation.

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http://www.wikidata.org/entity/Q55317685

description

2018 nî lūn-bûn

@nan

2018年の論文

@ja

2018年学术文章

@wuu

2018年学术文章

@zh-cn

2018年学术文章

@zh-hans

2018年学术文章

@zh-my

2018年学术文章

@zh-sg

2018年學術文章

@yue

2018年學術文章

@zh

2018年學術文章

@zh-hant

name

Live-cell single-molecule dynamics of PcG proteins imposed by the DIPG H3.3K27M mutation.

@en

Live-cell single-molecule dynamics of PcG proteins imposed by the DIPG H3.3K27M mutation.

@nl

type

Item

label

Live-cell single-molecule dynamics of PcG proteins imposed by the DIPG H3.3K27M mutation.

@en

Live-cell single-molecule dynamics of PcG proteins imposed by the DIPG H3.3K27M mutation.

@nl

prefLabel

Live-cell single-molecule dynamics of PcG proteins imposed by the DIPG H3.3K27M mutation.

@en

Live-cell single-molecule dynamics of PcG proteins imposed by the DIPG H3.3K27M mutation.

@nl

P1476

Live-cell single-molecule dynamics of PcG proteins imposed by the DIPG H3.3K27M mutation.

@en

P2093

Benjamin Schmitt

http://www.w3.org/2001/XMLSchema#string

Christopher Phiel

http://www.w3.org/2001/XMLSchema#string

Dong Fang

http://www.w3.org/2001/XMLSchema#string

Haobin Wang

http://www.w3.org/2001/XMLSchema#string

Huy Nguyen Duc

http://www.w3.org/2001/XMLSchema#string

Roubina Tatavosian

http://www.w3.org/2001/XMLSchema#string

Thao Ngoc Huynh

http://www.w3.org/2001/XMLSchema#string

Tingting Yao

http://www.w3.org/2001/XMLSchema#string

Xiaodong Shi

http://www.w3.org/2001/XMLSchema#string

Yiming Deng

http://www.w3.org/2001/XMLSchema#string

P2860

Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity

Reduced H3K27me3 and DNA hypomethylation are major drivers of gene expression in K27M mutant pediatric high-grade gliomas

K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas

PCGF homologs, CBX proteins, and RYBP define functionally distinct PRC1 family complexes

Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas

RYBP-PRC1 complexes mediate H2A ubiquitylation at polycomb target sites independently of PRC2 and H3K27me3

EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency

Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein

Targeting EZH2 in cancer

Polycomb protein family member CBX7 plays a critical role in cancer progression

P2888

s41467-018-04455-7

P304

2080

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/S41467-018-04455-7

http://www.w3.org/2001/XMLSchema#string

P407

English

P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Xiaojun Ren

P577

2018-05-25T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P6179

1104185745

http://www.w3.org/2001/XMLSchema#string

P698

29802243

http://www.w3.org/2001/XMLSchema#string

P921

diffuse intrinsic pontine glioma

P932

5970213

http://www.w3.org/2001/XMLSchema#string

Live-cell single-molecule dynamics of PcG proteins imposed by the DIPG H3.3K27M mutation.

about

P2860

P2860

Live-cell single-molecule dynamics of PcG proteins imposed by the DIPG H3.3K27M mutation.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P2888

P304

P31

P356

P407

P433

P478

P50

P577

P6179

P698

P921

P932

P356

P1433

P1476

P2093

P2860

P2888

P304

P31

P356

P407

P433

P478

P50

P577

P6179

P698

P921

P932