Role of Optineurin in the Mitochondrial Dysfunction: Potential Implications in Neurodegenerative Diseases and Cancer.

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Role of Optineurin in the Mitochondrial Dysfunction: Potential Implications in Neurodegenerative Diseases and Cancer.

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2018 nî lūn-bûn

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2018年の論文

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年學術文章

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2018年學術文章

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2018年學術文章

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name

Role of Optineurin in the Mito ...... enerative Diseases and Cancer.

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Role of Optineurin in the Mito ...... enerative Diseases and Cancer.

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Item

label

Role of Optineurin in the Mito ...... enerative Diseases and Cancer.

@en

Role of Optineurin in the Mito ...... enerative Diseases and Cancer.

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Role of Optineurin in the Mito ...... enerative Diseases and Cancer.

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Role of Optineurin in the Mito ...... enerative Diseases and Cancer.

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P1476

Role of Optineurin in the Mito ...... enerative Diseases and Cancer.

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Emmanuel Laplantine

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Pierre Génin

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Robert Weil

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Shannel Curic

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P275

Creative Commons Attribution 4.0 International

P2860

PINK1 is selectively stabilized on impaired mitochondria to activate Parkin

Guidelines for the use and interpretation of assays for monitoring autophagy

Nix is a selective autophagy receptor for mitochondrial clearance

Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65

Ubiquitin is phosphorylated by PINK1 to activate parkin

PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

The PINK1/Parkin-mediated mitophagy is compromised by PD-associated mutations

Parkin mediates neuroprotection through activation of IkappaB kinase/nuclear factor-kappaB signaling

The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy

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1243

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scholarly article

review article

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10.3389/FIMMU.2018.01243

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P478

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P577

2018-06-19T00:00:00Z

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P698

29971063

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P932

6018216

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