Promoter hypermethylation of the RB1 gene in glioblastomas. - Wikidata - wikimedia - TriplyDB

Promoter hypermethylation of the RB1 gene in glioblastomas.

Promoter hypermethylation of the RB1 gene in glioblastomas.

http://www.wikidata.org/entity/Q55474611

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Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma Recent advances in the molecular understanding of glioblastoma Common stemness regulators of embryonic and cancer stem cells The retinoblastoma gene and its product are targeted by ICBP90: a key mechanism in the G1/S transition during the cell cycle DNA methylation in glioblastoma: impact on gene expression and clinical outcome Genetic Mutations and Epigenetic Modifications: Driving Cancer and Informing Precision Medicine.Non-promoter hypermethylation of zygote arrest 1 (ZAR1) in human brain tumors.Gain of DNA methylation is enhanced in the absence of CTCF at the human retinoblastoma gene promoter.DNA hypermethylation profiles associated with glioma subtypes and EZH2 and IGFBP2 mRNA expression.DNA methylation-mediated silencing of nonsteroidal anti-inflammatory drug-activated gene (NAG-1/GDF15) in glioma cell lines Comparative methylome analysis identifies new tumour subtypes and biomarkers for transformation of nephrogenic rests into Wilms tumour Two independent epigenetic biomarkers predict survival in neuroblastoma MethHC: a database of DNA methylation and gene expression in human cancer.Clinical stratification of glioblastoma based on alterations in retinoblastoma tumor suppressor protein (RB1) and association with the proneural subtype Genetic pathways to primary and secondary glioblastoma Molecular pathogenesis of pediatric astrocytic tumors.Pathology and molecular genetics of astrocytic gliomas.DNA Methylation and Somatic Mutations Converge on the Cell Cycle and Define Similar Evolutionary Histories in Brain Tumors A Tox21 Approach to Altered Epigenetic Landscapes: Assessing Epigenetic Toxicity Pathways Leading to Altered Gene Expression and Oncogenic Transformation In Vitro Molecular biology of human gliomas.Mechanisms of disease: genetic predictors of response to treatment in brain tumors.Intratumoral Heterogeneity of the Epigenome.Loss of Rb1 in the gastrointestinal tract of Apc1638N mice promotes tumors of the cecum and proximal colon.Epithelial and pseudoepithelial differentiation in glioblastoma and gliosarcoma: a comparative morphologic and molecular genetic study.Epigenetic changes in gliomas.Molecular epigenetics and genetics in neuro-oncology.Glioblastoma Multiforme Oncogenomics and Signaling Pathways.PDGFRα depletion attenuates glioblastoma stem cells features by modulation of STAT3, RB1 and multiple oncogenic signals Epigenetics of neurological cancers.Epigenetic aberrations and therapeutic implications in gliomas.Paediatric and adult glioblastoma: multiform (epi)genomic culprits emerge.Loss of heterozygosity analysis in malignant gliomas.Targeted brain tumor treatment-current perspectives Unraveling the glioma epigenome: from molecular mechanisms to novel biomarkers and therapeutic targets.The good, the bad and the ugly: epigenetic mechanisms in glioblastoma.Classification of subpopulations of cells within human primary brain tumors by single cell gene expression profiling.CpG island methylation status and mutation analysis of the RB1 gene essential promoter region and protein-binding pocket domain in nervous system tumours Methylated tumor-specific DNA as a plasma biomarker in patients with glioma.Glioblastoma: pathology, molecular mechanisms and markers.Microarray-based analysis of gene regulation by transcription factors and microRNAs in glioma.

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Promoter hypermethylation of the RB1 gene in glioblastomas.

http://www.wikidata.org/entity/Q55474611

description

2001 nî lūn-bûn

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2001年の論文

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2001年学术文章

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2001年学术文章

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2001年学术文章

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2001年学术文章

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2001年学术文章

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2001年学术文章

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2001年學術文章

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2001年學術文章

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name

Promoter hypermethylation of the RB1 gene in glioblastomas.

@en

Promoter hypermethylation of the RB1 gene in glioblastomas.

@nl

type

label

Promoter hypermethylation of the RB1 gene in glioblastomas.

@en

Promoter hypermethylation of the RB1 gene in glioblastomas.

@nl

prefLabel

Promoter hypermethylation of the RB1 gene in glioblastomas.

@en

Promoter hypermethylation of the RB1 gene in glioblastomas.

@nl

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LABINVEST.3780213

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Laboratory Investigation

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Promoter hypermethylation of the RB1 gene in glioblastomas.

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Kleihues P

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Nakamura M

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Ohgaki H

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Yonekawa Y

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P2860

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

The retinoblastoma protein and cell cycle control

Rb function in cell-cycle regulation and apoptosis.

Molecular mechanisms of oncogenic mutations in tumors from patients with bilateral and unilateral retinoblastoma.

The role of p16-cyclin d/CDK-pRb pathway in the tumorigenesis of endometrioid-type endometrial carcinoma

PTEN (MMAC1) mutations are frequent in primary glioblastomas (de novo) but not in secondary glioblastomas.

Human retinoblastoma susceptibility gene: cloning, identification, and sequence.

Subsets of glioblastoma multiforme defined by molecular genetic analysis.

Molecular genetic correlates of p16, cdk4, and pRb immunohistochemistry in glioblastomas.

Primitive neuroectodermal tumors after prophylactic central nervous system irradiation in children. Association with an activated K-ras gene.

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