about
TORC1 promotes phosphorylation of ribosomal protein S6 via the AGC kinase Ypk3 in Saccharomyces cerevisiaePCK2 activation mediates an adaptive response to glucose depletion in lung cancerUpregulation of a basolateral FXR-dependent bile acid efflux transporter OSTalpha-OSTbeta in cholestasis in humans and rodentsA new xenobiotic-induced mouse model of sclerosing cholangitis and biliary fibrosisSide chain structure determines unique physiologic and therapeutic properties of norursodeoxycholic acid in Mdr2-/- mice.The role of osteopontin and tumor necrosis factor alpha receptor-1 in xenobiotic-induced cholangitis and biliary fibrosis in miceCharacterization of HULC, a novel gene with striking up-regulation in hepatocellular carcinoma, as noncoding RNA.Bile acids trigger cholemic nephropathy in common bile-duct-ligated mice.Lessons from the toxic bile concept for the pathogenesis and treatment of cholestatic liver diseases.ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1.Primary sclerosing cholangitis--the arteriosclerosis of the bile duct?Fibroblast growth factor 21 is induced upon cardiac stress and alters cardiac lipid homeostasis.Analysis of acetylation stoichiometry suggests that SIRT3 repairs nonenzymatic acetylation lesions.Lysosomal Acid Lipase Hydrolyzes Retinyl Ester and Affects Retinoid TurnoverFarnesoid X receptor critically determines the fibrotic response in mice but is expressed to a low extent in human hepatic stellate cells and periductal myofibroblasts.Nucleocytosolic depletion of the energy metabolite acetyl-coenzyme a stimulates autophagy and prolongs lifespan.New insights into autoimmune cholangitis through animal models.Bile acids as regulators of hepatic lipid and glucose metabolism.Targeting nuclear bile acid receptors for liver disease.Primary sclerosing cholangitis: new approaches to diagnosis, surveillance and treatment.Alterations in lipid metabolism mediate inflammation, fibrosis, and proliferation in a mouse model of chronic cholestatic liver injury.Potential of nor-Ursodeoxycholic Acid in Cholestatic and Metabolic Disorders.Adipose triglyceride lipase activity is inhibited by long-chain acyl-coenzyme A.G0/G1 Switch Gene 2 Regulates Cardiac Lipolysis.Acetylation dynamics and stoichiometry in Saccharomyces cerevisiaeDifferential effects of norUDCA and UDCA in obstructive cholestasis in miceRole of hepatic phospholipids in development of liver injury in Mdr2 (Abcb4) knockout mice.Coordinated induction of bile acid detoxification and alternative elimination in mice: role of FXR-regulated organic solute transporter-alpha/beta in the adaptive response to bile acids.Selective Activation of Nuclear Bile Acid Receptor FXR in the Intestine Protects Mice Against Cholestasis98 DIFFERENTIAL EFFECTS OF NORUDCA AND UDCA IN THE TREATMENT OF FATTY LIVER AND ARTERIOSCLEROSIS IN WESTERN CHOW-FED APOE KNOCK OUT MICE125 SIDE CHAIN MODIFIED BILE ACIDS MODULATE ENDOPLASMIC RETICULUM STRESS IN MDR2−/− MICE IN VIVO AND BILE DUCT EPITHELIAL CELLS IN VITROValidated Comprehensive Analytical Method for Quantification of Coenzyme A Activated Compounds in Biological Tissues by Online Solid-Phase Extraction LC/MS/MS[5] ABSENCE OF FXR PROTECTS MICE FROM BILE-INFARCTS IN BILIARY OBSTRUCTION BY REDUCTION OF BILE ACID-INDEPENDENT BILE FLOW: IMPLICATIONS FOR TARGETING FXR IN TREATMENT OF CHOLESTASIS?[48] RETENTION OF TOXIC BILE ACIDS ACTIVATE THE MTOR, P70S6K/RPS6 SIGNALING PATHWAY IN MOUSE MODELS OF CHOLESTATIC LIVER INJURY[307] TNFo AND LPS BUT NOT BILE ACIDS PLAY A KEY ROLE IN THE INDUCTION OF REACTIVE PHENOTYPE IN BILE DUCT EPITHELIAL CELLS IN VITRO320 3.5-Diethoxycarbonyl-1.4-dihydrocollidine (DDC) feeding induces cholestasis, chronic inflammatory bile duct damage and biliary fibrosis in mice62 Common bile-duct-ligation of FXR knockout mice results in severe hepatic steatosis due to enhancement in lipogenic gene expression321 Role of nuclear bile acid receptor FXR in regulation of bile acid detoxification and organic solute transporter (OST-α/β) expression in bile acid-fed mice94 Transcriptional profiling of MDR2 knockout (MDR2−/−) mice treated with NOR-UDCA reveals global anti-inflammatory and anti-fibrotic effects
P50
Q27933998-2B3C3126-E7C6-4B11-8415-ECF1A68E81D8Q28235954-805E36E2-8467-463F-A905-023007A81E91Q28292663-44E09D97-E6A2-423A-9D2F-EDE47BA987B3Q30479829-928FEFE0-E365-473F-9AF4-636149E5B7A6Q30535328-67800C8F-B268-4F80-833C-2BBF5CFAB3F6Q30613139-84EA646F-C44E-4D4A-A05E-7A5857C14517Q33269991-17EA9FD3-27CE-4FBA-829A-4D1EE2B65D8CQ34037360-4BBE1651-7AFE-4AB9-9C59-838B45B67B80Q34657625-DC844DE9-2357-43D1-B00B-0231B900A20FQ35630386-A5B7510E-5272-4120-8D5F-A059330E0C8CQ35632527-5070BE2D-17F7-4FF1-9DF3-D379094EA5BAQ36196772-6571805C-8F8B-4A14-8A12-30A9A2E85C1AQ36270948-21DDE999-FB1D-4E34-809D-B9D47ACF25B5Q37242465-278ABC31-AD31-4074-A9F1-47F4CD61CB19Q37462634-E46C3A96-2E66-4AC3-A2C0-F3EADE88A06AQ37706462-02C16821-39BB-4EBF-892B-2FECBB244557Q37749294-24BA04DB-E107-4E13-9178-3D058C48D591Q37749352-E5A983AC-3A00-4F08-A1EB-48A5D80D5D9FQ37892293-8F8411BE-834D-4309-A91C-3CFCE6F2D0C8Q38053018-39803547-7D63-48D0-B662-26D0D60287D8Q38331124-1C55B7C5-2EC7-407E-98BC-DA6FD665BEA9Q38516783-CF967A30-6E4E-4852-9109-F44DD00BC6FFQ38786661-BC28E738-61EC-463E-B23E-63595A27FB4EQ38836823-1D040CB6-193D-4016-88CC-AA5A5329A369Q39674804-92ED2BC0-FAC5-4FFB-B3B1-9507D0139D5CQ40606268-A461DB34-4705-4E9E-90BB-3A769506AB7EQ46646328-8BB7C022-196F-4CCE-96B3-64675E18915BQ46853058-12169E02-9867-4F0E-AA76-5F68195FFB82Q59515904-82FA9F0C-2A18-4929-B34B-70D8C04007FFQ59515908-B0BA1517-B5C2-4CB9-A569-030A41E2032FQ59515910-5E62791E-4750-4F2A-B2EF-A2C563915888Q59515912-C2EC42B5-B4D1-42EE-A1D0-8E4A8B275E08Q59515915-2DF17FE3-B079-4050-BFC4-A9038D88C1E7Q59515919-2A582D6C-CA24-4AC4-BEF8-D8BBACD2E9DDQ59515922-5009016D-C1AA-4342-9420-331E11703820Q59515926-EA052AAB-D31F-4EC5-BAAF-538079774D47Q59515928-5FDA37FB-D413-45B0-B785-1B63ECFC15E1Q59515932-181F953D-44DF-4BE8-9D81-E3CE5613FF50Q59515935-3BA19065-0077-439A-B965-3960DBD2B44C
P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Tarek Moustafa
@ast
Tarek Moustafa
@en
Tarek Moustafa
@es
Tarek Moustafa
@nl
Tarek Moustafa
@sl
type
label
Tarek Moustafa
@ast
Tarek Moustafa
@en
Tarek Moustafa
@es
Tarek Moustafa
@nl
Tarek Moustafa
@sl
prefLabel
Tarek Moustafa
@ast
Tarek Moustafa
@en
Tarek Moustafa
@es
Tarek Moustafa
@nl
Tarek Moustafa
@sl
P106
P21
P31
P496
0000-0002-6755-4687