about
Caspase-8 specificity probed at subsite S(4): crystal structure of the caspase-8-Z-DEVD-cho complexInsight into host cell carbohydrate-recognition by human and porcine rotavirus from crystal structures of the virion spike associated carbohydrate-binding domain (VP8*)Slow diffusion of lactose out of galectin-3 crystals monitored by X-ray crystallography: possible implications for ligand-exchange protocolsEffects on sialic acid recognition of amino acid mutations in the carbohydrate-binding cleft of the rotavirus spike proteinGalectin inhibitory disaccharides promote tumour immunity in a breast cancer modelTaloside inhibitors of galectin-1 and galectin-3Investigation into the feasibility of thioditaloside as a novel scaffold for galectin-3-specific inhibitorsGalectin-3 interactions with glycosphingolipidsStructural characterization of human galectin-4 C-terminal domain: elucidating the molecular basis for recognition of glycosphingolipids, sulfated saccharides and blood group antigensSubstantial Receptor-induced Structural Rearrangement of Rotavirus VP8*: Potential Implications for Cross-Species InfectionFunctional and structural characterization of a heparanaseGalectin-3-Binding Glycomimetics that Strongly Reduce Bleomycin-Induced Lung Fibrosis and Modulate Intracellular Glycan RecognitionA Selective Galactose-Coumarin-Derived Galectin-3 Inhibitor Demonstrates Involvement of Galectin-3-glycan Interactions in a Pulmonary Fibrosis ModelThe macrophage-inducible C-type lectin, mincle, is an essential component of the innate immune response to Candida albicansRole of pentraxin 3 in shaping arthritogenic alphaviral disease: from enhanced viral replication to immunomodulation.Thiodigalactoside inhibits murine cancers by concurrently blocking effects of galectin-1 on immune dysregulation, angiogenesis and protection against oxidative stress.Crystallization and preliminary X-ray diffraction analysis of the sialic acid-binding domain (VP8*) of porcine rotavirus strain CRW-8.Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of the VP8* carbohydrate-binding protein of the human rotavirus strain Wa.Crystallization and preliminary crystallographic analysis of recombinant human galectin-1.Crystallization and preliminary X-ray diffraction analysis of the carbohydrate-recognizing domain (VP8*) of bovine rotavirus strain NCDVRelative roles of GM1 ganglioside, N-acylneuraminic acids, and α2β1 integrin in mediating rotavirus infection.Galectin-1 as a potent target for cancer therapy: role in the tumor microenvironment.Carbohydrate recognition by rotaviruses.Galectin-3 inhibitors: a patent review (2008-present).Structural characterisation of human galectin-4 N-terminal carbohydrate recognition domain in complex with glycerol, lactose, 3'-sulfo-lactose, and 2'-fucosyllactose.STD NMR spectroscopy and molecular modeling investigation of the binding of N-acetylneuraminic acid derivatives to rhesus rotavirus VP8* core.Synthesis of lactosylated glycoclusters and inhibition studies with plant and human lectins.CuAAC synthesis of resorcin[4]arene-based glycoclusters as multivalent ligands of lectins.Crystallization and preliminary X-ray crystallographic analysis of zebrafish prototype galectin Drgal1-L2.Galectin-1 inhibitors and their potential therapeutic applications: a patent review.Redox state influence on human galectin-1 function.Structure-based rationale for differential recognition of lacto- and neolacto- series glycosphingolipids by the N-terminal domain of human galectin-8Protein subtype-targeting through ligand epimerization: talose-selectivity of galectin-4 and galectin-8.Specificity and affinity of neuraminic acid exhibited by canine rotavirus strain K9 carbohydrate-binding domain (VP8*).Characterisation of oxidized recombinant human galectin-1.Crystallization and preliminary X-ray diffraction studies of FHA domains of Dun1 and Rad53 protein kinasesA crystallographic re-investigation into the structure of Streptomyces griseus proteinase A reveals an acyl-enzyme intermediateLactulose as a novel template for anticancer drug development targeting galectinsStructure-Based Design of a Monosaccharide Ligand Targeting Galectin-8Linear triazole-linked pseudo oligogalactosides as scaffolds for galectin inhibitor development
P50
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P50
description
hulumtuese
@sq
onderzoeker
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researcher
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հետազոտող
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name
Helen Blanchard
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Helen Blanchard
@en
Helen Blanchard
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Helen Blanchard
@nl
Helen Blanchard
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type
label
Helen Blanchard
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Helen Blanchard
@en
Helen Blanchard
@es
Helen Blanchard
@nl
Helen Blanchard
@sl
prefLabel
Helen Blanchard
@ast
Helen Blanchard
@en
Helen Blanchard
@es
Helen Blanchard
@nl
Helen Blanchard
@sl
P106
P1153
56257195200
P21
P31
P496
0000-0003-3372-5027