about
IL-18 attenuates experimental choroidal neovascularization as a potential therapy for wet age-related macular degenerationActivation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes.Adenylate cyclase toxin from Bordetella pertussis synergizes with lipopolysaccharide to promote innate interleukin-10 production and enhances the induction of Th2 and regulatory T cells.NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen componentsPneumolysin activates the NLRP3 inflammasome and promotes proinflammatory cytokines independently of TLR4.The shape and size of hydroxyapatite particles dictate inflammatory responses following implantation.Polymyxin B inadequately quenches the effects of contaminating lipopolysaccharide on murine dendritic cells.Inhibitor of apoptosis proteins (IAPs) and their antagonists regulate spontaneous and tumor necrosis factor (TNF)-induced proinflammatory cytokine and chemokine production.Relative contribution of Th1 and Th17 cells in adaptive immunity to Bordetella pertussis: towards the rational design of an improved acellular pertussis vaccine.Mucosal vaccination against serogroup B meningococci: induction of bactericidal antibodies and cellular immunity following intranasal immunization with NadA of Neisseria meningitidis and mutants of Escherichia coli heat-labile enterotoxin.Multivalent presentation of MPL by porous silicon microparticles favors T helper 1 polarization enhancing the anti-tumor efficacy of doxorubicin nanoliposomes.Effects of cholera toxin on innate and adaptive immunity and its application as an immunomodulatory agent.Molecules of infectious agents as immunomodulatory drugs.Necroptosis suppresses inflammation via termination of TNF- or LPS-induced cytokine and chemokine productionMemory Th1 Cells Are Protective in Invasive Staphylococcus aureus Infection.Generation of improved mucosal vaccines by induction of innate immunity.A Common Variant in the Adaptor Mal Regulates Interferon Gamma Signaling.Delivery systems and adjuvants for oral vaccines.Targeted nasal vaccination provides antibody-independent protection against Staphylococcus aureusThe Vaccine Adjuvant Chitosan Promotes Cellular Immunity via DNA Sensor cGAS-STING-Dependent Induction of Type I InterferonsUptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome.Nlrp-3-driven interleukin 17 production by γδT cells controls infection outcomes during Staphylococcus aureus surgical site infection.A novel immunomodulatory hemocyanin from the limpet Fissurella latimarginata promotes potent anti-tumor activity in melanoma.The role of TLRs, NLRs, and RLRs in mucosal innate immunity and homeostasis.The role of inflammasomes in the immunostimulatory effects of particulate vaccine adjuvants.Trends in vaccine adjuvants.Recent advances in microparticle and nanoparticle delivery vehicles for mucosal vaccination.The role of CD103⁺ dendritic cells in the intestinal mucosal immune system.Immunomodulatory properties of the vaccine adjuvant alum.Harnessing the antibacterial and immunological properties of mucosal-associated invariant T cells in the development of novel oral vaccines against enteric infections.Delivery strategies to enhance oral vaccination against enteric infections.Interleukin 33: an innate alarm for adaptive responses beyond Th2 immunity-emerging roles in obesity, intestinal inflammation, and cancer.Extracellular cathepsin S and intracellular caspase 1 activation are surrogate biomarkers of particulate-induced lysosomal disruption in macrophagesAutophagy regulates IL-23 secretion and innate T cell responses through effects on IL-1 secretion.A novel adjuvanted capsule based strategy for oral vaccination against infectious diarrhoeal pathogens.Helminth Products Protect against Autoimmunity via Innate Type 2 Cytokines IL-5 and IL-33, Which Promote Eosinophilia.Granzyme B-dependent proteolysis acts as a switch to enhance the proinflammatory activity of IL-1α.A crucial role for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis.Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity.The stability and immunogenicity of a protein antigen encapsulated in biodegradable microparticles based on blends of lactide polymers and polyethylene glycol.
P50
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P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Ed C Lavelle
@nl
Ed C Lavelle
@sl
Ed C. Lavelle
@en
Ed C. Lavelle
@es
type
label
Ed C Lavelle
@nl
Ed C Lavelle
@sl
Ed C. Lavelle
@en
Ed C. Lavelle
@es
prefLabel
Ed C Lavelle
@nl
Ed C Lavelle
@sl
Ed C. Lavelle
@en
Ed C. Lavelle
@es
P106
P1153
7004514926
P31
P496
0000-0002-3167-1080