about
Rapid copper acquisition by developing murine mesothelioma: decreasing bioavailable copper slows tumor growth, normalizes vessels and promotes T cell infiltrationLipid-laden partially-activated plasmacytoid and CD4(-)CD8α(+) dendritic cells accumulate in tissues in elderly miceMesothelioma tumor cells modulate dendritic cell lipid content, phenotype and functionThe "Trojan Horse" approach to tumor immunotherapy: targeting the tumor microenvironment.Cross-presentation of tumour antigens: evaluation of threshold, duration, distribution and regulation.Blood-brain barrier dysfunction developed during normal aging is associated with inflammation and loss of tight junctions but not with leukocyte recruitment.Rapid dendritic cell recruitment is a hallmark of the acute inflammatory response at mucosal surfacesTumor growth or regression: powered by inflammation.Human mesothelioma induces defects in dendritic cell numbers and antigen-processing function which predict survival outcomesMurine mesothelioma induces locally-proliferating IL-10(+)TNF-α(+)CD206(-)CX3CR1(+) M3 macrophages that can be selectively depleted by chemotherapy or immunotherapy.Are macrophages, myeloid derived suppressor cells and neutrophils mediators of local suppression in healthy and cancerous tissues in aging hosts?IL-2/CD40-activated macrophages rescue age and tumor-induced T cell dysfunction in elderly mice.Targeting macrophages rescues age-related immune deficiencies in C57BL/6J geriatric mice.Aging and cancer: The role of macrophages and neutrophils.A review of the importance of immune responses in luminal B breast cancer.Chemotherapy broadens the range of tumor antigens seen by cytotoxic CD8(+) T cells in vivo.Modulation of dendritic cell and T cell cross-talk during aging: The potential role of checkpoint inhibitory molecules.Intratumoral interleukin-2/agonist CD40 antibody drives CD4+ -independent resolution of treated-tumors and CD4+ -dependent systemic and memory responses.Local effector failure in mesothelioma is not mediated by CD4+ CD25+ T-regulator cells.Deliberately provoking local inflammation drives tumors to become their own protective vaccine site.Functional endogenous cytotoxic T lymphocytes are generated to multiple antigens co-expressed by progressing tumors; after intra-tumoral IL-2 therapy these effector cells eradicate established tumors.Turning the tumor microenvironment into a self vaccine site.Development of the airway intraepithelial dendritic cell network in the rat from class II major histocompatibility (Ia)-negative precursors: differential regulation of Ia expression at different levels of the respiratory tract.CD40-activated B cells contribute to mesothelioma tumor regression.Dendritic cells infected with a vaccinia virus interleukin-2 vector secrete high levels of IL-2 and can become efficient antigen presenting cells that secrete high levels of the immunostimulatory cytokine IL-12.Aged neutrophils accumulate in lymphoid tissues from healthy elderly mice and infiltrate T and B cell zones.Effect of ozone exposure on alveolar macrophage-mediated immunosuppressive activity in ratsBasic science funding in Australia: lessons from the EU
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P50
description
hulumtuese
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Delia J Nelson
@nl
Delia J Nelson
@sl
Delia J. Nelson
@en
Delia J. Nelson
@es
type
label
Delia J Nelson
@nl
Delia J Nelson
@sl
Delia J. Nelson
@en
Delia J. Nelson
@es
prefLabel
Delia J Nelson
@nl
Delia J Nelson
@sl
Delia J. Nelson
@en
Delia J. Nelson
@es
P106
P1153
7404328849
P21
P31
P496
0000-0002-8698-5300