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The expression levels of prolyl oligopeptidase responds not only to neuroinflammation but also to systemic inflammation upon liver failure in rat models and cirrhotic patientsBlocking NMDA receptors delays death in rats with acute liver failure by dual protective mechanisms in kidney and brain.Non invasive blood flow measurement in cerebellum detects minimal hepatic encephalopathy earlier than psychometric testsThe PHES battery does not detect all cirrhotic patients with early neurological deficits, which are different in different patientsBacterial plate assays and electrochemical methods: an efficient tandem for evaluating the ability of catechol-thioether metabolites of MDMA ("ecstasy") to induce toxic effects through redox-cycling.Urinary KIM-1, NGAL and L-FABP for the diagnosis of AKI in patients with acute coronary syndrome or heart failure undergoing coronary angiography.Rats with mild bile duct ligation show hepatic encephalopathy with cognitive and motor impairment in the absence of cirrhosis: effects of alcohol ingestion.Relationship between insulin resistance, inflammation and liver cell apoptosis in patients with severe obesity.Nitric oxide promotes strong cytotoxicity of phenolic compounds against Escherichia coli: the influence of antioxidant defenses.Reduced white matter microstructural integrity correlates with cognitive deficits in minimal hepatic encephalopathy.Metabolism of cyclic GMP in non-alcoholic fatty liver disease in morbid obesity.Real-time cytometric assay of nitric oxide and superoxide interaction in peripheral blood monocytes: A no-wash, no-lyse kinetic method.New Escherichia coli WP2 tester strains highly sensitive to reversion by oxidative mutagens.Altered postural control and stability in cirrhotic patients with minimal hepatic encephalopathy correlate with cognitive deficits.Focal cortical damage parallels cognitive impairment in minimal hepatic encephalopathy.Increased mutability by oxidative stress in OxyR-deficient Escherichia coli and Salmonella typhimurium cells: clonal occurrence of the mutants during growth on nonselective media.Influence of the processing of MucA protein on the reversion of the frameshift hisD3052 and the base substitution hisG46 mutations by chemical mutagens in Salmonella typhimurium.Quinolone action in Escherichia coli cells carrying gyrA and gyrB mutations.Specificity of spontaneous and t-butyl hydroperoxide-induced mutations in delta oxyR strains of Escherichia coli differing with respect to the SOS mutagenesis proficiency and to the MutY and MutM functions.Detection of oxidative mutagens in strains of Escherichia coli deficient in the OxyR or MutY functions: dependence on SOS mutagenesis.Processing of MucA protein is required for spontaneous and benzo[a]pyrene-induced reversion of the Escherichia coli trpA23 missense mutation by G.C-T.A transversions: effect of a deficiency in the MutY DNA glycosylase.Induction of SOS-independent mutations by benzo[a]pyrene treatment in Escherichia coli cells deficient in MutY or MutM DNA glycosylases: possible role of oxidative lesionsMutagenicity of 80 chemicals in Escherichia coli tester strains IC203, deficient in OxyR, and its oxyR(+) parent WP2 uvrA/pKM101: detection of 31 oxidative mutagensDetection of oxidative mutagenesis by isoniazid and other hydrazine derivatives in Escherichia coli WP2 tester strain IC203, deficient in OxyR: strong protective effects of rat liver S9IL-6 and IL-18 in blood may discriminate cirrhotic patients with and without minimal hepatic encephalopathyContribution of hyperammonemia and inflammatory factors to cognitive impairment in minimal hepatic encephalopathyEarly biomarkers of acute kidney failure after heart angiography or heart surgery in patients with acute coronary syndrome or acute heart failure3-nitro-tyrosine as a peripheral biomarker of minimal hepatic encephalopathy in patients with liver cirrhosisPatients with minimal hepatic encephalopathy show impaired mismatch negativity correlating with reduced performance in attention testsUrinary Klotho measured by ELISA as an early biomarker of acute kidney injury in patients after cardiac surgery or coronary angiographyAlterations in adipocytokines and cGMP homeostasis in morbid obesity patients reverse after bariatric surgeryIs cognitive impairment in cirrhotic patients due to increased peroxynitrite and oxidative stress?The Erythrocytic Hypothesis of Brain Energy Crisis in Sporadic Alzheimer Disease: Possible Consequences and Supporting Evidence
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հետազոտող
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Amparo Urios
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Amparo Urios
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Amparo Urios
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0000-0003-2699-7040