RNA Polymerase II Is Required for RNAi-Dependent Heterochromatin Assembly
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The death-associated protein DAXX is a novel histone chaperone involved in the replication-independent deposition of H3.3RNA and transcriptional modulation of gene expressionCentromere RNA is a key component for the assembly of nucleoproteins at the nucleolus and centromereThe piRNA Pathway Guards the Germline Genome Against Transposable ElementsChromosome boundary elements and regulation of heterochromatin spreadingCentromeric heterochromatin assembly in fission yeast--balancing transcription, RNA interference and chromatin modificationOrigins and Mechanisms of miRNAs and siRNAsTranscription and RNAi in heterochromatic gene silencingArgonaute-1 directs siRNA-mediated transcriptional gene silencing in human cellsSmall RNAs in transcriptional gene silencing and genome defenceRNA interference and heterochromatin assemblyThe RFTS domain of Raf2 is required for Cul4 interaction and heterochromatin integrity in fission yeastRNA-directed epigenetic silencing of Periostin inhibits cell motilityA chromatin landmark and transcription initiation at most promoters in human cellsPolIVb influences RNA-directed DNA methylation independently of its role in siRNA biogenesisA complex small RNA repertoire is generated by a plant/fungal-like machinery and effected by a metazoan-like Argonaute in the single-cell human parasite Toxoplasma gondii.Two-step recruitment of RNA-directed DNA methylation to tandem repeats.High-resolution mapping reveals links of HP1 with active and inactive chromatin components.The lin-35/Rb and RNAi pathways cooperate to regulate a key cell cycle transition in C. elegans.RNA Pol II promotes transcription of centromeric satellite DNA in beetles.Mapping epigenetic mutations in fission yeast using whole-genome next-generation sequencing.Intergenic transcription by RNA polymerase II coordinates Pol IV and Pol V in siRNA-directed transcriptional gene silencing in ArabidopsisA meiosis-specific Spt5 homolog involved in non-coding transcription.Tracking the evolution of 3D gene organization demonstrates its connection to phenotypic divergenceThe DNA/RNA-dependent RNA polymerase QDE-1 generates aberrant RNA and dsRNA for RNAi in a process requiring replication protein A and a DNA helicase.Continuous requirement for the Clr4 complex but not RNAi for centromeric heterochromatin assembly in fission yeast harboring a disrupted RITS complexTranscription-independent functions of an RNA polymerase II subunit, Rpb2, during genome rearrangement in the ciliate, Oxytricha trifallax.RITS-connecting transcription, RNA interference, and heterochromatin assembly in fission yeast.DNA-RNA hybrid formation mediates RNAi-directed heterochromatin formation.The methyltransferase activity of Clr4Suv39h triggers RNAi independently of histone H3K9 methylation.Raf1 Is a DCAF for the Rik1 DDB1-like protein and has separable roles in siRNA generation and chromatin modificationSubunit compositions of the RNA-silencing enzymes Pol IV and Pol V reveal their origins as specialized forms of RNA polymerase IIHeterochromatin protein 1 (HP1) connects the FACT histone chaperone complex to the phosphorylated CTD of RNA polymerase II.Transcription and RNA interference in the formation of heterochromatin.DNA replication, RNAi and epigenetic inheritance.Distinct roles for Sir2 and RNAi in centromeric heterochromatin nucleation, spreading and maintenance.Conserved themes in small-RNA-mediated transposon control.RNA interference in the nucleus: roles for small RNAs in transcription, epigenetics and beyond.Small interfering RNA-producing loci in the ancient parasitic eukaryote Trypanosoma brucei.RNAi-dependent formation of heterochromatin and its diverse functions
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RNA Polymerase II Is Required for RNAi-Dependent Heterochromatin Assembly
description
article publié dans la revue scientifique Science
@fr
im Juli 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific article published in Science
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована в липні 2005
@uk
name
RNA Polymerase II Is Required for RNAi-Dependent Heterochromatin Assembly
@en
RNA Polymerase II Is Required for RNAi-Dependent Heterochromatin Assembly
@nl
type
label
RNA Polymerase II Is Required for RNAi-Dependent Heterochromatin Assembly
@en
RNA Polymerase II Is Required for RNAi-Dependent Heterochromatin Assembly
@nl
prefLabel
RNA Polymerase II Is Required for RNAi-Dependent Heterochromatin Assembly
@en
RNA Polymerase II Is Required for RNAi-Dependent Heterochromatin Assembly
@nl
P2093
P356
P1433
P1476
RNA polymerase II is required for RNAi-dependent heterochromatin assembly
@en
P2093
Derek B Goto
Koichi Furukawa
Robert A Martienssen
Yota Murakami
P304
P356
10.1126/SCIENCE.1114955
P407
P577
2005-06-09T00:00:00Z