about
A brain-specific isoform of mitochondrial apoptosis-inducing factor: AIF2Parkin mediates neuroprotection through activation of IkappaB kinase/nuclear factor-kappaB signalingKCa2 channels activation prevents [Ca2+]i deregulation and reduces neuronal death following glutamate toxicity and cerebral ischemiaEnalapril and moexipril protect from free radical-induced neuronal damage in vitro and reduce ischemic brain injury in mice and ratsEvidence for the involvement of Par-4 in ischemic neuron cell deathBeta(2)-adrenoceptor stimulation enhances latent transforming growth factor-beta-binding protein-1 and transforming growth factor-beta1 expression in rat hippocampus after transient forebrain ischemiaPresenilin-1 mutations sensitize neurons to DNA damage-induced death by a mechanism involving perturbed calcium homeostasis and activation of calpains and caspase-12Bid-induced release of AIF from mitochondria causes immediate neuronal cell deathAdaptive plasticity in tachykinin and tachykinin receptor expression after focal cerebral ischemia is differentially linked to gabaergic and glutamatergic cerebrocortical circuits and cerebrovenular endothelium.Proteomic analysis reveals differences in protein expression in spheroid versus monolayer cultures of low-passage colon carcinoma cells.Inhibition of the AIF/CypA complex protects against intrinsic death pathways induced by oxidative stress.Subcellular expression and neuroprotective effects of SK channels in human dopaminergic neuronsCellular and molecular mechanisms underlying perturbed energy metabolism and neuronal degeneration in Alzheimer's and Parkinson's diseases.Apoptotic and antiapoptotic mechanisms in stroke.Neurodegenerative disorders and ischemic brain diseases.Glutathione peroxidase 4 senses and translates oxidative stress into 12/15-lipoxygenase dependent- and AIF-mediated cell death.Structure-activity relationships by interligand NOE-based design and synthesis of antiapoptotic compounds targeting Bid.Current concepts in chronic inflammatory diseases: Interactions between microbes, cellular metabolism, and inflammation.The metalloprotease-disintegrin ADAM8 contributes to temozolomide chemoresistance and enhanced invasiveness of human glioblastoma cells.Protective Roles for Potassium SK/K(Ca)2 Channels in Microglia and Neurons.Targeting Bid to prevent programmed cell death in neurons.Egr-1 regulates expression of the glial scar component phosphacan in astrocytes after experimental stroke.Therapeutic targeting of oxygen-sensing prolyl hydroxylases abrogates ATF4-dependent neuronal death and improves outcomes after brain hemorrhage in several rodent models.BID links ferroptosis to mitochondrial cell death pathways.Statins--increasing or reducing the risk of Parkinson's disease?A Small-Molecule Inhibitor of Bax and Bak Oligomerization Prevents Genotoxic Cell Death and Promotes Neuroprotection.Activation of SK2 channels preserves ER Ca²⁺ homeostasis and protects against ER stress-induced cell death.Central inhibition of IKKβ/NF-κB signaling attenuates high-fat diet-induced obesity and glucose intolerance.SK channel activation modulates mitochondrial respiration and attenuates neuronal HT-22 cell damage induced by H2O2.Pifithrin-α provides neuroprotective effects at the level of mitochondria independently of p53 inhibition.The serine protease inhibitor TLCK attenuates intrinsic death pathways in neurons upstream of mitochondrial demise.N-acyl derivatives of 4-phenoxyaniline as neuroprotective agents.Novel N-phenyl-substituted thiazolidinediones protect neural cells against glutamate- and tBid-induced toxicity.α1-antitrypsin modulates microglial-mediated neuroinflammation and protects microglial cells from amyloid-β-induced toxicity.SK2 channels regulate mitochondrial respiration and mitochondrial Ca2+ uptake.Small conductance Ca2+-activated K+ channels in the plasma membrane, mitochondria and the ER: Pharmacology and implications in neuronal diseases.Inhibition of Drp1 provides neuroprotection in vitro and in vivo.Impedance measurement for real time detection of neuronal cell death.Bid-mediated mitochondrial damage is a key mechanism in glutamate-induced oxidative stress and AIF-dependent cell death in immortalized HT-22 hippocampal neurons.Bid mediates fission, membrane permeabilization and peri-nuclear accumulation of mitochondria as a prerequisite for oxidative neuronal cell death.
P50
Q24297828-B44B4608-FFA9-4D5D-814B-4F1CD8B1E601Q24297849-9143E715-D4EC-400B-AEDC-72629B05F333Q24607048-8D04FD1D-AFA6-4C69-9BEE-189071573ED6Q28369284-009182DA-6578-4407-A4F6-C7ED57E64078Q28569113-65E8649D-59C6-4121-97CB-A4AE94C83351Q28578783-2CB1008A-79E0-4C5B-B7AF-8E7734439F32Q28586910-DD739D7C-DB77-4283-938A-19111634343AQ30494311-6CC09162-A329-4285-8A0B-59F23CDD6BAFQ31826733-77B845E8-EC45-4E8F-9623-2DA0B6DDBBCFQ33301721-7D78C8A8-15CC-4C6E-8993-FF61D2D956EEQ33694996-85B283C1-E4BA-4533-8063-DD793E52D509Q33695091-C553ABBB-EF82-477E-A074-82754FE140DCQ33836230-C732B712-AA79-49B5-9087-045945DB67BFQ33992385-8EA9A55D-9649-4A4D-9E51-CB6474C2037BQ34230670-4F689204-AA0D-45DF-8683-489A2FC684C0Q34818662-F105DA63-D2D8-4026-94C5-28F43B090FD8Q35033809-13A37B7B-5E2C-4655-907A-C1CBE240A258Q36066845-79A0E266-AC02-4BFC-A237-29B98BA16200Q36288254-EB3DBF48-3C32-4173-B79C-84DE974FA64EQ36421908-2D53CC60-4C9C-49E0-A645-DF023F647CBCQ36639020-51C2294A-0C13-48B4-83AF-CAA6C511AE51Q36734866-062D9720-49DB-4B83-AFC8-B5BE14E62019Q37685941-14BA117C-EA83-4CC2-AC7E-037F88427FEFQ37738992-C2990AF8-D367-4F4A-A345-904960973BC0Q37812781-1D2E4B84-3D56-4D0C-A24D-27C74F8AD0EDQ38432040-13F4F53F-E82D-4331-8829-2B7405BA7BBAQ38818195-E24513AB-9513-480B-BB96-C901EEF7352EQ38915900-C89FC5E7-07D7-4716-BC81-8457AA3670C0Q38921475-DC9A7691-B67B-468D-A0D8-3E27239EA039Q38945300-6FFD620F-3947-47D5-BE55-79CE5EC6E447Q38963931-9B3CBE1C-7319-425D-8646-70DB32268B04Q38973549-B86EC5ED-E6B5-408C-81C8-26356280D5ADQ38992888-74362509-9440-4DD7-8B6D-47A2F449762BQ39125010-6EBC16F2-8721-45D6-BD9F-9238D8792ACAQ39304453-842E966D-7355-4677-B9AB-8EDA30695AD8Q39311997-51D078AA-E809-45B5-818D-86EEC9076663Q39386090-D2286D6E-4793-431C-89B0-223347B312CEQ39465069-2D9FDBDF-A09F-4B7A-A367-DCB6B2693E83Q39670591-DCDFBC60-59EE-4560-BBDC-887822EBA25FQ39766864-09A9FC86-8300-46DB-B100-8B8A54333028
P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Carsten Culmsee
@ast
Carsten Culmsee
@en
Carsten Culmsee
@es
Carsten Culmsee
@nl
Carsten Culmsee
@sl
type
label
Carsten Culmsee
@ast
Carsten Culmsee
@en
Carsten Culmsee
@es
Carsten Culmsee
@nl
Carsten Culmsee
@sl
prefLabel
Carsten Culmsee
@ast
Carsten Culmsee
@en
Carsten Culmsee
@es
Carsten Culmsee
@nl
Carsten Culmsee
@sl
P108
P106
P31
P496
0000-0002-5121-5015