about
Characterization of a novel HMG-CoA lyase enzyme with a dual location in endoplasmic reticulum and cytosolMutations and variants in the cohesion factor genes NIPBL, SMC1A, and SMC3 in a cohort of 30 unrelated patients with Cornelia de Lange syndromeIdentification of multicopy suppressors of cell cycle arrest at the G1-S transition in Saccharomyces cerevisiae.Characterization of splice variants of the genes encoding human mitochondrial HMG-CoA lyase and HMG-CoA synthase, the main enzymes of the ketogenesis pathwayC-terminal end and aminoacid Lys48 in HMG-CoA lyase are involved in substrate binding and enzyme activityTen novel HMGCL mutations in 24 patients of different origin with 3-hydroxy-3-methyl-glutaric aciduriaCPT1c is localized in endoplasmic reticulum of neurons and has carnitine palmitoyltransferase activityRegulation of mitochondrial 3-hydroxy-3-methylglutaryl-coenzyme A synthase protein by starvation, fat feeding, and diabetesCeramides and mitochondrial fatty acid oxidation in obesity.Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance.Regulation of substrate oxidation preferences in muscle by the peptide hormone adropin.Malonyl-CoA mediates leptin hypothalamic control of feeding independent of inhibition of CPT-1aN-cadherin expression is regulated by UTP in schwannoma cells.Hypothalamic ceramide levels regulated by CPT1C mediate the orexigenic effect of ghrelin.Central ceramide-induced hypothalamic lipotoxicity and ER stress regulate energy balanceCarnitine palmitoyltransferase 1C: From cognition to cancer.Hypothalamic regulation of liver and muscle nutrient partitioning by brain-specific carnitine palmitoyltransferase 1C (CPT1C) in male mice.Reduction of Hypothalamic Endoplasmic Reticulum Stress Activates Browning of White Fat and Ameliorates Obesity.Isolation of pluripotent stem cells from human third molar dental pulp.Novel Regulation of the Synthesis of α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Subunit GluA1 by Carnitine Palmitoyltransferase 1C (CPT1C) in the Hippocampus.Two missense point mutations in different alleles in the 3-hydroxy-3-methylglutaryl coenzyme A lyase gene produce 3-hydroxy-3-methylglutaric aciduria in a French patient.Enhanced fatty acid oxidation in adipocytes and macrophages reduces lipid-induced triglyceride accumulation and inflammation.Blattella germanica has two HMG-CoA synthase genes. Both are regulated in the ovary during the gonadotrophic cycle.Astrocytes and oligodendrocytes in grey and white matter regions of the brain metabolize fatty acids.Coordinated expression and activity of 3-hydroxy-3-methylglutaryl coenzyme A synthase and reductase in the fat body of Blattella germanica (L.) during vitellogenesis.Differential effects of central ghrelin on fatty acid metabolism in hypothalamic ventral medial and arcuate nuclei.CDP-choline prevents glutamate-mediated cell death in cerebellar granule neurons.Molecular basis of 3-hydroxy-3-methylglutaric aciduria.Skipping of exon 2 and exons 2 plus 3 of HMG-CoA lyase (HL) gene produces the loss of beta sheets 1 and 2 in the recently proposed (beta-alpha)8 TIM barrel model of HL.Increased inflammation, oxidative stress and mitochondrial respiration in brown adipose tissue from obese mice.Carnitine palmitoyltransferase 1C deficiency causes motor impairment and hypoactivity.Ghrelin Causes a Decline in GABA Release by Reducing Fatty Acid Oxidation in Cortex.Uridine-5'-Triphosphate Partially Blocks Differentiation Signals and Favors a more Repair State in Cultured rat Schwann Cells.The diagnosis of mitochondrial HMG-CoA synthase deficiency.Mediterranean tomato-based sofrito protects against vascular alterations in obese Zucker rats by preserving NO bioavailability.Buccal fat pad, an oral access source of human adipose stem cells with potential for osteochondral tissue engineering: an in vitro study.A single-residue mutation, G203E, causes 3-hydroxy-3-methylglutaric aciduria by occluding the substrate channel in the 3D structural model of HMG-CoA lyase.CPT1C promotes human mesenchymal stem cells survival under glucose deprivation through the modulation of autophagy.Mechanisms of CPT1C-Dependent AMPAR Trafficking EnhancementCPT1C in the ventromedial nucleus of the hypothalamus is necessary for brown fat thermogenesis activation in obesity.
P50
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P50
description
hulumtuese
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Nuria Casals
@ast
Nuria Casals
@en
Nuria Casals
@es
Nuria Casals
@nl
Nuria Casals
@sl
type
label
Nuria Casals
@ast
Nuria Casals
@en
Nuria Casals
@es
Nuria Casals
@nl
Nuria Casals
@sl
prefLabel
Nuria Casals
@ast
Nuria Casals
@en
Nuria Casals
@es
Nuria Casals
@nl
Nuria Casals
@sl
P106
P21
P31
P496
0000-0002-6719-4300