about
Double threading through DNA: NMR structural study of a bis-naphthalene macrocycle bound to a thymine-thymine mismatchA novel Hsp70 inhibitor prevents cell intoxication with the actin ADP-ribosylating Clostridium perfringens iota toxin"One Ring to Bind Them All"-Part II: Identification of Promising G-Quadruplex Ligands by Screening of Cyclophane-Type Macrocycles."One ring to bind them all"-part I: the efficiency of the macrocyclic scaffold for g-quadruplex DNA recognition.Polycyclic azoniahetarenes: assessing the binding parameters of complexes between unsubstituted ligands and G-quadruplex DNA.Selective recognition of pyrimidine-pyrimidine DNA mismatches by distance-constrained macrocyclic bis-intercalatorsVisualizing the quadruplex: from fluorescent ligands to light-up probes.Finding needles in a basestack: recognition of mismatched base pairs in DNA by small molecules.Diazoniapolycyclic ions inhibit the activity of topoisomerase I and the growth of certain tumor cell lines.A common intronic variant of PARP1 confers melanoma risk and mediates melanocyte growth via regulation of MITF.The human mitochondrial transcription factor A is a versatile G-quadruplex binding protein.Macrocyclic DNA-mismatch-binding ligands: structural determinants of selectivity.Diazonia- and tetraazoniapolycyclic cations as motif for quadruplex-DNA ligands.A fluorescent bisanthracene macrocycle discriminates between matched and mismatch-containing DNA.Recognition of homopyrimidine mismatches by distance-constrained macrocyclic bisintercalators.Water-soluble, pH-sensitive fluorescent probes on the basis of acridizinium ions.Relationship between the structure and the DNA binding properties of diazoniapolycyclic duplex- and triplex-DNA binders: efficiency, selectivity, and binding mode.Copper(II)-Controlled Molecular Glue for Mismatched DNA.TWJ-Screen: an isothermal screening assay to assess ligand/DNA junction interactions in vitro.Asymmetric distyrylpyridinium dyes as red-emitting fluorescent probes for quadruplex DNA.Efficient inhibition of human AP endonuclease 1 (APE1) via substrate masking by abasic site-binding macrocyclic ligands.Probing of G-Quadruplex Structures via Ligand-Sensitized Photochemical Reactions in U-Substituted DNAComparative study of affinity and selectivity of ligands targeting abasic and mismatch sites in DNA using a fluorescence-melting assayAggregating distyrylpyridinium dye as a bimodal structural probe for G-quadruplex DNACationic azacryptands as selective three-way DNA junction binding agentsRecognition of G-Quadruplex DNA by Triangular Star-Shaped Compounds: With or Without Side Chains?Recognition of DNA secondary structures: from structure to fluorescent probesSynthesis of mono- and bibrachial naphthalene-based macrocycles with pyrene or ferrocene units for anion detectionLigand-Induced Conformational Changes with Cation Ejection upon Binding to Human Telomeric DNA G-QuadruplexesDual Fluorescence of 2-Methoxyanthracene DerivativesStudies of the fluorescence light-up effect of amino-substituted benzo[b]quinolizinium derivatives in the presence of biomacromolecules9-donor-substituted acridizinium salts: versatile environment-sensitive fluorophores for the detection of biomacromoleculesSynthesis of 6-amino-3,4-dihydroisoquinolinium derivatives by ring-opening reactions of acridizinium ionsN-aryl-9-amino-substituted acridizinium derivatives as fluorescent "light-up" probes for DNA and protein detectionSelective stabilization of triple-helical DNA by diazoniapolycyclic intercalatorsPattern-based sensing of short oligodeoxynucleotides with palladium-dye complexesCombining metallasupramolecular chemistry with dynamic covalent chemistry: synthesis of large molecular cagesTopology-Selective, Fluorescent "Light-Up" Probes for G-Quadruplex DNA Based on Photoinduced Electron TransferInteraction of Functionalized Naphthalenophanes with Abasic Sites in DNA: DNA Cleavage, DNA Cleavage Inhibition, and Formation of Ligand-DNA AdductsStrength in Numbers: Development of a Fluorescence Sensor Array for Secondary Structures of DNA
P50
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P50
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onderzoeker
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հետազոտող
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Anton Granzhan
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Anton Granzhan
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Anton Granzhan
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P106
P1153
9636018200
P21
P31
P496
0000-0002-0424-0461