about
A critical re-assessment of DNA repair gene promoter methylation in non-small cell lung carcinomaPermissive transcriptional activity at the centromere through pockets of DNA hypomethylation.Variable and hierarchical size distribution of L1-retroelement-enriched CENP-A clusters within a functional human neocentromereWheel running and environmental enrichment differentially modify exon-specific BDNF expression in the hippocampus of wild-type and pre-motor symptomatic male and female Huntington's disease mice.Exemplary multiplex bisulfite amplicon data used to demonstrate the utility of Methpat.Condensin I associates with structural and gene regulatory regions in vertebrate chromosomes.Hypermethylation and down-regulation of DLEU2 in paediatric acute myeloid leukaemia independent of embedded tumour suppressor miR-15a/16-1.Epigenetic deregulation in pediatric acute lymphoblastic leukemia.DNA methylation-mediated down-regulation of DNA methyltransferase-1 (DNMT1) is coincident with, but not essential for, global hypomethylation in human placenta.Stability of gene expression and epigenetic profiles highlights the utility of patient-derived paediatric acute lymphoblastic leukaemia xenografts for investigating molecular mechanisms of drug resistance.Investigating the potential role of genetic and epigenetic variation of DNA methyltransferase genes in hyperplastic polyposis syndromeA phase II trial of primary temozolomide in patients with grade III oligodendroglial brain tumorsEvaluation of microRNA expression in patient bone marrow aspirate slides.BAC-based PCR fragment microarray: high-resolution detection of chromosomal deletion and duplication breakpoints.Normal DNA methylation dynamics in DICER1-deficient mouse embryonic stem cellsThe use of DNA from archival dried blood spots with the Infinium HumanMethylation450 array.Validation of DNA methylation biomarkers for diagnosis of acute lymphoblastic leukemia.Paediatric leukaemia DNA methylation profiling using MBD enrichment and SOLiD sequencing on archival bone marrow smearsQuantitative methodology is critical for assessing DNA methylation and impacts on correlation with patient outcomeMethPat: a tool for the analysis and visualisation of complex methylation patterns obtained by massively parallel sequencing.Genome-scale methylation assessment did not identify prognostic biomarkers in oral tongue carcinomasWide-ranging DNA methylation differences of primary trophoblast cell populations and derived cell lines: implications and opportunities for understanding trophoblast function.Reducing the risk of false discovery enabling identification of biologically significant genome-wide methylation status using the HumanMethylation450 array.Atypical Spitzoid neoplasms: a review of potential markers of biological behavior including sentinel node biopsy.Archived Guthrie blood spots as a novel source for quantitative DNA methylation analysis.Exploring the utility of human DNA methylation arrays for profiling mouse genomic DNA.Specific-site methylation of tumour suppressor ANKRD11 in breast cancer.Specific tumour-associated methylation in normal human term placenta and first-trimester cytotrophoblasts.Methylation of the adenomatous polyposis coli (APC) gene in human placenta and hypermethylation in choriocarcinoma cells.Epigenetic silencing of BIM in glucocorticoid poor-responsive pediatric acute lymphoblastic leukemia, and its reversal by histone deacetylase inhibition.Effects of scaffold/matrix alteration on centromeric function and gene expression.FXN methylation predicts expression and clinical outcome in Friedreich ataxia.The evolutionary pattern of mutations in glioblastoma reveals therapy-mediated selection.Profiling DNA methylation differences between inbred mouse strains on the Illumina Human Infinium MethylationEPIC microarray.Restricted cell cycle is essential for clonal evolution and therapeutic resistance of pre-leukemic stem cellsEvidence of increased DNA methylation of the androgen receptor gene in occipital hair follicles from men with androgenetic alopeciaA case-sibling assessment of the association between skin pigmentation and other vitamin D-related factors and type 1 diabetes mellitusFrom reads to insight: a hitchhiker's guide to ATAC-seq data analysisA novel role for Lyl1 in primitive erythropoiesisThe changing landscape of research funding: challenges for mid-career researchers
P50
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P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Nick Wong
@ast
Nick Wong
@en
Nick Wong
@es
Nick Wong
@nl
type
label
Nick Wong
@ast
Nick Wong
@en
Nick Wong
@es
Nick Wong
@nl
prefLabel
Nick Wong
@ast
Nick Wong
@en
Nick Wong
@es
Nick Wong
@nl
P106
P1153
56527747700
7202836675
P31
P496
0000-0003-4393-7541