Structure-Activity Relationships of a Novel Group of Large-Conductance Ca2+-Activated K+(BK) Channel Modulators: The GoSlo-SR Family

Structure-Activity Relationships of a Novel Group of Large-Conductance Ca2+-Activated K+(BK) Channel Modulators: The GoSlo-SR Family

Item
http://www.wikidata.org/entity/Q56511930
Cerebrovascular dilation via selective targeting of the cholane steroid-recognition site in the BK channel β1-subunit by a novel nonsteroidal agentNS19504: a novel BK channel activator with relaxing effect on bladder smooth muscle spontaneous phasic contractions.Central role of the BK channel in urinary bladder smooth muscle physiology and pathophysiology.BK channel activators and their therapeutic perspectivesMolecular mechanisms underlying the effect of the novel BK channel opener GoSlo: involvement of the S4/S5 linker and the S6 segment.Effects of the novel BK (KCa 1.1) channel opener GoSlo-SR-5-130 are dependent on the presence of BKβ subunits.2014 Conway review lecture, Royal Academy of Medicine in Ireland: “S6, drugs and RCK and Bowl”.Molecular Determinants of BK Channel Functional Diversity and Functioning.Differential efficacy of GoSlo-SR compounds on BKα and BKαγ1-4 channels.Tagging of Endogenous BK Channels with a Fluorogen-Activating Peptide Reveals β4-Mediated Control of Channel Clustering in Cerebellum.Molecular structure and function of big calcium-activated potassium channels in skeletal muscle: pharmacological perspectives.Development of 1-Amino-4-(phenylamino)anthraquinone-2-sulfonate Sodium Derivatives as a New Class of Inhibitors of RANKL-Induced Osteoclastogenesis.Effect of a novel BKCa opener on BKCa currents and contractility of the rabbit corpus cavernosum.
P2860

Structure-Activity Relationships of a Novel Group of Large-Conductance Ca2+-Activated K+(BK) Channel Modulators: The GoSlo-SR Family

Item
http://www.wikidata.org/entity/Q56511930
description
im August 2012 veröffentlichter wissenschaftlicher Artikel
@de
scientific article published on 28 August 2012
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована в серпні 2012
@uk
name
Structure-Activity Relationships of a Novel Group of Large-Conductance Ca2+-Activated K+
@nl
Structure-Activity Relationshi ...... odulators: The GoSlo-SR Family
@en
type
label
Structure-Activity Relationships of a Novel Group of Large-Conductance Ca2+-Activated K+
@nl
Structure-Activity Relationshi ...... odulators: The GoSlo-SR Family
@en
prefLabel
Structure-Activity Relationships of a Novel Group of Large-Conductance Ca2+-Activated K+
@nl
Structure-Activity Relationshi ...... odulators: The GoSlo-SR Family
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P921
P356
P1433
P1476
Structure-activity relationshi ...... odulators: the GoSlo-SR family
@en
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P921