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In Vivo Chronic Stimulation Unveils Autoreactive Potential of Wiskott-Aldrich Syndrome Protein-Deficient B Cells.Revertant T lymphocytes in a patient with Wiskott-Aldrich syndrome: analysis of function and distribution in lymphoid organs.Lentiviral-mediated gene therapy leads to improvement of B-cell functionality in a murine model of Wiskott-Aldrich syndrome.Preclinical safety and efficacy of human CD34(+) cells transduced with lentiviral vector for the treatment of Wiskott-Aldrich syndrome.Lentiviral hematopoietic stem cell gene therapy in patients with Wiskott-Aldrich syndrome.B-cell development and functions and therapeutic options in adenosine deaminase-deficient patients.Intestinal microbiota sustains inflammation and autoimmunity induced by hypomorphic RAG defects.Dendritic cell functional improvement in a preclinical model of lentiviral-mediated gene therapy for Wiskott-Aldrich syndromeLentiviral-mediated gene therapy restores B cell tolerance in Wiskott-Aldrich syndrome patients.Wiskott-Aldrich syndrome protein-mediated actin dynamics control type-I interferon production in plasmacytoid dendritic cells.SOCS1 gene transfer accelerates the transition to heart failure through the inhibition of the gp130/JAK/STAT pathway.Wiskott-Aldrich syndrome protein deficiency in natural killer and dendritic cells affects antitumor immunity.Wiskott-Aldrich Syndrome protein deficiency perturbs the homeostasis of B-cell compartment in humans.IL-10 critically modulates B cell responsiveness in Rankl-/- mice.B-cell reconstitution after lentiviral vector-mediated gene therapy in patients with Wiskott-Aldrich syndrome.Platelets in Wiskott-Aldrich syndrome: victims or executioners?Preclinical modeling highlights the therapeutic potential of hematopoietic stem cell gene editing for correction of SCID-X1.Efficacy of lentiviral mediated gene therapy in an Omenn syndrome Rag2 mouse model is not hindered by inflammation and immune dysregulation.Insulin-like growth factor-1 protects from vascular stenosis and accelerates re-endothelialization in a rat model of carotid artery injury.Neutrophils drive type-I interferon production and autoantibodies in Wiskott-Aldrich syndrome.Autonomous role of Wiskott-Aldrich Syndrome platelet deficiency in inducing autoimmunity and inflammation.Lentiviral gene therapy corrects platelet phenotype and function in Wiskott-Aldrich patients
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description
hulumtuese
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Maria Carmina Castiello
@ast
Maria Carmina Castiello
@en
Maria Carmina Castiello
@es
Maria Carmina Castiello
@nl
type
label
Maria Carmina Castiello
@ast
Maria Carmina Castiello
@en
Maria Carmina Castiello
@es
Maria Carmina Castiello
@nl
prefLabel
Maria Carmina Castiello
@ast
Maria Carmina Castiello
@en
Maria Carmina Castiello
@es
Maria Carmina Castiello
@nl
P106
P1153
35809917800
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P31
P496
0000-0003-2581-9648