about
Spirocyclic β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors: from hit to lowering of cerebrospinal fluid (CSF) amyloid β in a higher speciesDiscovery of 7-tetrahydropyran-2-yl chromans: β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors that reduce amyloid β-protein (Aβ) in the central nervous systemSynthesis, characterization, and PK/PD studies of a series of spirocyclic pyranochromene BACE1 inhibitorsDiscovery of 5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine inhibitors of Erk28-Tetrahydropyran-2-yl chromans: highly selective beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitorsNon-charged thiamine analogs as inhibitors of enzyme transketolase.LAT1 activity of carboxylic acid bioisosteres: Evaluation of hydroxamic acids as substratesSynthesis, in vitro and in vivo activity of thiamine antagonist transketolase inhibitors.Reevaluating the Substrate Specificity of the L-Type Amino Acid Transporter (LAT1)l-Type amino acid transporter 1 activity of 1,2,3-triazolyl analogs of l-histidine and l-tryptophan
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Q27684297-4CAEF192-98FE-4208-91A8-E4217688F537Q27688093-11FADA44-70D5-4B6D-8277-CAE1F79D31F8Q27690124-1B26B7D0-C65B-4039-975F-54D4D62099BBQ27690178-6A9A7D47-72E6-456D-A7C1-52E2A61B9013Q27696198-59CFEFC4-054D-4ED4-914D-F38C2513D598Q40027274-7B571230-76A0-4033-B02D-274F0A1A913AQ42221833-6271B874-C9FE-427F-83D3-9EB77A9FF9B6Q46759205-09B09778-F5AF-4CEC-80FB-9FE043B4A974Q90494434-D80E4E30-7A98-4FF7-BCCD-1EBA45BD0E01Q93085665-B72D77AA-D0B0-4C84-A455-A125A084A624
P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Allen Thomas
@ast
Allen Thomas
@en
Allen Thomas
@es
Allen Thomas
@nl
type
label
Allen Thomas
@ast
Allen Thomas
@en
Allen Thomas
@es
Allen Thomas
@nl
prefLabel
Allen Thomas
@ast
Allen Thomas
@en
Allen Thomas
@es
Allen Thomas
@nl
P106
P31
P496
0000-0001-8313-0879