MLH1 Germline Epimutations as a Factor in Hereditary Nonpolyposis Colorectal Cancer
about
Comprehensive annotation of bidirectional promoters identifies co-regulation among breast and ovarian cancer genesBRCA1 promoter methylation in peripheral blood DNA of mutation negative familial breast cancer patients with a BRCA1 tumour phenotypeEpimutation and cancer: a new carcinogenic mechanism of Lynch syndrome (Review)Epigenetics of colorectal cancerMicrosatellite instability in colorectal cancerCarcinogenesis and microsatellite instability: the interrelationship between genetics and epigeneticsCpG methylation of a silent controlling element in the murine Avy allele is incomplete and unresponsive to methyl donor supplementation.Allele-specific CDH1 downregulation and hereditary diffuse gastric cancer.Constitutional methylation of the BRCA1 promoter is specifically associated with BRCA1 mutation-associated pathology in early-onset breast cancer.Correlation of global and gene-specific DNA methylation in maternal-infant pairs.Mismatch repair protein expression and colorectal cancer in Hispanics from Puerto RicoHereditary Non-Polyposis Colorectal Cancer: the rise and fall of a confusing term.Early onset MSI-H colon cancer with MLH1 promoter methylation, is there a genetic predisposition?Hereditary colon cancer: lynch syndromeApplication of molecular diagnostics for the detection of Lynch syndrome.Transgenerational epigenetic inheritance: more questions than answers.Clinical problems of colorectal cancer and endometrial cancer cases with unknown cause of tumor mismatch repair deficiency (suspected Lynch syndrome)Heritable germline epimutation of MSH2 in a family with hereditary nonpolyposis colorectal cancer.Epigenetics and phenotypic variation in mammals.Causes and consequences of microsatellite instability in gastric carcinogenesis.Intra- and interindividual epigenetic variation in human germ cells.Frequency of deletions of EPCAM (TACSTD1) in MSH2-associated Lynch syndrome cases.A review on the molecular diagnostics of Lynch syndrome: a central role for the pathology laboratory.Non-random, individual-specific methylation profiles are present at the sixth CTCF binding site in the human H19/IGF2 imprinting control regionAnticipation in lynch syndrome: where we are where we goGermline promoter hypermethylation of tumor suppressor genes in gastric cancerEpigenetic memory in mammals.Colorectal cancer: a model for epigenetic tumorigenesis.Male reproductive health and prostate cancer riskLeukocyte DNA methylation and colorectal cancer among male smokers.Dietary factors, genetic and epigenetic influences in colorectal cancer.MLH1 methylation screening is effective in identifying epimutation carriersAberrant promoter hypermethylation and genomic hypomethylation in tumor, adjacent normal tissues and blood from breast cancer patients.Patients with an unexplained microsatellite instable tumour have a low risk of familial cancerThe role of MYH and microsatellite instability in the development of sporadic colorectal cancer.Germline epigenetic regulation of KILLIN in Cowden and Cowden-like syndrome.Features of trinucleotide repeat instability in vivo.De novo constitutional MLH1 epimutations confer early-onset colorectal cancer in two new sporadic Lynch syndrome cases, with derivation of the epimutation on the paternal allele in oneAbsence of germline mono-allelic promoter hypermethylation of the CDH1 gene in gastric cancer patients.Germline epimutation in humans.
P2860
Q21145667-0A96994E-39A2-4F66-9A81-648D3CAE080EQ21195223-A6A377CA-E63E-439D-ABFE-E1C8C9FB374AQ22255392-D965AD8A-4D6C-4629-8E48-DCBDC51C61E8Q24598045-71D94471-85BC-453B-BECE-39550FC67514Q24627393-2A8F38D0-BF9F-4A71-96FF-2F90D5365FD9Q28253670-9A608215-1B1B-407F-97D7-B7344273CC2EQ33530122-F1882974-EE60-4705-BBEE-4C28A412E54FQ33630653-8C9ADE2E-381E-4997-835C-781E007D6B39Q33646285-CEB433E3-C2EE-4E86-906D-B5DD88AE45F6Q33741841-CA404AB7-3607-4E02-B8B9-C7DB32D99973Q33862772-6FB09C64-7ADD-434C-85FE-A49B61E2B8A2Q33866105-A3A109D2-78D8-48A2-BE2E-9600C884D302Q33892398-95D378B7-A39E-426B-A628-9AE7D490BFBDQ33918280-56A0095B-AF69-4577-8466-F86BB974497AQ34088809-D8FAC50F-DDA1-434E-822F-DB72BB41DEDDQ34341597-12BCDDD2-ADBE-45AE-B413-BC924A3B9E65Q34351784-44F47295-1760-428F-B22E-7EA8F3892C3CQ34563305-E03E4D58-724D-42ED-916C-75ED8E4B6321Q34567418-1E4B31A9-B29D-48E1-A1F4-CCD868758FAFQ34589660-CCBA3297-0255-4E65-A44F-40E6584914B3Q34658413-C43E1997-9F95-46AA-B916-F7E0AC29D8DEQ34756357-49E64A7A-A1B6-4EEE-B0FA-1C6909678965Q35013990-02D13596-85CB-4B7B-80A5-EFE6E94FC738Q35130565-DE04DAFA-B49C-4B18-902E-EC39993B10A2Q35560811-FF9477F3-9166-425F-B218-F2806E525C55Q35653610-42C718B5-0E92-4DC6-9A21-02AD891CD08BQ35711156-42F4FC38-4028-4DF0-BD96-40331EF0D19AQ35761237-70003FE1-A934-4A9F-8F59-E4E877EEF585Q35875365-15FB158D-63C0-44C5-9480-150222D53DD6Q36177097-1F3205C5-F064-41BF-A8D7-0F49C7B7C5E4Q36244244-D1CC819F-A671-4981-B22D-2D90B6B6B281Q36403949-3F97C5F3-3FCE-499C-A173-CA4323C17AE9Q36600205-AE4D9109-F482-4C5E-8861-CB030C46C155Q36609603-E1CBA500-4CA4-4250-9D19-7E73E6C45F4DQ36611848-C5804420-4E75-4BF4-8C90-BF7F66560624Q36847856-83E712BF-0954-4DE3-B1FA-BBEC458C75B6Q37048169-E915756F-ECEC-4480-A7AB-052A63B4CC49Q37224356-FE2B6085-9C76-48FD-BC00-02B4EC54895CQ37318009-8F719F24-A80F-4633-9ABA-A3F74E245CE0Q37346208-B2E14771-15BD-491A-B76C-01E113F1B2C1
P2860
MLH1 Germline Epimutations as a Factor in Hereditary Nonpolyposis Colorectal Cancer
description
article
@en
im November 2005 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована в листопаді 2005
@uk
ലേഖനം
@ml
name
MLH1 Germline Epimutations as a Factor in Hereditary Nonpolyposis Colorectal Cancer
@en
MLH1 Germline Epimutations as a Factor in Hereditary Nonpolyposis Colorectal Cancer
@nl
type
label
MLH1 Germline Epimutations as a Factor in Hereditary Nonpolyposis Colorectal Cancer
@en
MLH1 Germline Epimutations as a Factor in Hereditary Nonpolyposis Colorectal Cancer
@nl
prefLabel
MLH1 Germline Epimutations as a Factor in Hereditary Nonpolyposis Colorectal Cancer
@en
MLH1 Germline Epimutations as a Factor in Hereditary Nonpolyposis Colorectal Cancer
@nl
P2093
P50
P1433
P1476
MLH1 Germline Epimutations as a Factor in Hereditary Nonpolyposis Colorectal Cancer
@en
P2093
Allan Spigelman
Andrew Buckle
Catherine Suter
David Martin
Deborah Packham
Graeme Suthers
Jack Goldblatt
Kayfong Cheong
Megan Hitchins
P304
P356
10.1053/J.GASTRO.2005.09.003
P407
P577
2005-11-01T00:00:00Z