about
Aminothiazoles as Potent and Selective Sirt2 Inhibitors: A Structure-Activity Relationship StudyStructure-Based Development of an Affinity Probe for Sirtuin 2Chemically Induced Degradation of Sirtuin 2 (Sirt2) by a Proteolysis Targeting Chimera (PROTAC) Based on Sirtuin Rearranging Ligands (SirReals).Selective Sirt2 inhibition by ligand-induced rearrangement of the active site.The Current State of NAD(+) -Dependent Histone Deacetylases (Sirtuins) as Novel Therapeutic Targets.Fluorescence-based screening assays for the NAD⁺-dependent histone deacetylase smSirt2 from Schistosoma mansoni.Synthesis and biological evaluation of 8-hydroxy-2,7-naphthyridin-2-ium salts as novel inhibitors of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE)Chromo-pharmacophores: photochromic diarylmaleimide inhibitors for sirtuinsBET bromodomain ligands: Probing the WPF shelf to improve BRD4 bromodomain affinity and metabolic stability[HIV-1 eradication with the "shock and kill" strategy]A Continuous, Fluorogenic Sirtuin 2 Deacylase Assay: Substrate Screening and Inhibitor EvaluationSmall molecules as tools to study the chemical epigenetics of lysine acetylationChemical Epigenetics: The Impact of Chemical and Chemical Biology Techniques on Bromodomain Target ValidationValidation of the Slow Off-Kinetics of Sirtuin-Rearranging Ligands (SirReals) by Means of Label-Free Electrically Switchable Nanolever Technology
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description
researcher
@en
ricercatore
@it
wetenschapper
@nl
հետազոտող
@hy
name
Matthias Schiedel
@ast
Matthias Schiedel
@en
Matthias Schiedel
@es
Matthias Schiedel
@nl
type
label
Matthias Schiedel
@ast
Matthias Schiedel
@en
Matthias Schiedel
@es
Matthias Schiedel
@nl
prefLabel
Matthias Schiedel
@ast
Matthias Schiedel
@en
Matthias Schiedel
@es
Matthias Schiedel
@nl
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