about
The human DnaJ homologue (Hdj)-1/heat-shock protein (Hsp) 40 co-chaperone is required for the in vivo stabilization of the cystic fibrosis transmembrane conductance regulator by Hsp70[(Cp-R)M(CO)3] (M=Re or 99mTc) Arylsulfonamide, arylsulfamide, and arylsulfamate conjugates for selective targeting of human carbonic anhydrase IXS-nitrosoglutathione increases cystic fibrosis transmembrane regulator maturation.A comparison of 14 antibodies for the biochemical detection of the cystic fibrosis transmembrane conductance regulator protein.Evaluation of Acridine Orange Derivatives as DNA-Targeted Radiopharmaceuticals for Auger Therapy: Influence of the Radionuclide and Distance to DNAImmunohistochemistry of CFTR in native tissues and primary epithelial cell cultures.Assessment of CFTR localisation in native airway epithelial cells obtained by nasal brushing.Antibodies for CFTR studies.Biophysical characterization and antineoplastic activity of new bis(thiosemicarbazonato) Cu(II) complexes.Prolonged treatment of cells with genistein modulates the expression and function of the cystic fibrosis transmembrane conductance regulator.Anthracene-terpyridine metal complexes as new G-quadruplex DNA binders.Re(I) and Tc(I) complexes for targeting nitric oxide synthase: influence of the chelator in the affinity for the enzyme.Design and biological evaluation of new platinum(II) complexes bearing ligands with DNA-targeting ability.Novel heterobimetallic radiotheranostic: preparation, activity, and biodistribution.Copper(II) Complexes of Phenanthroline and Histidine Containing Ligands: Synthesis, Characterization and Evaluation of their DNA Cleavage and Cytotoxic Activity.Mono- and dicationic Re(I)/(99m)Tc(I) tricarbonyl complexes for the targeting of energized mitochondria.Synthesis and biological studies of pyrazolyl-diamine Pt(II) complexes containing polyaromatic DNA-binding groups.[RuII(η⁵-C₅H₅)(bipy)(PPh₃)]⁺, a promising large spectrum antitumor agent: cytotoxic activity and interaction with human serum albumin.99mTc(I)/Re(I) tricarbonyl complexes for in vivo targeting of melanotic melanoma: Synthesis and biological evaluation.Cytotoxic gold compounds: synthesis, biological characterization and investigation of their inhibition properties of the zinc finger protein PARP-1.Radiohalogenated 4-anilinoquinazoline-based EGFR-TK inhibitors as potential cancer imaging agents.Pt(II) complexes with bidentate and tridentate pyrazolyl-containing chelators: synthesis, structural characterization and biological studies.Copper(II) complexes with tridentate pyrazole-based ligands: synthesis, characterization, DNA cleavage activity and cytotoxicity.Metal-based inhibition of poly(ADP-ribose) polymerase--the guardian angel of DNA.Re and Tc tricarbonyl complexes: from the suppression of NO biosynthesis in macrophages to in vivo targeting of inducible nitric oxide synthase.Tricarbonyl M(I) (M = Re, (99m)Tc) complexes bearing acridine fluorophores: synthesis, characterization, DNA interaction studies and nuclear targeting.Establishment and characterization of a novel polarized MDCK epithelial cellular model for CFTR studies.Unusually common cystic fibrosis mutation in Portugal encodes a misprocessed protein.BAG-1 stabilizes mutant F508del-CFTR in a ubiquitin-like-domain-dependent manner.Enhanced Cytotoxicity and Reactivity of a Novel Platinum(IV) Family with DNA-Targeting Naphthalimide Ligands.A Multifunctional Radiotheranostic Agent for Dual Targeting of Breast Cancer Cells.Combining imaging and anticancer properties with new heterobimetallic Pt(ii)/M(i) (M = Re, 99mTc) complexes.Technetium-99m complexes of l-arginine derivatives for targeting amino acid transporters.Evaluation of cellular uptake, cytotoxicity and cellular ultrastructural effects of heteroleptic oxidovanadium(IV) complexes of salicylaldimines and polypyridyl ligands.Study of the synthesis, antiproliferative properties, and interaction with DNA and polynucleotides of cisplatin-like Pt(II) complexes containing carcinogenic polyaromatic amines.Impact of the cystic fibrosis mutation F508del-CFTR on renal cyst formation and growthApplication of microwave-assisted heating to the synthesis of Pt(II) complexesNew ternary bipyridine–terpyridine copper(ii) complexes as self-activating chemical nucleasesAnticancer activity of structurally related ruthenium(II) cyclopentadienyl complexesIsostructural Re(i)/99mTc(i) tricarbonyl complexes for cancer theranostics
P50
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P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Filipa Mendes
@ast
Filipa Mendes
@en
Filipa Mendes
@es
Filipa Mendes
@nl
type
label
Filipa Mendes
@ast
Filipa Mendes
@en
Filipa Mendes
@es
Filipa Mendes
@nl
prefLabel
Filipa Mendes
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Filipa Mendes
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Filipa Mendes
@es
Filipa Mendes
@nl
P106
P1153
36465350400
P31
P496
0000-0003-0646-1687