about
Structural and functional analysis of the anti-malarial drug target prolyl-tRNA synthetaseStructure of Prolyl-tRNA Synthetase-Halofuginone Complex Provides Basis for Development of Drugs against Malaria and ToxoplasmosisMitochondria are the target organelle of differentiation-inducing factor-3, an anti-tumor agent isolated from Dictyostelium discoideum [corrected]Peltophorum africanum, a traditional South African medicinal plant, contains an anti HIV-1 constituent, betulinic acid.Evidence that differentiation-inducing factor-1 controls chemotaxis and cell differentiation, at least in part, via mitochondria in D. discoideum.Antimicrobial and antioxidant properties of methanol extract, fractions and compounds from the stem bark of Entada abyssinica Stend ex A. SatabieZFC3H1, a zinc finger protein, modulates IL-8 transcription by binding with celastramycin A, a potential immune suppressor.Development of novel DIF-1 derivatives that selectively suppress innate immune responses.Weight loss by Ppc-1, a novel small molecule mitochondrial uncoupler derived from slime moldDevelopment of a Terpenoid Alkaloid-like Compound Library Based on the Humulene Skeleton.Halofuginone enhances the chemo-sensitivity of cancer cells by suppressing NRF2 accumulation.Properties of a non-bioactive fluorescent derivative of differentiation-inducing factor-3, an anti-tumor agent found in Dictyostelium discoideum.Agarol, an ergosterol derivative from Agaricus blazei, induces caspase-independent apoptosis in human cancer cells.Derivatives of Dictyostelium differentiation-inducing factors inhibit lysophosphatidic acid-stimulated migration of murine osteosarcoma LM8 cells.Derivatives of Dictyostelium discoideum differentiation-inducing factor-3 suppress the activities of Trypanosoma cruzi in vitro and in vivo.A phytoceramide analog stimulates the production of chemokines through CREB activation in human endothelial cells.5,19-cyclo-9beta,10xi-androstane-3,17-dione promotes neurotrophic factor biosynthesis in 1321N1 human astrocytoma cells and improves passive avoidance learning impairment.Induction of Osteopontin by Dengue Virus-3 Infection in THP-1 Cells: Inhibition of the Synthesis by Brefelamide and Its Derivative.Targeting Prolyl-tRNA Synthetase to Accelerate Drug Discovery against Malaria, Leishmaniasis, Toxoplasmosis, Cryptosporidiosis, and Coccidiosis.Exploration of a new type of antimalarial compounds based on febrifugine.Identification of brefelamide as a novel inhibitor of osteopontin that suppresses invasion of A549 lung cancer cells.Defects in the synthetic pathway prevent DIF-1 mediated stalk lineage specification cascade in the non-differentiating social amoeba, Acytostelium subglobosum.Potent antimalarial febrifugine analogues against the plasmodium malaria parasite.Isolation of a Cyclic Depsipetide, Aspergillicin F, and Synthesis of Aspergillicins with Innate Immune-Modulating Activity.Glutathione S-transferase 4 is a putative DIF-binding protein that regulates the size of fruiting bodies in Dictyostelium discoideum.Oral administration of Dictyostelium differentiation-inducing factor 1 lowers blood glucose levels in streptozotocin-induced diabetic rats.Apoptotic effects of satratoxin H is mediated through DNA double-stranded break in PC12 cells.Correction: ZFC3H1, a Zinc Finger Protein, Modulates IL-8 Transcription by Binding with Celastramycin A, a Potential Immune Suppressor.Biological activities of novel derivatives of DIF-1 isolated from Dictyostelium.Exploitation of the derivatives of Dictyostelium differentiation-inducing factor-1, which promote glucose consumption in mammalian cells.Regulation of IL-2 production in Jurkat cells by Dictyostelium-derived factors.Inhibitory effect of hericenone B from Hericium erinaceus on collagen-induced platelet aggregation.Antimycobacterial flavonoids from the leaf extract of Galenia africana.Autophagic or necrotic cell death triggered by distinct motifs of the differentiation factor DIF-1.Novel spirocyclic trichothecanes, spirotenuipesine A and B, isolated from entomopathogenic fungus, Paecilomyces tenuipes.The Dictyostelium prestalk inducer DIF-1 directs phosphorylation of a bZIP transcription factor.Metarhizin A suppresses cell proliferation by inhibiting cytochrome c oxidase activity.Isolation, Synthesis, and Biological Activity of Chlorinated Alkylresorcinols from Dictyostelium Cellular Slime Molds.Prenylated quinolinecarboxylic acid derivative suppresses immune response through inhibition of PAK2.Effect of brefelamide on proliferation of 1321N1 human astrocytoma cells induced by glial cell line-derived neurotrophic factor.
P50
Q27694602-A91E4700-951A-40A1-9361-7C1535F3C91CQ27700051-CC0E4B5E-EBD4-45F4-9FA2-70026114923DQ28535373-8ECF1FD0-0465-4171-96B9-0AF0B335E313Q33408520-06CFB5F8-1E1E-4E00-9885-A05BBC8B37C3Q33830524-7C207FBF-716F-48BE-9933-86A9809A450CQ33965469-23DFE8E2-6FAA-4CA3-BF6A-2DF867EE8738Q34441044-226B81E2-6459-4D79-8295-16F247364318Q34482837-47B95087-3AAA-4E10-BD10-25F72C1EEA20Q35069125-57E8D813-5F1A-456E-A3C5-4FDCE2CD9C12Q36131875-D52EA765-8A82-404C-92F1-E46912D5919FQ36236732-76775E35-9E79-4463-987F-B2B3BAA465C6Q38785788-FDE99016-EBAD-4393-97CD-77EE9CD4821EQ38792810-FD7A6DAE-A776-4F96-B13E-16E4920C6368Q38865906-5BC10D0D-6378-4B91-B24F-EE08DAFB1154Q39178391-B3F219D2-5AEA-4B8F-A254-0EC2370CFA69Q39535830-F6CE2857-24C6-41DA-94A0-CF1A36046BB1Q40057418-F3244DE4-334B-4550-A1EC-07EB5E3B85DAQ40061235-B94A319D-8320-494A-B41A-80E765589B92Q40068818-975E0E1F-E34A-4B67-B6A5-003C098D8B27Q40253681-06161251-3DC8-4FCF-A627-F91ADBE9F5ADQ40585458-E9C7628B-3CA8-49F2-9C22-E78F1912AF02Q40723016-A284B2FD-129D-438A-A7E4-86C4E32D3264Q40728859-C5341249-3A6C-484B-804B-88A7188E8B31Q41052093-7694B9B5-CC8D-43C1-8E4C-C8FAF1D1DD56Q41682637-83CC59C3-B99B-4FE7-B49D-5DC9D142D563Q42492583-840CE914-2E14-4D9E-BD66-DC2B8270CCE5Q42716655-BF295326-AA44-4A9A-941E-986F67C2DED0Q42760115-E653150E-57AD-43B1-A029-FC58C073C8BFQ42806988-53ACFB7D-BC9B-48F5-9BA6-AB59C5B8F400Q42808160-3FAE26A2-A763-4B08-AEA2-5602F1609835Q42835283-78BA77E9-A4BF-4BF8-967F-CE09E466DDB5Q42967797-470F8825-1EBE-4E71-8AA3-66DC7B16B94DQ43207488-6D53C5FA-5278-4BE2-9300-69304E8A3CDCQ43449702-D1801BC5-C5D9-477B-85C2-B20FDCAC7D63Q44729562-0BC6C133-4238-4DD5-939C-EB5E3B6F5473Q46236206-1D6A9B0B-0D02-4BC7-80E9-0D0096A555A9Q46910220-FD023659-69F8-4BBF-AD47-F3D023D19AD3Q47785810-A797F30E-86CB-4C66-8AC0-9B96F207FB27Q47885916-A3F15A6E-AB60-49CE-BB25-0C3020F32D6CQ50018186-90F54636-1DD8-4B30-938E-6CFB71D63940
P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Haruhisa Kikuchi
@ast
Haruhisa Kikuchi
@en
Haruhisa Kikuchi
@es
Haruhisa Kikuchi
@nl
type
label
Haruhisa Kikuchi
@ast
Haruhisa Kikuchi
@en
Haruhisa Kikuchi
@es
Haruhisa Kikuchi
@nl
prefLabel
Haruhisa Kikuchi
@ast
Haruhisa Kikuchi
@en
Haruhisa Kikuchi
@es
Haruhisa Kikuchi
@nl
P106
P1153
7402241938
P31
P496
0000-0001-6938-0185