about
Mapping replication dynamics in Trypanosoma brucei reveals a link with telomere transcription and antigenic variation.Does DNA replication direct locus-specific recombination during host immune evasion by antigenic variation in the African trypanosome?Genome-wide and protein kinase-focused RNAi screens reveal conserved and novel damage response pathways in Trypanosoma brucei.RNAi screening identifies Trypanosoma brucei stress response protein kinases required for survival in the mouse.The protozoan nucleus.Genome-wide mapping reveals conserved and diverged R-loop activities in the unusual genetic landscape of the African trypanosome genomeConditional genome engineering reveals canonical and divergent roles for the Hus1 component of the 9-1-1 complex in the maintenance of the plastic genome of LeishmaniaThe ATR kinase of Trypanosoma brucei links DNA damage signalling and monoallelic control of surface antigen gene expression during antigenic variationRibonucleaseH1-targeted R-loops in surface antigen gene expression sites can direct trypanosome immune evasionGenome-wide mapping reveals conserved and diverged R-loop activities in the unusual genetic landscape of the African trypanosome genomeEvaluation of mechanisms that may generate DNA lesions triggering antigenic variation in African trypanosomesRibonuclease H1-targeted R-loops in surface antigen gene expression sites can direct trypanosome immune evasionApplication of long read sequencing to determine expressed antigen diversity in Trypanosoma brucei infectionsTranscription activity contributes to the firing of non-constitutive origins in African trypanosomes helping to maintain robustness in S-phase durationTrypanosoma brucei ribonuclease H2A is an essential R-loop processing enzyme whose loss causes DNA damage during transcription initiation and antigenic variation
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description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Richard McCulloch
@ast
Richard McCulloch
@en
Richard McCulloch
@es
Richard McCulloch
@nl
type
label
Richard McCulloch
@ast
Richard McCulloch
@en
Richard McCulloch
@es
Richard McCulloch
@nl
prefLabel
Richard McCulloch
@ast
Richard McCulloch
@en
Richard McCulloch
@es
Richard McCulloch
@nl
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P106
P31
P496
0000-0001-5739-976X