CoMFA/CoMSIA 3D-QSAR of pyrimidine inhibitors of Pneumocystis carinii dihydrofolate reductase

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CoMFA/CoMSIA 3D-QSAR of pyrimidine inhibitors of Pneumocystis carinii dihydrofolate reductase

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im April 2012 veröffentlichter wissenschaftlicher Artikel

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wetenschappelijk artikel

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наукова стаття, опублікована у квітні 2012

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CoMFA/CoMSIA 3D-QSAR of pyrimi ...... arinii dihydrofolate reductase

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CoMFA/CoMSIA 3D-QSAR of pyrimi ...... arinii dihydrofolate reductase

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CoMFA/CoMSIA 3D-QSAR of pyrimi ...... arinii dihydrofolate reductase

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CoMFA/CoMSIA 3D-QSAR of pyrimi ...... arinii dihydrofolate reductase

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CoMFA/CoMSIA 3D-QSAR of pyrimi ...... arinii dihydrofolate reductase

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CoMFA/CoMSIA 3D-QSAR of pyrimi ...... arinii dihydrofolate reductase

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P1476

CoMFA/CoMSIA 3D-QSAR of pyrimi ...... arinii dihydrofolate reductase

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P2093

Delphine Forge

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Guilherme B. L. de Freitas

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Jocley Q. Araújo

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Magaly G. Albuquerque

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Osvaldo A. Santos-Filho

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Ricardo B. de Alencastro

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Thiago O. Marinho

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P2860

Analysis of quinazoline and pyrido[2,3-d]pyrimidine N9-C10 reversed-bridge antifolates in complex with NADP+ and Pneumocystis carinii dihydrofolate reductase

Structural analysis ofPneumocystis cariniiand human DHFR complexes with NADPH and a series of five potent 6-[5′-(ω-carboxyalkoxy)benzyl]pyrido[2,3-d]pyrimidine derivatives

Structure-based design and synthesis of lipophilic 2,4-diamino-6-substituted quinazolines and their evaluation as inhibitors of dihydrofolate reductases and potential antitumor agents

VMD: visual molecular dynamics

Iterative partial equalization of orbital electronegativity—a rapid access to atomic charges

The neuropathogenesis of AIDS

Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase inhibitors and antitumor agents: synthesis and biological activities of 2,4-diamino-5-methyl-6-[(monosubstituted anilino)methyl] pyrido[2,3-d]pyrimidines

Evaluation of potent inhibitors of dihydrofolate reductase in a culture model for growth of Pneumocystis carinii

Dihydropteroate synthase gene mutations in Pneumocystis and sulfa resistance.

Prevention of infection due to Pneumocystis spp. in human immunodeficiency virus-negative immunocompromised patients.

P2888

s00894-012-1399-y

P304

4061-4072

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P31

scholarly article

P356

10.1007/S00894-012-1399-Y

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P433

http://www.w3.org/2001/XMLSchema#string

P478

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P50

Nubia Boechat

Lucas Villas Bôas Hoelz

P577

2012-04-14T00:00:00Z

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P698

22527273

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