about
Antiviral activity of benzimidazole derivatives. II. Antiviral activity of 2-phenylbenzimidazole derivatives.Efficacy of novel acridine derivatives in the inhibition of hPrP90-231 prion protein fragment toxicity.Novel biguanide-based derivatives scouted as TAAR1 agonists: Synthesis, biological evaluation, ADME prediction and molecular docking studies.New insights into the structure of the trace amine-associated receptor 2: Homology modelling studies exploring the binding mode of 3-iodothyronamine.Antiviral activity of benzimidazole derivatives. III. Novel anti-CVB-5, anti-RSV and anti-Sb-1 agents.Exhaustive CoMFA and CoMSIA analyses around different chemical entities: a ligand-based study exploring the affinity and selectivity profiles of 5-HT1A ligands.Targeting species-specific trace amine-associated receptor 1 ligands: to date perspective of the rational drug design process.Benzimidazole-based derivatives as privileged scaffold developed for the treatment of the RSV infection: a computational study exploring the potency and cytotoxicity profiles.Fight Against H1N1 Influenza A Virus: Recent Insights Towards the Development of Druggable Compounds.Novel celecoxib analogues inhibit glial production of prostaglandin E2, nitric oxide, and oxygen radicals reverting the neuroinflammatory responses induced by misfolded prion protein fragment 90-231 or lipopolysaccharide.Antiviral activity of benzotriazole derivatives. 5-[4-(Benzotriazol-2-yl)phenoxy]-2,2-dimethylpentanoic acids potently and selectively inhibit Coxsackie Virus B5.Clofazimine analogs with antileishmanial and antiplasmodial activity.Antitubercular activity of quinolizidinyl/pyrrolizidinylalkyliminophenazines.Acridine derivatives as anti-BVDV agents.Synergistic experimental/computational studies on arylazoenamine derivatives that target the bovine viral diarrhea virus RNA-dependent RNA polymerase.Antiviral and cytotoxic activities of aminoarylazo compounds and aryltriazene derivatives.Host dihydrofolate reductase (DHFR)-directed cycloguanil analogues endowed with activity against influenza virus and respiratory syncytial virus.Antiviral activity of benzimidazole derivatives. I. Antiviral activity of 1-substituted-2-[(benzotriazol-1/2-yl)methyl]benzimidazoles.Synthesis and Antiplasmodial Activity of Novel Chloroquine Analogues with Bulky Basic Side Chains.3-(4-Chloro-phenyl-diazen-yl)-1-methyl-1,4,5,6-tetra-hydro-pyridine.Pharmacophore modeling, resistant mutant isolation, docking, and MM-PBSA analysis: Combined experimental/computer-assisted approaches to identify new inhibitors of the bovine viral diarrhea virus (BVDV).Novel quinolizidinyl derivatives as antiarrhythmic agents: 2. Further investigation.Antimicrobial and cytotoxic arylazoenamines. Part III: antiviral activity of selected classes of arylazoenamines.Benzimidazole derivatives endowed with potent antileishmanial activity.Quinolizidinyl-benzimidazoles as platelet-antiaggregating agents.9-Aminoacridine-based agents impair the bovine viral diarrhea virus (BVDV) replication targeting the RNA-dependent RNA polymerase (RdRp).Multitarget Therapeutic Leads for Alzheimer's Disease: Quinolizidinyl Derivatives of Bi- and Tricyclic Systems as Dual Inhibitors of Cholinesterases and β-Amyloid (Aβ) Aggregation.Rational design, chemical synthesis and biological evaluation of novel biguanides exploring species-specificity responsiveness of TAAR1 agonists.New arylsparteine derivatives as positive inotropic drugs.Quinolizidinyl derivatives of bi- and tricyclic systems as potent inhibitors of acetyl- and butyrylcholinesterase with potential in Alzheimer’s diseaseInhibition of Chloride Intracellular Channel 1 (CLIC1) as Biguanide Class-Effect to Impair Human Glioblastoma Stem Cell ViabilitySynthesis, biological evaluation and molecular modeling of novel azaspiro dihydrotriazines as influenza virus inhibitors targeting the host factor dihydrofolate reductase (DHFR)A homology modelling-driven study leading to the discovery of the first mouse trace amine-associated receptor 5 (TAAR5) antagonistsCelecoxib Inhibits Prion Protein 90-231-Mediated Pro-inflammatory Responses in Microglial CellsPyrazole and imidazo[1,2-b]pyrazole Derivatives as New Potential Antituberculosis AgentsSynthesis and Biological Evaluation of Novel (thio)semicarbazone-Based Benzimidazoles as Antiviral Agents against Human Respiratory VirusesExploring the effectiveness of novel benzimidazoles as CB2 ligands: synthesis, biological evaluation, molecular docking studies and ADMET predictionTrace amine associated receptor 1 (TAAR1) modulators: a patent review (2010-present)
P50
Q33548588-8C2A3285-3696-4218-8E52-BB078E657128Q33560026-561BC91C-72EC-4E34-BA07-5347230071F9Q34544308-8A001126-6FFF-4C37-BE4A-8D5080412EA5Q34545052-6003371C-480C-4275-85E9-4BF6E9F64BCDQ35216917-91584986-4FF7-46E0-8745-DB96CB28DAD9Q36257797-5F539F4E-751E-4425-8F6B-67AB7C0D67FCQ38644990-D846F56F-ADE6-45D9-BFA0-07C712AA2527Q38713020-061ABDDD-A89E-4B1F-AA06-09B813819FABQ38727683-38093217-A490-4242-8CC0-C289A56ABE5BQ38739954-41F41931-8EE9-4AB9-8862-311D60020A68Q38829850-0B613CF0-4C67-4E71-8557-F5F5AF82FF46Q38929733-E6F9B951-15CF-4AB2-B8B5-95BCAC993B4FQ38933116-DE8360A9-A8C5-46D1-9266-EAEE732A4176Q39534847-4E7435FA-8ACC-4750-A595-F1C3ED6E8DF1Q39678894-A3882539-E131-46B3-884F-077F98784751Q39844924-8D6C4437-BFFB-4A5F-9650-DC01C1CFDAD9Q40212795-11CCA518-1EF2-43E3-A84B-D87617D1E4C0Q40403897-B49F58A1-FCC1-411A-8CCD-13E5B86CC1AEQ41917145-8DAD09CE-0987-454C-87B2-D9BDFF2C94F4Q42402405-6FEC7843-C8E1-4514-9DB5-69BD7AECD336Q42995065-7B22E924-EC9E-4728-A835-F07E4B8DBF7CQ43051519-D0BD5751-8543-4FEA-B4A3-F72AE4DC9AA7Q45130619-A339CAD2-A466-40F9-8A8D-08ACFF09F473Q46242806-8A48A3EC-06DE-48F8-ACE5-4232F2B6B922Q46584281-E520143F-4AC3-4CD2-B359-31764ABC2A32Q47554946-E1F343B9-754B-4C43-9C84-9764DE29D773Q48202416-3A2ABB69-4A8D-4100-8B27-89C7C8BE0D7BQ48510809-166FD33C-2B08-4CE0-8381-76F995A691F1Q53540568-BA720BC7-DB51-405E-9571-00DC0E8105A4Q56986585-B91F98B4-7A6A-4611-9992-8839768D79D2Q58728819-0FDE555C-0E2B-47F4-A5F1-0344D2FA4A0CQ59359425-AE5EA93A-030A-4271-A603-4865EA41E8C6Q62590310-550E0425-0DC9-4462-A4A4-B31561E30920Q86004050-1559CBAF-3F31-444A-8519-D1CEBF72AA8BQ88786679-3AEEC7E3-A0B3-4E8C-A5BC-55745A3977F2Q90694546-7B668B4B-2FC6-4428-A134-29A10AB44A88Q91065180-AF225D06-BA3E-48B6-BAE9-5F619C9206FBQ92181514-8391A149-D3BA-48DE-9F34-6035EBDBFCD6
P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Michele Tonelli
@ast
Michele Tonelli
@en
Michele Tonelli
@es
Michele Tonelli
@nl
type
label
Michele Tonelli
@ast
Michele Tonelli
@en
Michele Tonelli
@es
Michele Tonelli
@nl
prefLabel
Michele Tonelli
@ast
Michele Tonelli
@en
Michele Tonelli
@es
Michele Tonelli
@nl
P106
P1153
24578243300
P31
P496
0000-0003-1518-2890