about
Down-regulation of multiple cytochrome P450 gene products by inflammatory mediators in vivo. Independence from the hypothalamo-pituitary axisNitric oxide-dependent CYP2B degradation is potentiated by a cytokine-regulated pathway and utilizes the immunoproteasome subunit LMP2Characterization of CYP4A induction in rat liver by inflammatory stimuli: dependence on sex, strain, and inflammation-evoked hypophagia.Modulation of drug metabolism in infectious and inflammatory diseases.Altered inflammatory responses to Citrobacter rodentium infection, but not bacterial lipopolysaccharide, in mice lacking the Cyp4a10 or Cyp4a14 genes.Regulation of cytochrome P450 expression by sphingolipids.Hepatic and renal cytochrome p450 gene regulation during citrobacter rodentium infection in wild-type and toll-like receptor 4 mutant mice.Expression of UDP-glucuronosyltransferase isoform mRNAs during inflammation and infection in mouse liver and kidneyMechanisms of cytochrome P450 regulation by inflammatory mediators.Impact of infectious and inflammatory disease on cytochrome P450-mediated drug metabolism and pharmacokineticsTranscriptional suppression of cytochrome P450 genes by endogenous and exogenous chemicals.Inhibition of estrogen-induced mammary tumor formation in MMTV-aromatase transgenic mice by 4-chlorophenylacetate.The receptor tyrosine kinase EphB2 promotes hepatic fibrosis in mice.Gene-specific effects of inflammatory cytokines on cytochrome P450 2C, 2B6 and 3A4 mRNA levels in human hepatocytes.Nitric oxide-dependent proteasomal degradation of cytochrome P450 2B proteinsMetabolomics reveals that hepatic stearoyl-CoA desaturase 1 downregulation exacerbates inflammation and acute colitisRoles of nitric oxide in inflammatory downregulation of human cytochromes P450.Hepatic flavin-containing monooxygenase gene regulation in different mouse inflammation models.Dual mechanisms of CYP3A protein regulation by proinflammatory cytokine stimulation in primary hepatocyte cultures.Nitric oxide and interleukin-1β stimulate the proteasome-independent degradation of the retinoic acid hydroxylase CYP2C22 in primary rat hepatocytes.Hepatic cytochrome P450s, phase II enzymes and nuclear receptors are downregulated in a Th2 environment during Schistosoma mansoni infection.Selective and cytokine-dependent regulation of hepatic transporters and bile acid homeostasis during infectious colitis in miceCancer, inflammation, and therapy: effects on cytochrome p450-mediated drug metabolism and implications for novel immunotherapeutic agents.Sexual differentiation of cytochrome P-450 in rat liver. Evidence for a constitutive isozyme as the male-specific 16 alpha-hydroxylase.Regulation of cytochromes P450 during inflammation and infection.Cytochromes P450 and flavin monooxygenases--targets and sources of nitric oxide.Preparation and characterization of monoclonal antibodies recognizing unique epitopes on sexually differentiated rat liver cytochrome P-450 isozymes.Rapid transcriptional suppression of rat cytochrome P450 genes by endotoxin treatment and its inhibition by curcumin.Inflammatory prompts produce isoform-specific changes in the expression of leukotriene B(4) omega-hydroxylases in rat liver and kidney.A role for one or more p450 enzymes in the response to sepsis.Effects of early maternal separation on ethanol intake, GABA receptors and metabolizing enzymes in adult rats.Purification, characterization, and pituitary regulation of the sex-specific cytochrome P-450 15 beta-hydroxylase from liver microsomes of untreated female rats.Suppression of rat hepatic microsomal cytochromes P450 by cyclophosphamide is correlated with plasma thyroid hormone levels and displays differential strain sensitivity.Physiological Regulation of Drug Metabolism and Transport: Pregnancy, Microbiome, Inflammation, Infection, and Fasting.Physiological and pathophysiological regulation of cytochrome P450.Endotoxemia in rats is associated with induction of the P4504A subfamily and suppression of several other forms of cytochrome P450.Effects of vanadate on hepatic cytochrome P-450 expression in streptozotocin-diabetic rats.Pretranslational suppression of cytochrome P-450h (IIC11) gene expression in rat liver after administration of interferon inducersGrowth hormone-dependent and -independent regulation of cytochrome P-450 isozyme expression in streptozotocin-diabetic ratsDifferences in glycogen, lipids, and enzymes in livers from rats flown on COSMOS 2044
P50
Q28567525-1331A6FD-91F2-47A2-AEF9-C42B1A558FBEQ28584243-2525E590-56D2-45F5-B692-ED0578523CBCQ31734154-8D3B2C33-C506-481A-A033-99732BD33DE3Q33538221-16918118-00BB-436B-85A7-EFC9665B549BQ33671358-EEC7BD2E-DBB0-4866-9B92-7903D84A7B05Q34042915-B9C0B9EE-BB42-48F8-826C-54B49BA29575Q34405854-CC03A705-0C22-402A-9909-5C7A1C866643Q34452293-0852BF3F-427E-42E6-87E6-EDF59C5839EBQ35035501-A1494BEA-1A94-4D08-882A-78864C296D83Q35114057-4D237195-864F-4FA3-B8D9-A91386E84FA9Q35708460-0F98CBA3-ED0B-4562-BCB0-69BD3E003B21Q35925387-4BD0B188-63E4-4D49-95D2-54FAED9D5B0CQ35995449-284D3F29-B1D8-4990-A76C-3FD8746C3D2DQ36320257-64BBADA0-9F61-4785-B0B1-7507A47A1505Q36343293-482D5F4D-D2D7-4F35-B7AA-7461EF65CF05Q36513088-987CD44F-CA5B-4E83-BAE9-A264177EF375Q36593723-212DDC62-7E5C-4354-BDC9-9F43E2EF9367Q37187997-909CDF11-7455-46FB-9860-843EC18F9B3CQ37188039-147D1D60-F972-4729-ABAB-075123E52ED8Q37405346-C4AE51F8-3131-4EEA-9769-26757F02C7A8Q37422679-2CCD44A8-69E7-42AD-9C1D-BCEE57AF0C08Q37663380-F74A9CBB-DDCC-43A5-965E-30AE7B4F9B63Q38225574-E9FADD4D-EBDE-460B-8E81-5BAC227493A8Q41496451-D1C9A996-FDC0-4A93-AAA7-8D611681660AQ41676809-4D1202DE-A0F0-4DE5-8370-2456E552FA71Q43767848-40E87E96-3845-481A-96A5-118D90AD3DD5Q44398066-97B9E75E-CD8A-475D-9447-D82487A85AAEQ44616426-E7E68FE5-4967-480C-958E-89915FF63355Q44673362-D107AAA2-068C-437F-8252-9D27AA72DC8CQ45220233-BCC6F0B9-49E3-4C75-AB00-377D0C2BFBF5Q46437606-86CE755E-1C77-4910-9D9D-6B6D6173EB7DQ48588990-6F0222E8-D8BA-436A-99A2-2762D52E05C3Q51043067-1B3D526F-40D3-4563-A229-0A2807E7D0EDQ51245820-E3573F1C-1E2D-466E-8774-7227F31E9356Q52181329-C429DE7E-4A3A-407F-A5A2-5194BDA45660Q54590928-B66A04E6-7998-4329-8001-6D1A0938C798Q64976546-7073C6FF-56BD-4965-8C7E-F5AA422D8DCCQ67684542-A64B0FC1-B7E0-4845-94E6-A317D3667726Q67684569-C4A3E603-FF18-4F2C-9F70-B500962690D4Q68047266-62700563-A313-43F3-B290-595848FD18D0
P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Edward T Morgan
@ast
Edward T Morgan
@en
Edward T Morgan
@es
Edward T Morgan
@nl
type
label
Edward T Morgan
@ast
Edward T Morgan
@en
Edward T Morgan
@es
Edward T Morgan
@nl
prefLabel
Edward T Morgan
@ast
Edward T Morgan
@en
Edward T Morgan
@es
Edward T Morgan
@nl
P106
P108
P1153
7201411674
P21
P31
P496
0000-0003-4273-2261