about
H19 acts as a trans regulator of the imprinted gene network controlling growth in miceC-terminal domains deliver the DNA replication factor Ciz1 to the nuclear matrixCiz1 promotes mammalian DNA replicationCiz1 cooperates with cyclin-A-CDK2 to activate mammalian DNA replication in vitroPiezo1 integration of vascular architecture with physiological force.A silencer element identified in Drosophila is required for imprinting of H19 reporter transgenes in mice.The nuclear matrix protein CIZ1 facilitates localization of Xist RNA to the inactive X-chromosome territory.Cure of ADPKD by selection for spontaneous genetic repair events in Pkd1-mutated iPS cellsVariant Ciz1 is a circulating biomarker for early-stage lung cancerTRPM2 channel deficiency prevents delayed cytosolic Zn2+ accumulation and CA1 pyramidal neuronal death after transient global ischemiaOCT4 activity during conversion of human intermediately reprogrammed stem cells to iPSCs through mesenchymal-epithelial transition.A differential role of macrophage TRPM2 channels in Ca²⁺ signaling and cell death in early responses to H₂O₂.Human and mouse induced pluripotent stem cells are differentially reprogrammed in response to kinase inhibitors.Cyclin E is recruited to the nuclear matrix during differentiation, but is not recruited in cancer cells.A state of reversible compensated ventricular dysfunction precedes pathological remodelling in response to cardiomyocyte-specific activity of angiotensin II type-1 receptor in mice.Cardiomyocyte--specific expression of the nuclear matrix protein, CIZ1, stimulates production of mono-nucleated cells with an extended window of proliferation in the postnatal mouse heart.Cancer-associated variant expression and interaction of CIZ1 with cyclin A1 in differentiating male germ cells.Distant cis-elements regulate imprinted expression of the mouse p57( Kip2) (Cdkn1c) gene: implications for the human disorder, Beckwith--Wiedemann syndrome.Appropriate expression of the mouse H19 gene utilises three or more distinct enhancer regions spread over more than 130 kb.Production of YAC transgenic mice by pronuclear injection.Imprinting and gene silencing in mice and Drosophila.Imprinting of Igf2 and H19 from a 130 kb YAC transgene.Comparative analysis of Igf-2/H19 imprinted domain: identification of a highly conserved intergenic DNase I hypersensitive region.Polycomb-group proteins are involved in silencing processes caused by a transgenic element from the murine imprinted H19/Igf2 region in Drosophila.Human menopausal and pregnant mare serum gonadotrophins in murine superovulation regimens for transgenic applications.Maintenance of epigenetic landscape requires CIZ1 and is corrupted in differentiated fibroblasts in long-term cultureMechanism of imprinting on mouse distal chromosome 7
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description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Justin F Ainscough
@ast
Justin F Ainscough
@en
Justin F Ainscough
@es
Justin F Ainscough
@nl
type
label
Justin F Ainscough
@ast
Justin F Ainscough
@en
Justin F Ainscough
@es
Justin F Ainscough
@nl
prefLabel
Justin F Ainscough
@ast
Justin F Ainscough
@en
Justin F Ainscough
@es
Justin F Ainscough
@nl
P106
P31
P496
0000-0003-0231-433X