Overview of the role of alcohol dehydrogenase and aldehyde dehydrogenase and their variants in the genesis of alcohol-related pathology
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The dappled nature of causes of psychiatric illness: replacing the organic-functional/hardware-software dichotomy with empirically based pluralismA systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom countsSide population cells as prototype of chemoresistant, tumor-initiating cellsAlcohol Intake and Breast Cancer Risk: Weighing the Overall EvidenceChronic ethanol exposure alters the lung proteome and leads to mitochondrial dysfunction in alveolar type 2 cellsA snapshot of the hepatic transcriptome: ad libitum alcohol intake suppresses expression of cholesterol synthesis genes in alcohol-preferring (P) ratsActivation of Human Salivary Aldehyde Dehydrogenase by Sulforaphane: Mechanism and SignificanceA possible role of acrolein in diabetic retinopathy: involvement of a VEGF/TGFβ signaling pathway of the retinal pigment epithelium in hyperglycemiaThe association of alcohol and alcohol metabolizing gene variants with diabetes and coronary heart disease risk factors in a white population.Modulation of Ethanol-Metabolizing Enzymes by Developmental Lead Exposure: Effects in Voluntary Ethanol ConsumptionSoft palatal melanosis, a simple predictor for neoplasia in the upper aerodigestive tract in Japanese alcoholic menA Mechanistic Review of Cell Death in Alcohol-Induced Liver Injury.Identification of liver proteins and their roles associated with carbon tetrachloride-induced hepatotoxicity.Aldehyde dehydrogenase 2 deficiency ameliorates alcoholic fatty liver but worsens liver inflammation and fibrosis in mice.Establishment of a Quick and Highly Accurate Breath Test for ALDH2 GenotypingSingle nucleotide polymorphisms of ADH1B, ADH1C and ALDH2 genes and esophageal cancer: a population-based case-control study in China.Autophagy in alcohol-induced multiorgan injury: mechanisms and potential therapeutic targetsThe pharmacogenetics of alcohol use disorderHaplotype-based study of the association of alcohol-metabolizing genes with alcohol dependence in four independent populations.Release and uptake of volatile organic compounds by human hepatocellular carcinoma cells (HepG2) in vitro.Analysis of volatile organic compounds liberated and metabolised by human umbilical vein endothelial cells (HUVEC) in vitro.Genome-wide identification of molecular pathways and biomarkers in response to arsenic exposure in zebrafish liver.Proteomic-based insight into Malpighian tubules of silkworm Bombyx mori.Nicotinic acetylcholine receptors are sensors for ethanol in lung fibroblasts.Effects of ALDH2 genotype, PPI treatment and L-cysteine on carcinogenic acetaldehyde in gastric juice and saliva after intragastric alcohol administration.Levels of explanation in psychiatric and substance use disorders: implications for the development of an etiologically based nosologyAlcohol metabolism in human cells causes DNA damage and activates the Fanconi anemia-breast cancer susceptibility (FA-BRCA) DNA damage response network.Retinoid regulation of antiviral innate immunity in hepatocytes.Protective role of ALDH2 against acetaldehyde-derived DNA damage in oesophageal squamous epithelium.Which alcohol use disorder criteria contribute to the association of ADH1B with alcohol dependence?Insights into the origin of postmortem ethanol.Metabolism and transport of oxazaphosphorines and the clinical implications.Effect of the allelic variants of aldehyde dehydrogenase ALDH2*2 and alcohol dehydrogenase ADH1B*2 on blood acetaldehyde concentrations.Strong protective effect of the aldehyde dehydrogenase gene (ALDH2) 504lys (*2) allele against alcoholism and alcohol-induced medical diseases in Asians.The role of cytochrome P450 enzymes in endogenous signalling pathways and environmental carcinogenesis.Inhibition of MAO-A and stimulation of behavioural activities in mice by the inactive prodrug form of the anti-influenza agent oseltamivirAlcohol dehydrogenase III exacerbates liver fibrosis by enhancing stellate cell activation and suppressing natural killer cells in mice.Differential blocking effects of the acetaldehyde-derived DNA lesion N2-ethyl-2'-deoxyguanosine on transcription by multisubunit and single subunit RNA polymerasesAssociation of ADH and ALDH genes with alcohol dependence in the Irish Affected Sib Pair Study of alcohol dependence (IASPSAD) sample.Are there genetic influences on addiction: evidence from family, adoption and twin studies.
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Overview of the role of alcohol dehydrogenase and aldehyde dehydrogenase and their variants in the genesis of alcohol-related pathology
description
wetenschappelijk artikel
@nl
наукова стаття, опублікована в лютому 2004
@uk
name
Overview of the role of alcoho ...... s of alcohol-related pathology
@en
Overview of the role of alcoho ...... s of alcohol-related pathology
@nl
type
label
Overview of the role of alcoho ...... s of alcohol-related pathology
@en
Overview of the role of alcoho ...... s of alcohol-related pathology
@nl
prefLabel
Overview of the role of alcoho ...... s of alcohol-related pathology
@en
Overview of the role of alcoho ...... s of alcohol-related pathology
@nl
P2093
P2860
P356
P1476
Overview of the role of alcoho ...... s of alcohol-related pathology
@en
P2093
David Chang
David W. Crabb
Michinaga Matsumoto
P2860
P356
10.1079/PNS2003327
P577
2004-02-01T00:00:00Z