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Human single-stranded DNA binding proteins are essential for maintaining genomic stabilityNéstor-Guillermo Progeria Syndrome: a biochemical insight into Barrier-to-Autointegration Factor 1, alanine 12 threonine mutationNovel insight into the composition of human single-stranded DNA-binding protein 1 (hSSB1)-containing protein complexeshSSB1 associates with and promotes stability of the BLM helicaseA data-driven structural model of hSSB1 (NABP2/OBFC2B) self-oligomerization.A structural analysis of DNA binding by hSSB1 (NABP2/OBFC2B) in solution.hSSB1 phosphorylation is dynamically regulated by DNA-PK and PPP-family protein phosphatases.hSSB1 (NABP2/OBFC2B) is regulated by oxidative stresshSSB1 (NABP2/ OBFC2B) is required for the repair of 8-oxo-guanine by the hOGG1-mediated base excision repair pathway.
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description
researcher
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wetenschapper
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հետազոտող
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name
Nicholas W Ashton
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Nicholas W Ashton
@en
Nicholas W Ashton
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Nicholas W Ashton
@nl
type
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Nicholas W Ashton
@ast
Nicholas W Ashton
@en
Nicholas W Ashton
@es
Nicholas W Ashton
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prefLabel
Nicholas W Ashton
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Nicholas W Ashton
@en
Nicholas W Ashton
@es
Nicholas W Ashton
@nl
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P21
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P496
0000-0002-9708-6319