Modulation of EZH2 expression in T cells improves efficacy of anti-CTLA-4 therapy

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Modulation of EZH2 expression in T cells improves efficacy of anti-CTLA-4 therapy

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im August 2018 veröffentlichter wissenschaftlicher Artikel

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wetenschappelijk artikel

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наукова стаття, опублікована в серпні 2018

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Modulation of EZH2 expression in T cells improves efficacy of anti-CTLA-4 therapy

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Modulation of EZH2 expression in T cells improves efficacy of anti-CTLA-4 therapy

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Modulation of EZH2 expression in T cells improves efficacy of anti-CTLA-4 therapy

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Modulation of EZH2 expression in T cells improves efficacy of anti-CTLA-4 therapy

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Modulation of EZH2 expression in T cells improves efficacy of anti-CTLA-4 therapy

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Modulation of EZH2 expression in T cells improves efficacy of anti-CTLA-4 therapy

@nl

P1476

Modulation of EZH2 expression in T cells improves efficacy of anti-CTLA-4 therapy

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P2093

Ana Aparicio

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Hao Zhao

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Irina Apostolou

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Jan Zhang

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Jill Skepner

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Liangwen Xiong

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Padmanee Sharma

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Patrick Trojer

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Sangeeta Goswami

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Sumit K Subudhi

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P2860

Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells

Role of histone H3 lysine 27 methylation in Polycomb-group silencing

The Polycomb complex PRC2 and its mark in life

Inflammation-induced repression of chromatin bound by the transcription factor Foxp3 in regulatory T cells

Transcriptional and epigenetic control of T helper cell specification: molecular mechanisms underlying commitment and plasticity.

CD19-/CD3-bispecific antibody of the BiTE class is far superior to tandem diabody with respect to redirected tumor cell lysis.

Stability and function of regulatory T cells is maintained by a neuropilin-1-semaphorin-4a axis.

The chromatin-modifying enzyme Ezh2 is critical for the maintenance of regulatory T cell identity after activation.

EZH2 is crucial for both differentiation of regulatory T cells and T effector cell expansion.

PRC2 Epigenetically Silences Th1-Type Chemokines to Suppress Effector T-Cell Trafficking in Colon Cancer

P304

3813-3818

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P31

scholarly article

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10.1172/JCI99760

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P407

English

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P478

128

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P50

James P. Allison

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2018-08-31T00:00:00Z

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29905573

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6118570

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