Unexpected role of B and T lymphocyte attenuator in sustaining cell survival during chronic allostimulation
about
Beyond CTLA-4 and PD-1, the Generation Z of Negative Checkpoint RegulatorsBTLA interaction with HVEM expressed on CD8(+) T cells promotes survival and memory generation in response to a bacterial infectionT cell intrinsic heterodimeric complexes between HVEM and BTLA determine receptivity to the surrounding microenvironment.T follicular helper expansion and humoral-mediated rejection are independent of the HVEM/BTLA pathwayB and T lymphocyte attenuator tempers early infection immunityTargeting of B and T lymphocyte associated (BTLA) prevents graft-versus-host disease without global immunosuppression.BTLA exhibits immune memory for αβ T cells in patients with active pulmonary tuberculosisDichotomous regulation of GVHD through bidirectional functions of the BTLA-HVEM pathway.CD8 T cell memory to a viral pathogen requires trans cosignaling between HVEM and BTLA.BTLA associates with increased Foxp3 expression in CD4(+) T cells in dextran sulfate sodium-induced colitisCharacterisation of cell functions and receptors in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME)The role of coinhibitory signaling pathways in transplantation and toleranceLow B and T lymphocyte attenuator expression on CD4+ T cells in the early stage of sepsis is associated with the severity and mortality of septic patients: a prospective cohort studyThe signaling networks of the herpesvirus entry mediator (TNFRSF14) in immune regulationBTLA marks a less-differentiated tumor-infiltrating lymphocyte subset in melanoma with enhanced survival properties.Immunoregulation by tumor necrosis factor superfamily member LIGHTImmunotherapies: the blockade of inhibitory signals.Convergent and divergent effects of costimulatory molecules in conventional and regulatory CD4+ T cellsA crucial role for HVEM and BTLA in preventing intestinal inflammationLymphotoxin network pathways shape the tumor microenvironmentThe TNF Receptor Superfamily in Co-stimulating and Co-inhibitory ResponsesThe TNF receptor and Ig superfamily members form an integrated signaling circuit controlling dendritic cell homeostasis.Targeting lymphocyte activation through the lymphotoxin and LIGHT pathwaysUnconventional ligand activation of herpesvirus entry mediator signals cell survival.Regulating the mucosal immune system: the contrasting roles of LIGHT, HVEM, and their various partnersSelective blockade of herpesvirus entry mediator-B and T lymphocyte attenuator pathway ameliorates acute graft-versus-host reaction.Experimental advances in understanding allergic airway inflammation.Interactions between herpesvirus entry mediator (TNFRSF14) and latency-associated transcript during herpes simplex virus 1 latency.Divide and conquer: Blocking graft versus host but not graft versus leukemia T cells with agonist BTLA co-inhibitory signals.Co-inhibitory molecules: Controlling the effectors or controlling the controllers?Enhanced Innate Inflammation Induced by Anti-BTLA Antibody in Dual Insult Model of Hemorrhagic Shock/Sepsis.B and T lymphocyte attenuator regulates T cell survival in the lung.Monoclonal antibodies to B and T lymphocyte attenuator (BTLA) have no effect on in vitro B cell proliferation and act to inhibit in vitro T cell proliferation when presented in a cis, but not trans, format relative to the activating stimulus.
P2860
Q26782799-3127794F-6ECC-4C96-AC9A-E04C1FEE19B2Q27303620-0633308F-2C41-4AFF-BE9D-0AD520F460EBQ33832366-D2FDAAC5-0E7E-41D9-87C7-08A5B98962CBQ33920121-BD378CBA-A18A-46C4-9790-A207AA83CFFFQ33954000-45A0D7D5-C512-4D61-A81B-EBC3A29D49D2Q34340643-057D5CDF-0DE0-4B66-BFA4-626B80509BD7Q34420572-47289C87-42A4-4AED-A763-A0D726A3AC90Q34707621-AF3C4FEB-6C5A-4D6E-A47F-4026AD29CED8Q35035884-7A44C5FF-9C26-4C9E-8E9F-E257C7207629Q35405897-8D0AD3AE-EE1C-4614-8C70-3F7570C1BE72Q35648873-03A1558E-E81F-4444-996D-E58D849DA6ABQ35928357-77F432F9-590D-4A59-8250-16244F2A4CCBQ36016266-6FDE8675-7986-4C75-957F-12C760CAD3CDQ36053977-EFEDE172-39FC-4210-8B16-EB63B1A22C11Q36060241-0005A61D-CAC7-4ECA-9FB1-D4B1625B7AFBQ36253506-0BE2582E-39FC-49DD-928A-EE5F37B3AD10Q36431677-D0543BD2-5B1F-48C7-B442-837CF4744A78Q36545602-B5A3AABB-C705-4B2D-9F26-5D75979EE568Q36699814-51CC2CBB-8A4B-4DE2-BA3B-C50C48ABF7C4Q36823937-60D7D800-45D7-4C5B-A961-2075094E04FCQ36940326-D8569EA0-7369-4E3A-9890-8087AC71D35CQ36969029-C8A57CEB-F0CB-47D6-BF90-005F2F1C844FQ37036159-8358205E-A970-40C8-B037-168A794C25FFQ37159087-23E344B6-C971-4ABC-8C62-244BE9FBABA7Q37398839-E815771F-0919-4BC3-9A49-A84844114762Q37585824-2A6F2489-75A0-439A-BD64-1938BD3649BAQ38070582-3BBA32BE-DC02-4EF9-85AD-E309EBC52DCAQ38310640-3D5978DA-A5D4-4304-992A-C09C2E5BEDDBQ39753388-437BDEA0-E1DA-4F6A-B507-6BDA0C9C1FA7Q39761212-24A5655C-B124-467F-AF1D-87AC3BA35BECQ40204862-C1AF577D-A5A4-40F0-A41B-C09005259B12Q42554635-085FEC1F-EF22-46F0-824D-9FBB7F7E5DCBQ44042290-DF9675C9-FBBC-410A-975D-B30C754BB095
P2860
Unexpected role of B and T lymphocyte attenuator in sustaining cell survival during chronic allostimulation
description
article
@en
im Mai 2007 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована в травні 2007
@uk
name
Unexpected role of B and T lym ...... during chronic allostimulation
@en
Unexpected role of B and T lym ...... during chronic allostimulation
@nl
type
label
Unexpected role of B and T lym ...... during chronic allostimulation
@en
Unexpected role of B and T lym ...... during chronic allostimulation
@nl
prefLabel
Unexpected role of B and T lym ...... during chronic allostimulation
@en
Unexpected role of B and T lym ...... during chronic allostimulation
@nl
P2093
P1476
Unexpected role of B and T lym ...... during chronic allostimulation
@en
P2093
John R Sedy
Kenneth M Murphy
Michelle A Hurchla
P304
P356
10.4049/JIMMUNOL.178.10.6073
P407
P577
2007-05-01T00:00:00Z