about
A novel mechanism for the biogenesis of outer membrane vesicles in Gram-negative bacteria.Adipose triglyceride lipase plays a key role in the supply of the working muscle with fatty acidsMonoglyceride lipase deficiency affects hepatic cholesterol metabolism and lipid-dependent gut transit in ApoE-/- mice.FAT SIGNALS--lipases and lipolysis in lipid metabolism and signaling.Fasting-induced G0/G1 switch gene 2 and FGF21 expression in the liver are under regulation of adipose tissue derived fatty acids.DAG tales: the multiple faces of diacylglycerol--stereochemistry, metabolism, and signalingA Class of Diacylglycerol Acyltransferase 1 Inhibitors Identified by a Combination of Phenotypic High-throughput Screening, Genomics, and GeneticsATGL and CGI-58 are lipid droplet proteins of the hepatic stellate cell line HSC-T6Adipose triglyceride lipase acts on neutrophil lipid droplets to regulate substrate availability for lipid mediator synthesis.Monoglyceride lipase deficiency modulates endocannabinoid signaling and improves plaque stability in ApoE-knockout mice.Deletion of Monoglyceride Lipase in Astrocytes Attenuates Lipopolysaccharide-induced NeuroinflammationLysosomal Acid Lipase Hydrolyzes Retinyl Ester and Affects Retinoid TurnoverNeutral lipid storage disease: genetic disorders caused by mutations in adipose triglyceride lipase/PNPLA2 or CGI-58/ABHD5.PNPLA1 Deficiency in Mice and Humans Leads to a Defect in the Synthesis of Omega-O-Acylceramides.Pharmacological inhibition of adipose triglyceride lipase corrects high-fat diet-induced insulin resistance and hepatosteatosis in mice.G0/G1 Switch Gene 2 Regulates Cardiac Lipolysis.Critical role of the peroxisomal protein PEX16 in white adipocyte development and lipid homeostasis.Measurement of lipolysisReduced incorporation of fatty acids into triacylglycerol in myotubes from obese individuals with type 2 diabetes.Growth retardation, impaired triacylglycerol catabolism, hepatic steatosis, and lethal skin barrier defect in mice lacking comparative gene identification-58 (CGI-58).α/β Hydrolase Domain-containing 6 (ABHD6) Degrades the Late Endosomal/Lysosomal Lipid Bis(monoacylglycero)phosphate.Secretory phospholipase A2 modified HDL rapidly and potently suppresses platelet activationA versatile ultra-high performance LC-MS method for lipid profilingStudies on the substrate and stereo/regioselectivity of adipose triglyceride lipase, hormone-sensitive lipase, and diacylglycerol-O-acyltransferases.Development of small-molecule inhibitors targeting adipose triglyceride lipase.Impact of Endothelial Lipase on Cholesterol Efflux Capacity of Serum and High-density Lipoprotein.Corrigendum: Pharmacological inhibition of adipose triglyceride lipase corrects high-fat diet-induced insulin resistance and hepatosteatosis in mice.Skin Barrier Development Depends on CGI-58 Protein Expression during Late-Stage Keratinocyte Differentiation.Epidermal overexpression of xenobiotic receptor PXR impairs the epidermal barrier and triggers Th2 immune response.Monoacylglycerol Lipases Act as Evolutionarily Conserved Regulators of Non-oxidative Ethanol MetabolismMonoglyceride lipase deficiency causes desensitization of intestinal cannabinoid receptor type 1 and increased colonic μ-opioid receptor sensitivity.The phospholipase PNPLA7 functions as a lysophosphatidylcholine hydrolase and interacts with lipid droplets through its catalytic domain.Disruption of Lipid Uptake in Astroglia Exacerbates Diet-Induced Obesity.Lipoprotein Lipase Maintains Microglial Innate Immunity in Obesity.Adipose triglyceride lipase affects triacylglycerol metabolism at brain barriers.Lipid droplets induced by secreted phospholipase A2 and unsaturated fatty acids protect breast cancer cells from nutrient and lipotoxic stress.Homocysteine regulates fatty acid and lipid metabolism in yeast.Loss of ABHD15 Impairs the Anti-lipolytic Action of Insulin by Altering PDE3B Stability and Contributes to Insulin Resistance.Lipidomic data on lipid droplet triglyceride remodelling associated with protection of breast cancer cells from lipotoxic stress.ABHD5 Stimulates PNPLA1-mediated Omega-O-Acylceramide Biosynthesis Essential for a Functional Skin Permeability Barrier
P50
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P50
description
researcher
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wetenschapper
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հետազոտող
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Thomas O Eichmann
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Thomas O Eichmann
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Thomas O Eichmann
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Thomas O Eichmann
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Thomas O Eichmann
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Thomas O Eichmann
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Thomas O Eichmann
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Thomas O Eichmann
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Thomas O Eichmann
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Thomas O Eichmann
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Thomas O Eichmann
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Thomas O Eichmann
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P106
P1153
55934314500
P21
P31
P496
0000-0002-8521-2795