about
A polymorphism at position 400 in the connection subdomain of HIV-1 reverse transcriptase affects sensitivity to NNRTIs and RNaseH activitySCT: a suite of programs for comparing atomistic models with small-angle scattering data.Atomistic modelling of scattering data in the Collaborative Computational Project for Small Angle Scattering (CCP-SAS).Global Conformational Dynamics of HIV-1 Reverse Transcriptase Bound to Non-Nucleoside Inhibitors.The solution structures of native and patient monomeric human IgA1 reveal asymmetric extended structures: implications for function and IgAN diseaseLoop interactions and dynamics tune the enzymatic activity of the human histone deacetylase 8.Computing Clinically Relevant Binding Free Energies of HIV-1 Protease Inhibitors.From base pair to bedside: molecular simulation and the translation of genomics to personalized medicine.An Ensemble-Based Protocol for the Computational Prediction of Helix-Helix Interactions in G Protein-Coupled Receptors using Coarse-Grained Molecular DynamicsRapid, Accurate, Precise, and Reliable Relative Free Energy Prediction Using Ensemble Based Thermodynamic Integration.Domain structure of human complement C4b extends with increasing NaCl concentration: implications for its regulatory mechanism.Thumbs down for HIV: domain level rearrangements do occur in the NNRTI-bound HIV-1 reverse transcriptase.Accurate ensemble molecular dynamics binding free energy ranking of multidrug-resistant HIV-1 proteases.Quantized water access to the HIV-1 protease active site as a proposed mechanism for cooperative mutations in drug affinity.Automated molecular simulation based binding affinity calculator for ligand-bound HIV-1 proteases.Structure, dynamics, and function of the hammerhead ribozyme in bulk water and at a clay mineral surface from replica exchange molecular dynamics.Mechanism of drug efficacy within the EGF receptor revealed by microsecond molecular dynamics simulation.Application of ESMACS binding free energy protocols to diverse datasets: Bromodomain-containing protein 4Resolution of discordant HIV-1 protease resistance rankings using molecular dynamics simulations
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description
researcher
@en
wetenschapper
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հետազոտող
@hy
name
David W Wright
@ast
David W Wright
@en
David W Wright
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David W Wright
@nl
type
label
David W Wright
@ast
David W Wright
@en
David W Wright
@es
David W Wright
@nl
prefLabel
David W Wright
@ast
David W Wright
@en
David W Wright
@es
David W Wright
@nl
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P106
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0000-0002-5124-8044