Structure- and property-based design of factor Xa inhibitors: Pyrrolidin-2-ones with acyclic alanyl amides as P4 motifs
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Rapid and accurate prediction and scoring of water molecules in protein binding sitesCSAR 2014: A Benchmark Exercise Using Unpublished Data from Pharma.Beyond Membrane Protein Structure: Drug Discovery, Dynamics and Difficulties.Thermodynamics of Water in an Enzyme Active Site: Grid-Based Hydration Analysis of Coagulation Factor Xa.Protein pharmacophore selection using hydration-site analysis.Role of the active-site solvent in the thermodynamics of factor Xa ligand binding.Inclusion of multiple fragment types in the site identification by ligand competitive saturation (SILCS) approachCSAR benchmark exercise of 2010: combined evaluation across all submitted scoring functions.Developments in factor Xa inhibitors for the treatment of thromboembolic disorders.A medicinal chemist's guide to molecular interactionsOral, direct thrombin and factor Xa inhibitors: the replacement for warfarin, leeches, and pig intestines?WATsite: hydration site prediction program with PyMOL interface.Conformational behaviour of peptides containing a 2-pyrrolidinemethanesulfonic acid (2PyMS) residue.
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P2860
Structure- and property-based design of factor Xa inhibitors: Pyrrolidin-2-ones with acyclic alanyl amides as P4 motifs
description
article
@en
im Dezember 2006 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована в грудні 2006
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name
Structure- and property-based ...... lic alanyl amides as P4 motifs
@en
Structure- and property-based ...... lic alanyl amides as P4 motifs
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type
label
Structure- and property-based ...... lic alanyl amides as P4 motifs
@en
Structure- and property-based ...... lic alanyl amides as P4 motifs
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prefLabel
Structure- and property-based ...... lic alanyl amides as P4 motifs
@en
Structure- and property-based ...... lic alanyl amides as P4 motifs
@nl
P2093
P1476
Structure- and property-based ...... lic alanyl amides as P4 motifs
@en
P2093
Alan D. Borthwick
Andrew M. Mason
Anthony J. Pateman
Champa Patel
Chuen Chan
Cynthia L. Burns-Kurtis
David Brown
Gita P. Shah
Hawa Diallo
Helen E. Weston
P304
P356
10.1016/J.BMCL.2006.09.001
P407
P577
2006-12-01T00:00:00Z