about
A virtual lymph node model to dissect the requirements for T-cell activation by synapses and kinapses.A role for the immediate early gene product c-fos in imprinting T cells with short-term memory for signal summationCompetition for antigen determines the stability of T cell-dendritic cell interactions during clonal expansion.Subcellular dynamics of T cell immunological synapses and kinapses in lymph nodes.The mechanism of anti-CD20-mediated B cell depletion revealed by intravital imagingCollective nitric oxide production provides tissue-wide immunity during Leishmania infection.Dynamics of thymocyte-stromal cell interactions visualized by two-photon microscopy.Semaphorin 3F and neuropilin-2 control the migration of human T-cell precursorsVisualizing thymocyte motility using 2-photon microscopy.Dynamic behavior of T cells and thymocytes in lymphoid organs as revealed by two-photon microscopy.Signal strength regulates antigen-mediated T-cell deceleration by distinct mechanisms to promote local exploration or arrestCellular orchestration of T cell priming in lymph nodes.Mycolactone activation of Wiskott-Aldrich syndrome proteins underpins Buruli ulcer formation.Decoding the dynamics of T cell-dendritic cell interactions in vivo.Diversity, functionality, and stability of the T cell repertoire derived in vivo from a single human T cell precursor.Signal 0 for guided priming of CTLs: NKT cells do it too.Functional immunoimaging: the revolution continues.Visualizing how T cells collect activation signals in vivo.Induction, Propagation, and Activity of Host Nitric Oxide: Lessons from Leishmania Infection.In vivo imaging of inflammasome activation reveals a subcapsular macrophage burst response that mobilizes innate and adaptive immunity.Photoconvertible pathogen labeling reveals nitric oxide control of Leishmania major infection in vivo via dampening of parasite metabolism.Quantifying subcellular distribution of fluorescent fusion proteins in cells migrating within tissues.Preexisting BCG-specific T cells improve intravesical immunotherapy for bladder cancer.Intravital two-photon imaging of natural killer cells and dendritic cells in lymph nodes.Subcapsular sinus macrophages promote NK cell accumulation and activation in response to lymph-borne viral particles.Restricted microbiota and absence of cognate TCR antigen leads to an unbalanced generation of Th17 cells.Manipulating leukocyte interactions in vivo through optogenetic chemokine release.Dissecting T cell contraction in vivo using a genetically encoded reporter of apoptosis.Regulatory T cells increase the avidity of primary CD8+ T cell responses and promote memory.Termination of T cell priming relies on a phase of unresponsiveness promoting disengagement from APCs and T cell division.How many dendritic cells are required to initiate a T-cell response?CD11c-expressing Ly6C+CCR2+ monocytes constitute a reservoir for efficient Leishmania proliferation and cell-to-cell transmissionCutting Edge: A dual role for type I IFNs during polyinosinic-polycytidylic acid-induced NK cell activation.CD4+ T Cells Rely on a Cytokine Gradient to Control Intracellular Pathogens beyond Sites of Antigen PresentationImpact of negative selection on the T cell repertoire reactive to a self-peptide: a large fraction of T cell clones escapes clonal deletionThe peripheral CD8 T cell repertoire is largely independent of the presence of intestinal floraEnrichment of antigen-specific T lymphocytes by panning on immobilized MHC-peptide complexesIndividual variations in the murine T cell response to a specific peptide reflect variability in naive repertoiresThe Qa-1b molecule binds to a large subpopulation of murine NK cellsReal-time manipulation of T cell-dendritic cell interactions in vivo reveals the importance of prolonged contacts for CD4+ T cell activation
P50
Q27323013-89101316-CF84-48C9-83CA-932C4245D2D7Q28477933-42EE796D-2F69-4FA5-A62E-3B516229FAE7Q30479188-BB4F363D-0D03-4863-BA8E-271263071BA7Q30493744-152CE3B9-6DAF-45BA-BD48-D28F93791761Q30559277-97A9AE6B-F79D-4419-B11E-A993AC9831CEQ30575293-C4A1BFAF-F570-444D-B3AC-2906F71A5EDBQ32127240-805D211B-AA56-4F31-9CC0-B410B41CCE7BQ35214194-11E4A834-DBEE-4E58-8C2B-61EEACF42335Q35216940-7E156DB2-981D-44AC-B128-BE5EA8DD857CQ35882927-C37AFCEB-4045-4789-B11D-36A3F373051FQ36120402-196F5AC6-4950-458E-8D78-BA6D5A79AAA7Q36502312-ADAAB12C-1C2B-4A8C-BB23-E42802E2B8C1Q36733497-B1C43CA3-FD6B-4054-B122-31F86D9F3900Q37084896-7D262637-2261-499B-9B8A-68C98D94E8D6Q37149903-77BAC8AF-3F31-4E76-A04C-F5A8636C03CEQ37714323-FFDC5BB8-F652-4DBC-B0DB-461ACDC98441Q38061859-30F513D8-81FB-4F63-B841-7D8F3B5F6F79Q38189926-5CD9438A-7567-41FD-B8B2-59F59758063EQ38600399-31771310-5E7F-4179-9345-A81888C13B99Q40861827-DDCE9239-9244-4348-8899-92BB05675A68Q42243715-768CDCBC-C2CC-4A9F-9D96-35F5C174664DQ44954762-9964AFB7-B8B3-4925-B2FA-D88913519ABEQ47655009-63A050F3-BB84-4FBF-AD6C-31BE15EFF7A2Q48505474-5AE3EE33-E168-4E86-9C23-C69DDB58D1CDQ50489226-4CE76AF3-3F0A-444F-93B5-E045D5DC47BEQ50530610-31695679-3F1F-428A-B78B-167840275D37Q50863268-8AF5F8C3-5F4B-42D2-97B8-4F9C8FD86623Q50928260-D08A882F-4D7E-4B28-B4EA-5595523C519DQ50930669-2A4DB016-A42F-4CF2-ADA0-F5C482330791Q52723732-3791CB1D-E127-4EB5-AD90-943761EA7305Q56838955-E1D8F725-07D7-477B-8368-94BD19775B72Q57805454-28457A7E-D7D1-4882-BA25-5E799295C5E0Q58478648-54D9D123-3E67-4D8D-883D-349EF8B1A8AEQ59387555-69E8B585-4B2C-405D-9BF4-645C636C3E96Q73406538-D7FD13A6-4E8D-4D85-8363-4370478C03BFQ73615651-C11829F3-3EAD-41EB-9F23-DF0ABC50881FQ73886861-9627B9FD-BFF0-49FA-9C44-6FFEAF6FB708Q77206852-963F195D-F135-4A08-849F-B94C54896586Q77715048-191BA868-E745-4C7F-B608-D6B879B3BF26Q81469542-77FB7A74-578E-44EB-BF43-2FEA425B4EC8
P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Philippe Bousso
@ast
Philippe Bousso
@en
Philippe Bousso
@es
Philippe Bousso
@nl
type
label
Philippe Bousso
@ast
Philippe Bousso
@en
Philippe Bousso
@es
Philippe Bousso
@nl
prefLabel
Philippe Bousso
@ast
Philippe Bousso
@en
Philippe Bousso
@es
Philippe Bousso
@nl
P106
P31
P496
0000-0002-6362-561X