Tungstate activates BK channels in a β subunit- and Mg2+-dependent manner: relevance for arterial vasodilatation
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An update to the toxicological profile for water-soluble and sparingly soluble tungsten substancesTungstate-targeting of BKαβ1 channels tunes ERK phosphorylation and cell proliferation in human vascular smooth muscle.Preclinical and Clinical Studies for Sodium Tungstate: Application in Humans.BK channels in rat and human pulmonary smooth muscle cells are BKα-β1 functional complexes lacking the oxygen-sensitive stress axis regulated exon insert.Pharmacological consequences of the coexpression of BK channel α and auxiliary β subunitsA Combination of Intravenous Genistein Plus Mg2+ Enhances Antihypertensive Effects in SHR by Endothelial Protection and BKCa Channel Inhibition.Mg²⁺-dependent modulation of BKCa channels by genistein in rat arteriolar smooth muscle cells.BK channel activation by tungstate requires the β1 subunit extracellular loop residues essential to modulate voltage sensor function and channel gating.
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P2860
Tungstate activates BK channels in a β subunit- and Mg2+-dependent manner: relevance for arterial vasodilatation
description
im April 2012 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована у квітні 2012
@uk
name
Tungstate activates BK channel ...... ce for arterial vasodilatation
@en
Tungstate activates BK channel ...... ce for arterial vasodilatation
@nl
type
label
Tungstate activates BK channel ...... ce for arterial vasodilatation
@en
Tungstate activates BK channel ...... ce for arterial vasodilatation
@nl
prefLabel
Tungstate activates BK channel ...... ce for arterial vasodilatation
@en
Tungstate activates BK channel ...... ce for arterial vasodilatation
@nl
P2093
P2860
P50
P356
P1476
Tungstate activates BK channel ...... ce for arterial vasodilatation
@en
P2093
Ana I. Fernández-Mariño
Antonio Castellano
Cristina Porras-González
Juan Ureña
Patricia González-Rodríguez
P2860
P356
10.1093/CVR/CVS139
P577
2012-04-02T00:00:00Z