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Effect of ligand binding on human D-amino acid oxidase: implications for the development of new drugs for schizophrenia treatmentThe x-ray structure of D-amino acid oxidase at very high resolution identifies the chemical mechanism of flavin-dependent substrate dehydrogenationAminoacetone oxidase from Streptococcus oligofermentans belongs to a new three-domain family of bacterial flavoproteinsPhysiological functions of D-amino acid oxidases: from yeast to humansContribution of the dimeric state to the thermal stability of the flavoprotein D-amino acid oxidase.Modulating D-amino acid oxidase substrate specificity: production of an enzyme for analytical determination of all D-amino acids by directed evolution.Evolution of an acylase active on cephalosporin CProduction of recombinant cholesterol oxidase containing covalently bound FAD in Escherichia coli.Decreased free d-aspartate levels are linked to enhanced d-aspartate oxidase activity in the dorsolateral prefrontal cortex of schizophrenia patientsMetabolism of the neuromodulator D-serine.D-amino acid oxidase inhibitors as a novel class of drugs for schizophrenia therapy.O2 reactivity of flavoproteins: dynamic access of dioxygen to the active site and role of a H+ relay system in D-amino acid oxidaseOptimizing Escherichia coli as a protein expression platform to produce Mycobacterium tuberculosis immunogenic proteinsD-amino acid oxidase-nanoparticle system: a potential novel approach for cancer enzymatic therapy.One single method to produce native and Tat-fused recombinant human α-synuclein in Escherichia coli.P53 family members modulate the expression of PRODH, but not PRODH2, via intronic p53 response elements.Identity of the NMDA receptor coagonist is synapse specific and developmentally regulated in the hippocampus.Circuit-specific changes in D-serine-dependent activation of the N-methyl-D-aspartate receptor in the aging hippocampus.D-Serine and Glycine Differentially Control Neurotransmission during Visual Cortex Critical Period.Production and characterization of a novel antifungal chitinase identified by functional screening of a suppressive-soil metagenomeUnderstanding renal nuclear protein accumulation: an in vitro approach to explain an in vivo phenomenon.Olanzapine, but not clozapine, increases glutamate release in the prefrontal cortex of freely moving mice by inhibiting D-aspartate oxidase activity.New biotech applications from evolved D-amino acid oxidases.Structure-function relationships in human D-amino acid oxidase.Cephalosporin C acylase: dream and(/or) reality.L-amino acid oxidase as biocatalyst: a dream too far?Role of arginine 285 in the active site of Rhodotorula gracilis D-amino acid oxidase. A site-directed mutagenesis study.Lignin-degrading enzymes.Conversion of the dimeric D-amino acid oxidase from Rhodotorula gracilis to a monomeric form. A rational mutagenesis approach.Breaking the mirror: l-Amino acid deaminase, a novel stereoselective biocatalyst.Glycosylation of Recombinant Antigenic Proteins from Mycobacterium tuberculosis: In Silico Prediction of Protein Epitopes and Ex Vivo Biological Evaluation of New Semi-Synthetic Glycoconjugates.Elucidating the role of the pLG72 R30K substitution in schizophrenia susceptibility.G72 primate-specific gene: a still enigmatic element in psychiatric disorders.Recombinant human Tat-Hsp70-2: A tool for neuroprotection.The Gliotransmitter d-Serine Promotes Synapse Maturation and Axonal Stabilization In Vivo.Application of a rapid HILIC-UV method for synthesis optimization and stability studies of immunogenic neo-glycoconjugates.Insight into conformational modification of alpha-synuclein in the presence of neuronal whole cells and of their isolated membranes.Structure-function relationships in human d-amino acid oxidase variants corresponding to known SNPs.New synthesis and biodistribution of the D-amino acid oxidase-magnetic nanoparticle system.The degradation (by distinct pathways) of human D-amino acid oxidase and its interacting partner pLG72--two key proteins in D-serine catabolism in the brain.
P50
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P50
description
researcher ORCID: 0000-0003-1733-7243
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name
Loredano Pollegioni
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Loredano Pollegioni
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Loredano Pollegioni
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Loredano Pollegioni
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Loredano Pollegioni
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Loredano Pollegioni
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Loredano Pollegioni
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Loredano Pollegioni
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Loredano Pollegioni
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Loredano Pollegioni
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Loredano Pollegioni
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Loredano Pollegioni
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P106
P1153
7003324271
P31
P496
0000-0003-1733-7243