Identification of Serum-Derived Sphingosine-1-Phosphate as a Small Molecule Regulator of YAP
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Mutant Gq/11 promote uveal melanoma tumorigenesis by activating YAPSphingosine-1-Phosphate Receptor-2 Antagonists: Therapeutic Potential and Potential RisksRegulation of TAZ in cancerG Protein-Coupled Receptors in CancerMechanisms of Hippo pathway regulationA Review: Molecular Aberrations within Hippo Signaling in Bone and Soft-Tissue SarcomasThe two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatmentThe sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticityTargeting the Hippo Signaling Pathway for Tissue Regeneration and Cancer TherapyYAP and TAZ: a nexus for Hippo signaling and beyondEmerging evidence on the role of the Hippo/YAP pathway in liver physiology and cancerHippo Pathway in Organ Size Control, Tissue Homeostasis, and CancerHistone acetylation-mediated regulation of the Hippo pathwayActin cytoskeleton regulates Hippo signalingAdhesion to fibronectin regulates Hippo signaling via the FAK-Src-PI3K pathway.The Hippo signaling pathway in stem cell biology and cancerWhat do mechanotransduction, Hippo, Wnt, and TGFβ have in common? YAP and TAZ as key orchestrating molecules in ocular health and disease.Angiomotins link F-actin architecture to Hippo pathway signaling.Framework to function: mechanosensitive regulators of gene transcriptionThe Hippo pathway in disease and therapy: cancer and beyondPhosphorylation of angiomotin by Lats1/2 kinases inhibits F-actin binding, cell migration, and angiogenesisEnergy stress regulates hippo-YAP signaling involving AMPK-mediated regulation of angiomotin-like 1 protein.The hippo pathway in heart development, regeneration, and diseasesThe tyrosine phosphatase PTPN14 is a negative regulator of YAP activity.Prenatal exposure to dietary fat induces changes in the transcriptional factors, TEF and YAP, which may stimulate differentiation of peptide neurons in rat hypothalamusIntraovarian control of early folliculogenesisPhenotypic regulation of the sphingosine 1-phosphate receptor miles apart by G protein-coupled receptor kinase 2.Cellular energy stress induces AMPK-mediated regulation of YAP and the Hippo pathwayHippo signaling pathway in liver and pancreas: the potential drug target for tumor therapy.Inhibition of RHO-ROCK signaling enhances ICM and suppresses TE characteristics through activation of Hippo signaling in the mouse blastocyst.Actin polymerization-enhancing drugs promote ovarian follicle growth mediated by the Hippo signaling effector YAP.Estrogen regulates Hippo signaling via GPER in breast cancerPhosphorylation of the Hippo Pathway Component AMOTL2 by the mTORC2 Kinase Promotes YAP Signaling, Resulting in Enhanced Glioblastoma Growth and Invasiveness.A miR-130a-YAP positive feedback loop promotes organ size and tumorigenesis.RAC-LATS1/2 signaling regulates YAP activity by switching between the YAP-binding partners TEAD4 and RUNX3.Pancreas lineage allocation and specification are regulated by sphingosine-1-phosphate signallingYap is required for ependymal integrity and is suppressed in LPA-induced hydrocephalusRole of substratum stiffness in modulating genes associated with extracellular matrix and mechanotransducers YAP and TAZThe role of LPA and YAP signaling in long-term migration of human ovarian cancer cells.Protein kinase A activates the Hippo pathway to modulate cell proliferation and differentiation.
P2860
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P2860
Identification of Serum-Derived Sphingosine-1-Phosphate as a Small Molecule Regulator of YAP
description
wetenschappelijk artikel
@nl
наукова стаття, опублікована в серпні 2012
@uk
name
Identification of Serum-Derive ...... mall Molecule Regulator of YAP
@en
Identification of Serum-Derive ...... mall Molecule Regulator of YAP
@nl
type
label
Identification of Serum-Derive ...... mall Molecule Regulator of YAP
@en
Identification of Serum-Derive ...... mall Molecule Regulator of YAP
@nl
prefLabel
Identification of Serum-Derive ...... mall Molecule Regulator of YAP
@en
Identification of Serum-Derive ...... mall Molecule Regulator of YAP
@nl
P2093
P1476
Identification of Serum-Derive ...... mall Molecule Regulator of YAP
@en
P2093
Chunlei Wu
Eric C. Peters
Eric Miller
Jiayi Yang
Michael DeRan
P304
P356
10.1016/J.CHEMBIOL.2012.07.005
P577
2012-08-01T00:00:00Z