about
Direct reversal of glucocorticoid resistance by AKT inhibition in acute lymphoblastic leukemiaThe relevance of PTEN-AKT in relation to NOTCH1-directed treatment strategies in T-cell acute lymphoblastic leukemiaJAK3 mutants transform hematopoietic cells through JAK1 activation, causing T-cell acute lymphoblastic leukemia in a mouse modelIncreased expression of the breast cancer resistance protein (BCRP) in relapsed or refractory acute myeloid leukemia (AML)IL-7 Receptor Mutations and Steroid Resistance in Pediatric T cell Acute Lymphoblastic Leukemia: A Genome Sequencing StudyPHF6 mutations in T-cell acute lymphoblastic leukemiaImmature MEF2C-dysregulated T-cell leukemia patients have an early T-cell precursor acute lymphoblastic leukemia gene signature and typically have non-rearranged T-cell receptors.Angiopoietin-like protein 3 promotes preservation of stemness during ex vivo expansion of murine hematopoietic stem cellsOncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia.The TLX1 oncogene drives aneuploidy in T cell transformationZEB2 drives immature T-cell lymphoblastic leukaemia development via enhanced tumour-initiating potential and IL-7 receptor signalling.Reverse engineering of TLX oncogenic transcriptional networks identifies RUNX1 as tumor suppressor in T-ALL.Trib2 Suppresses Tumor Initiation in Notch-Driven T-ALL.Lentiviral gene transfer into human and murine hematopoietic stem cells: size mattersFBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitorsWT1 mutations in T-ALLGenetic rearrangements in relation to immunophenotype and outcome in T-cell acute lymphoblastic leukaemia.NKL homeobox genes in leukemia.t(14;18), a journey to eternity.ABT-199 mediated inhibition of BCL-2 as a novel therapeutic strategy in T-cell acute lymphoblastic leukemia.CHK1 overexpression in T-cell acute lymphoblastic leukemia is essential for proliferation and survival by preventing excessive replication stress.Inactivation of KLF4 promotes T-cell acute lymphoblastic leukemia and activates the MAP2K7 pathway.PTPN2 negatively regulates oncogenic JAK1 in T-cell acute lymphoblastic leukemia.A novel method to compensate for different amplification efficiencies between patient DNA samples in quantitative real-time PCR.Bcl-2 protects against apoptosis induced by antimycin A and bongkrekic acid without restoring cellular ATP levels.Discovery and functional characterization of a germline, CSF2RB-activating mutation in leukemia.MEK and PI3K-AKT inhibitors synergistically block activated IL7 receptor signaling in T-cell acute lymphoblastic leukemia.Structural modeling of JAK1 mutations in T-cell acute lymphoblastic leukemia reveals a second contact site between pseudokinase and kinase domains.mRNA expression levels of (co)chaperone molecules of the glucocorticoid receptor are not involved in glucocorticoid resistance in pediatric ALL.Late recurrence of childhood T-cell acute lymphoblastic leukemia frequently represents a second leukemia rather than a relapse: first evidence for genetic predisposition.MAFB enhances oncogenic Notch signaling in T cell acute lymphoblastic leukemia.New type of t(14;18) in a non-Hodgkin's lymphoma provides insight in molecular events in early B-cell differentiation.Overexpression of LMO2 causes aberrant human T-Cell development in vivo by three potentially distinct cellular mechanisms.Backtracking of ALL to cord blood.Cooperative genetic defects in TLX3 rearranged pediatric T-ALL.A new recurrent 9q34 duplication in pediatric T-cell acute lymphoblastic leukemia.Dynamics of circulating t(14;18)-positive cells during first-line and subsequent lines of treatment in follicular lymphoma.Outcome in children with Down's syndrome and acute lymphoblastic leukemia: role of IKZF1 deletions and CRLF2 aberrationsPTEN microdeletions in T-cell acute lymphoblastic leukemia are caused by illegitimate RAG-mediated recombination eventsQuantitation of follicular non-Hodgkin's lymphoma cells carrying t(14;18) by competitive polymerase chain reaction
P50
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P50
description
onderzoeker
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researcher
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հետազոտող
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name
Jules P Meijerink
@ast
Jules P Meijerink
@en
Jules P Meijerink
@es
Jules P Meijerink
@nl
type
label
Jules P Meijerink
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Jules P Meijerink
@en
Jules P Meijerink
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Jules P Meijerink
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prefLabel
Jules P Meijerink
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Jules P Meijerink
@en
Jules P Meijerink
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Jules P Meijerink
@nl
P106
P31
P496
0000-0002-6860-798X