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Substrate specificity, membrane topology, and activity regulation of human alkaline ceramidase 2 (ACER2)Golgi alkaline ceramidase regulates cell proliferation and survival by controlling levels of sphingosine and S1PCeramide generated by sphingomyelin hydrolysis and the salvage pathway is involved in hypoxia/reoxygenation-induced Bax redistribution to mitochondria in NT-2 cellsPreoperative Neutrophil-to-Lymphocyte Ratio as a New Prognostic Marker in Hepatocellular Carcinoma after Curative Resection.Golgi fragmentation is associated with ceramide-induced cellular effects.Role of alkaline ceramidases in the generation of sphingosine and its phosphate in erythrocytes.Mitochondrially targeted ceramides preferentially promote autophagy, retard cell growth, and induce apoptosis.High KIF18A expression correlates with unfavorable prognosis in primary hepatocellular carcinomap38 mitogen-activated protein kinase/activator protein-1 involved in serum deprivation-induced human alkaline ceramidase 2 upregulationCaspase-mediated cleavage of RNA-binding protein HuR regulates c-Myc protein expression after hypoxic stress.GPR40/FFA1 and neutral sphingomyelinase are involved in palmitate-boosted inflammatory response of microvascular endothelial cells to LPS.TLR4 activation and IL-6-mediated cross talk between adipocytes and mononuclear cells synergistically stimulate MMP-1 expression.High USP22 expression indicates poor prognosis in hepatocellular carcinoma.Periodontal CD14 mRNA expression is downregulated in patients with chronic periodontitis and type 2 diabetes.MicroRNA-17-92 controls T-cell responses in graft-versus-host disease and leukemia relapse in mice.A comprehensive method for predicting fatal liver failure of patients with liver cancer resection.Elevated preoperative aspartate aminotransferase to lymphocyte ratio index as an independent prognostic factor for patients with hepatocellular carcinoma after hepatic resection.Upregulation of hyaluronan-mediated motility receptor in hepatocellular carcinoma predicts poor survival.Role of aldo-keto reductases in development of prostate and breast cancer.A novel prognostic biomarker SPC24 up-regulated in hepatocellular carcinoma.Aldo-keto Reductase Family 1 Member B 10 Mediates Liver Cancer Cell Proliferation through Sphingosine-1-Phosphate.T-bet Promotes Acute Graft-versus-Host Disease by Regulating Recipient Hematopoietic Cells in Mice.CD8(+) Tregs promote GVHD prevention and overcome the impaired GVL effect mediated by CD4(+) Tregs in micePreoperative Aspartate Aminotransferase to White Blood Cell Count Ratio Predicting Postoperative Outcomes of Hepatocellular Carcinoma.Neutral ceramidase-enriched exosomes prevent palmitic acid-induced insulin resistance in H4IIEC3 hepatocytes.AMPK inhibitor Compound C stimulates ceramide production and promotes Bax redistribution and apoptosis in MCF7 breast carcinoma cells.AKR1B10 promotes breast cancer metastasis through integrin α5/δ-catenin mediated FAK/Src/Rac1 signaling pathway.Simvastatin inhibits lipopolysaccharide-induced osteoclastogenesis and reduces alveolar bone loss in experimental periodontal diseaseAssociation between miR-199a rs74723057 and MET rs1621 polymorphisms and the risk of hepatocellular carcinoma.Low-dose cytokine-induced neutral ceramidase secretion from INS-1 cells via exosomes and its anti-apoptotic effect.TLR4 antagonist reduces early-stage atherosclerosis in diabetic apolipoprotein E-deficient mice.Coactivation of TLR4 and TLR2/6 coordinates an additive augmentation on IL-6 gene transcription via p38MAPK pathway in U937 mononuclear cells.Acute activation of acid ceramidase affects cytokine-induced cytotoxicity in rat islet beta-cells.Toll-like receptor 4 activation in microvascular endothelial cells triggers a robust inflammatory response and cross talk with mononuclear cells via interleukin-6.Targeted interfering DEP domain containing 1 protein induces apoptosis in A549 lung adenocarcinoma cells through the NF-κB signaling pathwayInhibition of AMP-activated protein kinase pathway sensitizes human leukemia K562 cells to nontoxic concentration of doxorubicin.MD-2 is involved in the stimulation of matrix metalloproteinase-1 expression by interferon-γ and high glucose in mononuclear cells - a potential role of MD-2 in Toll-like receptor 4-independent signalling.Rhodium (II) complex with 2-benzoylpyridine, a novel potential chemotherapeutic drug, induces cell cycle arrest and apoptosis in HepG2 cells.Natural IgM initiates an inflammatory response important for both hepatic ischemia reperfusion injury and regeneration.The role of acid sphingomyelinase and caspase 5 in hypoxia-induced HuR cleavage and subsequent apoptosis in hepatocytes.
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P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Junfei Jin
@ast
Junfei Jin
@en
Junfei Jin
@es
Junfei Jin
@nl
type
label
Junfei Jin
@ast
Junfei Jin
@en
Junfei Jin
@es
Junfei Jin
@nl
prefLabel
Junfei Jin
@ast
Junfei Jin
@en
Junfei Jin
@es
Junfei Jin
@nl
P106
P31
P496
0000-0002-9237-9024